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Q3M935 (MURG_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase
EC=2.4.1.227
Alternative name(s):
Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase
Gene names
Name:murG
Ordered Locus Names:Ava_2890
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033

Catalytic activity

UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033

Pathway

Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033

Subcellular location

Cell inner membrane; Peripheral membrane protein By similarity HAMAP MF_00033.

Sequence similarities

Belongs to the glycosyltransferase 28 family. MurG subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 357357UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase HAMAP MF_00033
PRO_1000002614

Sequences

Sequence LengthMass (Da)Tools
Q3M935 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: 141647CC38F093A1

FASTA35737,822
        10         20         30         40         50         60 
MVNAPIKLLI AASGTGGHLF PAIALAEKLP DYEIEWLGVP NRLETQLVPK QYPLNTIAVE 

        70         80         90        100        110        120 
GFQQGLGLSS LVILGKLIGS ILKVRRLLKQ GNFQGVVTTG GYIAGPAVIA ARSLGLPVIF 

       130        140        150        160        170        180 
HESNALPGKV TRFFGPWCSV VALGFDVAAK YLPRATNVCV GTPVRSQFLN LSNNSQLDLA 

       190        200        210        220        230        240 
IPGGVPVIVV FGGSQGAVAV NQLVRQAAPA WFEAGAYVVH LTGDRDPDVD SLKHPQYIEL 

       250        260        270        280        290        300 
PFYDNMAALL QRASLAISRS GAGSLTELAV CGTPAILIPY PFAAEDHQSY NAEVFTKAGA 

       310        320        330        340        350 
ALSFKQSALT AELLQNQVLN LLQSPPELAK MGENAKAIAV PDSADKLAVL VREVVER

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA22501.1.
RefSeqYP_323396.1. NC_007413.1.

3D structure databases

ProteinModelPortalQ3M935.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3M935.

Protein family/group databases

CAZyGT28. Glycosyltransferase Family 28.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3681454.
GenomeReviewsGene locus Ava_2890 in contig CP000117_GR.
KEGGava:Ava_2890.
NMPDRfig|240292.3.peg.1559.
PATRIC35426723. VBIAnaVar43351_3905.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0707.
HOGENOMHBG617076.
OMAEDHQTKN.
PhylomeDBQ3M935.
ProtClustDBCLSK2396759.

Enzyme and pathway databases

BioCycAVAR240292:AVA_2890-MONOMER.

Family and domain databases

HAMAPMF_00033. MurG.
[Tree]
InterProIPR006009. GlcNAc_MurG.
IPR004276. Glyco_trans_28.
IPR007235. Glyco_trans_28_C.
[Graphical view]
KOK02563.
PANTHERPTHR21015:SF22. PTHR21015:SF22. 1 hit.
PfamPF04101. Glyco_tran_28_C. 1 hit.
PF03033. Glyco_transf_28. 1 hit.
[Graphical view]
TIGRFAMsTIGR01133. MurG. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMURG_ANAVT
AccessionPrimary (citable) accession number: Q3M935
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: October 25, 2005
Last modified: January 25, 2012
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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