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Protein

Histidine kinase

Gene

Ava_2803

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-2837-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_2803Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiESSSHTN.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3M9C0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLNIPGYTIS EELYDGSRTL VYRAIRQADT LPVVIKLLKN PYPSFSELVQ
60 70 80 90 100
FRNQYTIAKN LNYPGIIATH SLEPLHNGYQ LVMEDFGGIS VKDYFVHNHY
110 120 130 140 150
VASLDKFLQI AIALCDILDI LYRQRIIHKD IKPANILINP ETTQVKLIDF
160 170 180 190 200
SIASLLPRET QTLINPNVLE GTLGYISPEQ TGRMNRGIDH RTDFYSLGAT
210 220 230 240 250
FYELLTGKLP FPSEDAMELV HCHLAKAPTL VHEINLTIPS VLSDIVNKLM
260 270 280 290 300
AKNAEDRYQS ALGLKYDLEK CLVQLQETGK IESFPIAQRD VCDRFIIPDK
310 320 330 340 350
LYGREAEVET LLQAFERVST GNTEMMLVAG FSGIGKTAVV NEVHKPIVRQ
360 370 380 390 400
RGYFIKGKYD QFQRNIPFSA FVQAFRDLMG QLLTESDAQI QQWKSQILAA
410 420 430 440 450
VGENGQVIIE VIPELAGIIG QQPPIIELSG TAAQNRFNLL FQKFVQVFKT
460 470 480 490 500
QEHPLVMFLD DLQWADSASL NLMQLLMSES GGGYLLLIGA YRDNEVSDAH
510 520 530 540 550
PLMFSLAEIR KAQATINTIT LAPLSQSSLN QLVADTLSCS SAIAQPLTQL
560 570 580 590 600
VYQKTKGNPF FSTQFIKAIY EDGLITFNGD EGNWQCDIVG VKESSLSDDV
610 620 630 640 650
VEFMALQLQK LPQTTQNILK FAACIGNKFD LGILAIIWEK SLTETATALW
660 670 680 690 700
KALQEGLILP QSEVYKFYVD REIQDEVKGS QTVTYKFLHD RVQQAAYSLI
710 720 730 740 750
PAEQKQYTHF QIGQLLLQGL SQGEQEERIF DIVNQLNMGL DVITSNEQKQ
760 770 780 790 800
ELAHLNLKAG QKAKLSAAYQ AAYDYCTIGM SVLSPDAWQQ DYPLMYSLHR
810 820 830 840 850
DASEAAYLCG KFDQAEALYA ETLTYAQAPL DQAIVYRIQM TQYQLQGRNA
860 870 880 890 900
EAIAIQRQSL QMLGWTIPTQ PEMIQAGLDA EIATVQQFLE QHTIESILAA
910 920 930 940 950
PKMVDPSIAE MLRILQILFY AAWLDGQSTL ALLALAKMTT LSLQYGNSDM
960 970 980 990 1000
SPFGYAGYGL IANGVFKDCA TAYEFGEMAV QLCEQFDNAD VRGMTNFIFA
1010 1020 1030 1040 1050
ADVHSWSRPI READTYYNNA YQYGMEAGNW LTVGFMMMQS GSDRLTYGKH
1060 1070 1080 1090 1100
LDDLYAIAQN HAAFLHQIKS LDNLDALTAG VLQPIRHLLG LTKTLFTFDD
1110 1120 1130 1140 1150
DDFSEAEYLQ KYANAPYHLS WLYSVKIRHA YLFDQKSTYS DLIPQLSMIE
1160 1170 1180 1190 1200
TTISSHAKVP SSVFYVALMH LALAETATEA SERQHHWQAL LPLETSLKRW
1210 1220 1230 1240 1250
LKACPENIRH KFLLIQAEKA RIKKQKTKAI ELYEQAISQA QANQYGYEEA
1260 1270 1280 1290 1300
LANELAAKFY LDWGKVKIAQ VYMQEACYGY ARWGAKAKAH HLEKTYPQLL
1310 1320 1330 1340 1350
KPILQQQRIN FNPLETITFR GATSSTHTTT TSSTNISEIL DFTSVLKGAQ
1360 1370 1380 1390 1400
AISGCIELDE LIANLTRIIL ENSGAKKSVL ILPLEETWQV KAITSVNQES
1410 1420 1430 1440 1450
SSHTNIQTIL SSQSIEDCQD IPPKIINYVK NTQKPLIIDN CQTDIPGVIG
1460 1470 1480 1490 1500
EYMLEHQPKS VLCTPIIHQG HLVGILYLEN ELTSEVFNSE HLQVVNLLSS
1510 1520 1530 1540 1550
QAAISLENAR LYQKAQQALQ DLQQAQLQIV QSEKMSALGN LVAGVAHEMN
1560 1570 1580 1590 1600
NPLGFIAASL MQAQPIIADI TEHLKLYQEN LPDKIEKIAD HAQEIDLEYI
1610 1620 1630 1640 1650
LEDLPKMIES MTMACERLKN ISTSLRTFSR ADRDYKVPFN IHEGIESTIL
1660 1670 1680 1690 1700
ILKHRLKANE QRPAIEVVTE YADSPMIECF PGQINQVFMN ILANAIDALD
1710 1720 1730 1740 1750
EANMGRSFAE IQANHNKIMI RTLLENQQVK ITIADNGKGM SEEVKAKIFD
1760 1770 1780 1790 1800
HLFTTKMVGK GTGLGLAIAQ SIVVEKHGGT LTVNSTLGEG TEFVISLPIL

DESQN
Length:1,805
Mass (Da):202,399
Last modified:October 25, 2005 - v1
Checksum:i1FF27416AA647212
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA22416.1.
RefSeqiYP_323311.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA22416; ABA22416; Ava_2803.
GeneIDi3681639.
KEGGiava:Ava_2803.
PATRICi35426519. VBIAnaVar43351_3804.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA22416.1.
RefSeqiYP_323311.1. NC_007413.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA22416; ABA22416; Ava_2803.
GeneIDi3681639.
KEGGiava:Ava_2803.
PATRICi35426519. VBIAnaVar43351_3804.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiESSSHTN.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-2837-MONOMER.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3M9C0_ANAVT
AccessioniPrimary (citable) accession number: Q3M9C0
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: March 4, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.