Reviewed, UniProtKB/Swiss-Prot Q3MA33 (TRPF_ANAVT)

Names and origin

Protein names

Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase
      Short name=PRAI
    EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	Ava_2538

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	210 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the trpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 210	210	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000018576

Sequences

	Sequence		Length	Mass (Da)
	Q3MA33-1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 851C3F8FEF805DBB	FASTA	210	22,906
	10 20 30 40 50 60 MRVKICGITQ PQQSVAIASL GATALGFICV PSSPRYVTAA QIWAAVAPLP KNIDKIGVFA 70 80 90 100 110 120 NSSIAEIKQT VIDCGLTGVQ LHGDETPEFC DQLRRSLPQV EILKALRVRS LEHLEQAIIY 130 140 150 160 170 180 TQYINTLLLD AYHPQQLGGT GQTLDWQMLH KFHPSCPWLL AGGLTPDNIL EALSQLNPDG 190 200 210 IDLSSGVERK PGDKDLDKVA LLFEKLGSRN

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000117 Genomic DNA. Translation: ABA22153.1.
RefSeq	YP_323048.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3682423.
GenomeReviews	Gene locus Ava_2538 in contig CP000117_GR.
KEGG	ava:Ava_2538.
NMPDR	fig|240292.3.peg.2019.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3MA33.
OMA	Q3MA33. SKICGIT.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_2538-MON.
Family and domain databases
HAMAP	MF_00135. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPF_ANAVT

Accession

Primary (citable) accession number: Q3MA33

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	October 25, 2005
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)