Reviewed, UniProtKB/Swiss-Prot Q3MB82 (CAPP_ANAVT)

Names and origin

Protein names

Recommended name:
    Phosphoenolpyruvate carboxylase
      Short name=PEPCase
      Short name=PEPC
    EC=4.1.1.31

Gene names

Name:	ppc
Ordered Locus Names:	Ava_2134

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	1023 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. HAMAP MF_00595
Catalytic activity	Phosphate + oxaloacetate = H2O + phosphoenolpyruvate + CO2. HAMAP MF_00595
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle. HAMAP MF_00595
Sequence similarities	Belongs to the PEPCase type 1 family.

Ontologies

Keywords
Biological process	Carbon dioxide fixation Tricarboxylic acid cycle
Molecular function	Lyase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbon utilization by fixation of carbon dioxide Inferred from electronic annotation. Source: HAMAP tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoenolpyruvate carboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 1023	1023	Phosphoenolpyruvate carboxylase HAMAP MF_00595		PRO_1000025547
Sites
	Active site	199	1	By similarity
	Active site	669	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3MB82-1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: B6D991E1400700B0	FASTA	1,023	117,485
	10 20 30 40 50 60 MGSVLYSLSE SANLYPASEL FLRHRLQIVE ELWESVLRQE CGQNMVDLLR QLRDLCSPEG 70 80 90 100 110 120 QATKDQAVSA VKLIEQLNIN EAIRAARAFA LYFQLINIIE QEYEQRQQLT RYSDLEAETA 130 140 150 160 170 180 PLNGSENITS SSNHNEDDVI FNRGLGTDFL GKNWTNRGQG KQKGTFAALF PLLSKLNVPP 190 200 210 220 230 240 QQIQRLISQL DVRLVFTAHP TEIVRHTIRD KQRQVVDLLQ QLDEVENRAK EGGGYPWEAG 250 260 270 280 290 300 EIREKLLEEI RLWWRTDELH QFKPTVLDEV DYALHYFQEV LFDGIPQLYK RFKYALNQTF 310 320 330 340 350 360 SWLEPPSKDF CSFGSWVGSD RDGNPSVTPE ITWQTACYQR KMVLERYIKS VKQLIELLSI 370 380 390 400 410 420 SMHWSDVLPD LLESLELDQS QLSEVYDALA LRYRQEPYRL KLAYVLKRLE NTRDRNLALY 430 440 450 460 470 480 KGETPTNEDS PMYRSGAEFL AELRLIQHNL TETGLSCREL DNLICQVEIF DFNLTKLDIR 490 500 510 520 530 540 QESTRHSDAL NEILDYLQLL PQPYNDLSEE QRVAWLTTEL QTRRPLISSE LPFSDKTNDV 550 560 570 580 590 600 IKTFRVVRSL QQEFGINICQ TYIISMCRQV SDVLEVLLLA KEARLFDPAI AVGTIQVVPL 610 620 630 640 650 660 FETVEDLQRS RSVMRQLFEL PLYRALLAGG YKSTEVKVPS PESTPLPTPH SVLTPDLQEV 670 680 690 700 710 720 MLGYSDSNKD SGFLSSNWEI HKAQKSLQKI AEEYGVNLRI FHGRGGSVGR GGGPAHEAIL 730 740 750 760 770 780 AQPGHSINGR IKITEQGEVL ASKYSLLDLA LYNLETITTA VIQASLLRTG FDDIEPWNEI 790 800 810 820 830 840 MEELAARSRQ HYRGLIYEQP DFIDFFHQVT PIEEISQLQI SSRPARRPSG KKDLSSLRAI 850 860 870 880 890 900 PWVFSWTQTR FLLPSWYGVG TALQEFFNEE PEEHLKLMRY FYVKWPFFKM VISKVEMTLA 910 920 930 940 950 960 KVDMQMAGHY VQELSDPEDK SRFEKVFEQI ANEYYLTRDL VLKITDHSRL LDGDPVLQRS 970 980 990 1000 1010 1020 VQLRNGTIVP LGFIQVSLLK RLRQSKNNNA TSGVIHSRYS KGELLRGALL TINGIAAGMR NTG

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000117 Genomic DNA. Translation: ABA21754.1.
RefSeq	YP_322649.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3680275.
GenomeReviews	Gene locus Ava_2134 in contig CP000117_GR.
KEGG	ava:Ava_2134.
NMPDR	fig|240292.3.peg.1731.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3MB82.
OMA	Q3MB82. KITEQGE.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_2134-MON.
Family and domain databases
HAMAP	MF_00595. [Tree]
InterPro	IPR001449. PEP_COase. IPR018129. PEP_COase_AS. IPR015813. Pyrv/PenolPyrv_Kinase_cat. [Graphical view]
Gene3D	G3DSA:3.20.20.60. Pyrv/PenolPyrv_Kinase_cat. 1 hit.
Pfam	PF00311. PEPcase. 1 hit. [Graphical view]
PRINTS	PR00150. PEPCARBXLASE.
PROSITE	PS00781. PEPCASE_1. 1 hit. PS00393. PEPCASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

CAPP_ANAVT

Accession

Primary (citable) accession number: Q3MB82

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2005
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)