Reviewed, UniProtKB/Swiss-Prot Q3M9K5 (PPNK2_ANAVT)

Names and origin

Protein names

Recommended name:
    Probable inorganic polyphosphate/ATP-NAD kinase 2
      Short name=Poly(P)/ATP NAD kinase 2
    EC=2.7.1.23

Gene names

Name:	ppnK2
Ordered Locus Names:	Ava_2718

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	306 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus By similarity.
Catalytic activity	ATP + NAD+ = ADP + NADP+. HAMAP MF_00361
Cofactor	Divalent metal ions By similarity.
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the NAD kinase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	ATP-binding NAD NADP Nucleotide-binding
Molecular function	Kinase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	metabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW NAD+ kinase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 306	306	Probable inorganic polyphosphate/ATP-NAD kinase 2 HAMAP MF_00361		PRO_0000229597

Sequences

	Sequence		Length	Mass (Da)
	Q3M9K5-1 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: 92FF532C5F3D15A6	FASTA	306	33,933
	10 20 30 40 50 60 MQLKQVIIAY KARDSQSKRW AELCAKQLEN RNCQVLMGPS GPKDNPYPVF LASASQPIDL 70 80 90 100 110 120 AIVLGGDGTV LTSARHLAPA GIPILGVNVG GHLGFLTESV DEFQDTEKVW DRLFEDRYAI 130 140 150 160 170 180 QRRMMLQAAV YEGHRTNLEP VTERYLGLNE FCVKPASADR MITSILEMEI DGEVVDQYVG 190 200 210 220 230 240 DGLIISTPTG STGYTVSASG PIMHDGMEAI TITPICPMSL SSRPLILPAG SVVSIWPLGD 250 260 270 280 290 300 YDLSTKLWMD GVLATSIWPA HRVDIRMADC RAKFIVLREN NSYYQTLREK LLWAGTRVRY TSTQHN

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000117 Genomic DNA. Translation: ABA22331.1.
RefSeq	YP_323226.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q3M9K5.
Genome annotation databases
GeneID	3682079.
GenomeReviews	Gene locus Ava_2718 in contig CP000117_GR.
KEGG	ava:Ava_2718.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3M9K5.
OMA	KLHWAGS.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_2718-MON.
Family and domain databases
HAMAP	MF_00361. [Tree]
InterPro	IPR017437. ATP-NAD_kinase_PpnK-typ_all-b. IPR002504. ATP_NADK. [Graphical view]
Gene3D	G3DSA:2.60.200.30. ATP-NAD_kinase_PpnK-typ. 1 hit.
PANTHER	PTHR20275. ATP_NADK. 1 hit.
Pfam	PF01513. NAD_kinase. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

PPNK2_ANAVT

Accession

Primary (citable) accession number: Q3M9K5

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	October 25, 2005
Last modified:	November 3, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)