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Reviewed, UniProtKB/Swiss-Prot Q3MAP7 (MURB_ANAVT)

Last modified November 3, 2009. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    UDP-N-acetylenolpyruvoylglucosamine reductase
    EC=1.1.1.158
Alternative name(s):
    UDP-N-acetylmuramate dehydrogenase
Gene names
Name: murB
Ordered Locus Names: Ava_2321
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

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Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Cell wall formation By similarity.

Catalytic activity

UDP-N-acetylmuramate + NADP+ = UDP-N-acetyl-3-O-(1-carboxyvinyl)-D-glucosamine + NADPH. HAMAP MF_00037

Cofactor

FAD By similarity.

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00037

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the murB family.

Contains 1 FAD-binding PCMH-type domain.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 331331UDP-N-acetylenolpyruvoylglucosamine reductase HAMAP MF_00037
PRO_1000002861

Regions

Domain54 – 221168FAD-binding PCMH-type

Sites

Active site2001 By similarity
Active site2511Proton donor By similarity
Active site3211 By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q3MAP7-1 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: DD170A1362E767AC

FASTA33135,866
        10         20         30         40         50         60 
MKISQAVGNA CTVPASNVET HNNNPSRESK IIYLPGTNCE IKSQALLSAF TSYRVGGAAE 

        70         80         90        100        110        120 
LYVAPRNIEA LQASLKYAQE HNLRVTTLGA GSNLLVSDRG ISGLVIATRH LRYNRFDHQT 

       130        140        150        160        170        180 
GQVTVAAGES IPSLAWEIAK LGWQGFEWAV GIPGTVGGAV VMNAGAHNSC IADILVSAQV 

       190        200        210        220        230        240 
LSPDGTIETL TPEELGYGYR TSLLQGSNRV VTQATFQLQP GFDPAYITAT TREHKQMRLT 

       250        260        270        280        290        300 
TQPYNFPSCG SVFRNPKPYS AGWLIEQSGL KGYQIGGAQV AHLHANFIVN RGGAKANDIF 

       310        320        330 
CLIRHIQQEV QERWSILLEP EVKMLGEFQA A

« Hide

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References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000117 Genomic DNA. Translation: ABA21939.1.
RefSeqYP_322834.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ3MAP7.

Genome annotation databases

GeneID3683591.
GenomeReviewsGene locus Ava_2321 in contig CP000117_GR.
KEGGava:Ava_2321.
NMPDRfig|240292.3.peg.201.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ3MAP7.
OMAGPADILI.

Enzyme and pathway databases

BioCycAVAR240292:AVA_2321-MON.

Family and domain databases

HAMAPMF_00037.
[Tree]
InterProIPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR003170. MurB.
IPR011601. MurB_C.
IPR006094. Oxid_FAD_bind_N.
[Graphical view]
Gene3DG3DSA:3.30.465.10. CO_DH_flavoprot_FAD-bd_sub2. 1 hit.
G3DSA:3.30.43.10. FAD-binding_2_sub1. 1 hit.
G3DSA:3.90.78.10. MurB_C. 1 hit.
PANTHERPTHR21071. MurB. 1 hit.
PfamPF01565. FAD_binding_4. 1 hit.
PF02873. MurB_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR00179. murB. 1 hit.
PROSITEPS51387. FAD_PCMH. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameMURB_ANAVT
AccessionPrimary (citable) accession number: Q3MAP7
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2005
Last modified: November 3, 2009
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents