Reviewed, UniProtKB/Swiss-Prot Q3MAB0 (IDI2_ANAVT)

Names and origin

Protein names

Recommended name:
    Isopentenyl-diphosphate delta-isomerase
      Short name=IPP isomerase
    EC=5.3.3.2
Alternative name(s):
    Isopentenyl pyrophosphate isomerase

Gene names

Name:	fni
Ordered Locus Names:	Ava_2461

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	350 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) By similarity.
Catalytic activity	Isopentenyl diphosphate = dimethylallyl diphosphate. HAMAP MF_00354
Cofactor	FMN By similarity. NADPH By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the IPP isomerase type 2 family.

Ontologies

Keywords
Biological process	Isoprene biosynthesis
Cellular component	Cytoplasm
Ligand	FMN Flavoprotein NADP
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	isoprenoid biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	FMN binding Inferred from electronic annotation. Source: InterPro isopentenyl-diphosphate delta-isomerase activity Inferred from electronic annotation. Source: HAMAP oxidoreductase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 350	350	Isopentenyl-diphosphate delta-isomerase HAMAP MF_00354		PRO_0000229493

Sequences

	Sequence		Length	Mass (Da)
	Q3MAB0-1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: A6F6C859839DF334	FASTA	350	37,631
	10 20 30 40 50 60 MNSPATSNSA QTQSRKADHI RICLEEDVQF RATTNGLERY RFNHSCLPEI DRNDIDLSAT 70 80 90 100 110 120 FLGKKLNAPL LISSMTGGTE QAGIINQRLA RLAQDYKFAM GVGSQRVALE KPQVADTFAI 130 140 150 160 170 180 RKYAPDVLLF ANVGAVQLNY KYGLDECLRI IDMLEADALI LHINPLQECI QPKGDVNFQG 190 200 210 220 230 240 LLDKISELCE ELSVPVIAKE VGNGISGAMA KKLIAAGVQV IDVAGAGGTS WAKVEGERAE 250 260 270 280 290 300 NSMQRRLGRT FADWGIPTAE CITSVRAIAP HIPLIASGGL RDGLDIAKAI ALGADIAGLA 310 320 330 340 350 MPFLQAAVES EAALQELAEV LIAEITTVLF CTGNATLHQL KHSGSLQRLQ

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000117 Genomic DNA. Translation: ABA22076.1.
RefSeq	YP_322971.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3682851.
GenomeReviews	Gene locus Ava_2461 in contig CP000117_GR.
KEGG	ava:Ava_2461.
NMPDR	fig|240292.3.peg.1518.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3MAB0.
OMA	Q3MAB0. AMGVGSQ.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_2461-MON.
Family and domain databases
HAMAP	MF_00354. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR000262. FMN-dep_DH. IPR011179. IPdP_isomerase. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
PANTHER	PTHR10578:SF3. IPdP_isomerase. 1 hit.
Pfam	PF01070. FMN_dh. 1 hit. [Graphical view]
PIRSF	PIRSF003314. IPP_isomerase. 1 hit.
TIGRFAMs	TIGR02151. IPP_isom_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

IDI2_ANAVT

Accession

Primary (citable) accession number: Q3MAB0

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	October 25, 2005
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)