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Q3MAV9 (AROA_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 55. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-phosphoshikimate 1-carboxyvinyltransferase
EC=2.5.1.19
Alternative name(s):
5-enolpyruvylshikimate-3-phosphate synthase
Short name=EPSP synthase
Short name=EPSPS
Gene names
Name:aroA
Ordered Locus Names:Ava_2259
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length426 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. HAMAP MF_00210

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7. HAMAP MF_00210

Subunit structure

Monomer By similarity. HAMAP MF_00210

Subcellular location

Cytoplasm By similarity HAMAP MF_00210.

Sequence similarities

Belongs to the EPSP synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   Molecular functionTransferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-phosphoshikimate 1-carboxyvinyltransferase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 4264263-phosphoshikimate 1-carboxyvinyltransferase HAMAP MF_00210
PRO_1000012407

Sequences

Sequence LengthMass (Da)Tools
Q3MAV9 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: 78D780B9C7F0D987

FASTA42646,690
        10         20         30         40         50         60 
MDTIAIPALN RPVDATVEIP GSKSITNRAL LVAALAQGDS TLENALFSED SEYFAKCVEQ 

        70         80         90        100        110        120 
LGIPITLNPH LAQIQVSGKG GDIPAKQADL FVGLAGTAAR FITALVALGN GEYRLDGVPR 

       130        140        150        160        170        180 
MRERPMGDLV TVLQNSGIKI NFEGNSGFMP YTIYGQQFAG GHFRLKANQT SQQLSALLMI 

       190        200        210        220        230        240 
APYAQQDTTI EVEGTLVSQS YVKMTCRLMA DFGVDVTQTD DNQFHIKAGQ RYQARHYTIE 

       250        260        270        280        290        300 
PDASNASYFF AAAAVTGGRV RVNHLTKQSC QGDILWLNVL EQMGCQVLEG EDYTEVIGPE 

       310        320        330        340        350        360 
QLQGIDVDMN DMSDLVQTLG AIAPYANSPV IIRNVEHIRY KETERIRAVV TELRRLGVKV 

       370        380        390        400        410        420 
EEFADGMKIE PTPINPAAIE TYHDHRMAMA FAVTGLKTPG IVIQDPGCTA KTFPDYFTRF 


FKMIGQ

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA21877.1.
RefSeqYP_322772.1. NC_007413.1.

3D structure databases

HSSPHSSP built from PDB template 2AA9 based on UniProtKB P0A6D3.
ProteinModelPortalQ3MAV9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3MAV9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3679004.
GenomeReviewsGene locus Ava_2259 in contig CP000117_GR.
KEGGava:Ava_2259.
NMPDRfig|240292.3.peg.2526.
PATRIC35425307. VBIAnaVar43351_3204.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0128.
HOGENOMHBG646626.
OMAGADIEWG.
PhylomeDBQ3MAV9.
ProtClustDBPRK02427.

Enzyme and pathway databases

BioCycAVAR240292:AVA_2259-MONOMER.

Family and domain databases

HAMAPMF_00210. EPSP_synth.
[Tree]
InterProIPR001986. Enolpyruvate_Tfrase_dom.
IPR006264. EPSP_synthase.
IPR023193. EPSP_synthase_CS.
IPR013792. RNA3'P_cycl/enolpyr_Trfase_a/b.
[Graphical view]
Gene3DG3DSA:3.65.10.10. EPSP_synthase. 2 hits.
KOK00800.
PfamPF00275. EPSP_synthase. 1 hit.
[Graphical view]
PIRSFPIRSF000505. EPSPS. 1 hit.
SUPFAMSSF55205. RNA3'_cycl/enolpyr_transf_A/B. 1 hit.
TIGRFAMsTIGR01356. AroA. 1 hit.
PROSITEPS00104. EPSP_SYNTHASE_1. 1 hit.
PS00885. EPSP_SYNTHASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameAROA_ANAVT
AccessionPrimary (citable) accession number: Q3MAV9
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2005
Last modified: January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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