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Protein

Histidine kinase

Gene

Ava_2845

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

Catalytic activityi

ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.SAAS annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-2880-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_2845Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_2845.

Structurei

3D structure databases

ProteinModelPortaliQ3M978.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiVPIFHFY.
OrthoDBiEOG6B35XT.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR001610. PAC.
IPR000014. PAS.
IPR000700. PAS-assoc_C.
IPR013655. PAS_fold_3.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF08447. PAS_3. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00086. PAC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50113. PAC. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3M978-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIATQVSIPG YIVHEQLYDG SRTFVYRSVK ETDNKPVVIK LLKNHYPSFS
60 70 80 90 100
ELVQFRNQYT IAKNLNYPGI IRTYSLESFQ NGYILVMEDF GGISLKDYFF
110 120 130 140 150
KNYVSSLDEF LQIAIALCNT LDILYKERII HKDIKPSNIL INPETKQVKL
160 170 180 190 200
IDFSIASLLP RETQTLVNPN VLEGTLAYIS PEQTGRMNRG IDYRTDFYSL
210 220 230 240 250
GVTFYELLTR ELPFPANEPM EVVHCHIAKT APLAHEVNPQ IPPILSAIVS
260 270 280 290 300
KLMAKNVEDR YQSALGLKYD LENCLSQLQA TGKIESFKIA QRDVCDRFII
310 320 330 340 350
PDKLYGREAQ IEMLLQAFDR VSLGATEMML VAGFSGIGKT AVVNEVHKPI
360 370 380 390 400
VRQRGYFIKG KFEQFQRNIP FSAFVQAFRN LIGKLLTESN SQIQQWKVQI
410 420 430 440 450
LEALGENGQV IIDVIPELEL IIGQQPPTKD LSGSAAQNRF NLLFQKFTHV
460 470 480 490 500
FTSKEHPLVI FLDDLQWADL ASLNLMQILI ADTEYLLLIG AYRDNEVSPS
510 520 530 540 550
HPLMFTLGEI KKLPSIINTI TLTPLSQIRI NQLVADTLKC TEALAWNLSQ
560 570 580 590 600
LVYQKTQGNP FFSTQFLKAL HQENLIQFNF FEGYWQCDIT AINQQSLTSD
610 620 630 640 650
VVEFMVFQLQ RLSASTQDVL KLAACIGNYF DLSILAIVSG QTEVEIATDL
660 670 680 690 700
WQALQEGLIL PTSNIYKFYQ QDTLLDHQRI TNDNGKRVFT YKFLHDRVQQ
710 720 730 740 750
AAYSLIPNNQ KAVTHLKIGE LLRQNLSQIE QEEKLFDIVG HLNRGQELIT
760 770 780 790 800
QLSEREALAK LNLQAGVKAR NSTAYAAATE YLQLGIELLQ TNCWQTQYEL
810 820 830 840 850
ALNLHIAAVE VAYLNGDFEE MEKIAAMVLR SAQTILDKVK IYTIQIAAQT
860 870 880 890 900
TQSQMLEAIA IGTDALSQLG VEFPREPDEA EIAKVLQAIT NQLQSRQIGE
910 920 930 940 950
LVDLPVMTDP TSVAAMQLLG RLFSPIFVGI PGLLPILSAK MVSLSLQFGN
960 970 980 990 1000
TPTSTVGYAI HGLVMCAVLQ EVETGYSFGK LALSLLERFN LPEYKSMTLH
1010 1020 1030 1040 1050
LFGDFIQHHR ETLQATKLTL KDSYRIGMDT GDFLRAGYSI VGYSQVRLFS
1060 1070 1080 1090 1100
GVELDICESE LATYSAALAQ VKQFSPQVYL NLTWQTVKNL REPVNQPDCL
1110 1120 1130 1140 1150
IGSAYDETQM FPKHFQDREL TAISTAYIAK LMLAYLWGNY SPAISYIKQI
1160 1170 1180 1190 1200
KLYLMAVSGL ICVPIFHFYA ALTYLAIFRT QSKPEQAEIL AQIATHQTRL
1210 1220 1230 1240 1250
HHSAQNAPMN HLHKWYLVEA EKQRVLGYYY EAGDRYDRAI AGAKANGYIQ
1260 1270 1280 1290 1300
EEGLANELAA KFYLDWGREK AAIWYLQEAY YCYAKWGAKA KVADLERRYP
1310 1320 1330 1340 1350
QLLAPILQQS RSTLSTNETI FTVGTVTKSS SSVSSSSSNV SDTLDLTAIL
1360 1370 1380 1390 1400
KASQAISGEI ELEKLLSSLL RIIIENAGAD KCVLMLLQDN HLLIQGSITQ
1410 1420 1430 1440 1450
GYKPIMLPSL PVEDSLEIPH KLIYKVKHSQ HTVVLLDATA DTTLANDPYI
1460 1470 1480 1490 1500
IRQKPLSILC SPILYQGKLL GILYLENNLV RGAFTSDRVQ LLNLLCTQVA
1510 1520 1530 1540 1550
ISLENAQLYQ RSQENAQQLE RSLEKLRLSE ARFQKLANNV PGIIYQIRIK
1560 1570 1580 1590 1600
ADGSASIPYV SSGCQTLYEI AAEDFMSGKY SLRDFEHPDD RAKAFQIVVE
1610 1620 1630 1640 1650
SAKNLTPFQH EWRIITPNGN IKWVKAASQP ERGEDGEIVW DGILIEISDL
1660 1670 1680 1690 1700
KQAELDLQQA QLQIIQSEKM SALGNLVAGV AHEMNNPLGF IAASLKQAKP
1710 1720 1730 1740 1750
TFADILEHLK IYQETLPDKT EEILDHESEI DLEYTIEDLP KMLDSMTIAC
1760 1770 1780 1790 1800
DRLKNISTSL RTFSRADRDY KVPFNLHEGI DSTILILKHR LKSNEQRPAI
1810 1820 1830 1840 1850
EVITNYGNLP QLECFPGQLN QVFMNILVNA IDALDESNHG RNFEEIKSHP
1860 1870 1880 1890 1900
NQITITTSIA DKSVKISIAD NGKGMSEEVK HKIFDHLFTT KGVGKGTGLG
1910 1920 1930
LAIAKQIVVE SHGGQLKCNS ALGEGTEFII EIPV
Length:1,934
Mass (Da):217,446
Last modified:October 25, 2005 - v1
Checksum:iE068C0BE14CA7B5C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA22458.1.
RefSeqiWP_011319598.1. NC_007413.1.
YP_323353.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA22458; ABA22458; Ava_2845.
KEGGiava:Ava_2845.
PATRICi35426623. VBIAnaVar43351_3855.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA22458.1.
RefSeqiWP_011319598.1. NC_007413.1.
YP_323353.1. NC_007413.1.

3D structure databases

ProteinModelPortaliQ3M978.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240292.Ava_2845.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA22458; ABA22458; Ava_2845.
KEGGiava:Ava_2845.
PATRICi35426623. VBIAnaVar43351_3855.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiVPIFHFY.
OrthoDBiEOG6B35XT.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-2880-MONOMER.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR001610. PAC.
IPR000014. PAS.
IPR000700. PAS-assoc_C.
IPR013655. PAS_fold_3.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF08447. PAS_3. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
SM00086. PAC. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55785. SSF55785. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50113. PAC. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3M978_ANAVT
AccessioniPrimary (citable) accession number: Q3M978
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: May 27, 2015
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.