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Protein

Histidine kinase

Gene

Ava_3535

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. calmodulin-dependent protein kinase activity Source: UniProtKB-EC
  3. phosphorelay sensor kinase activity Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-3581-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_3535Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_3535.

Structurei

3D structure databases

ProteinModelPortaliQ3M794.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiVADTLHC.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF13492. GAF_3. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3M794-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MATQQYSNPI ITGYQISSQL YAGSKTRVYR AIREQDQLPV VIKVLASDYP
60 70 80 90 100
NFQELLQFRN QYTISKNLNV TGIIRPLSLE TYGNGYILVM EDTGGIALRE
110 120 130 140 150
YIKTAPLPLV EFLAIAIQIT SILQELHLNR VIHKDIKPAN ILIHPQTKQV
160 170 180 190 200
HLIDFSIASL LPKETQEIRS PNVLEGTLAY ISPEQTGRMN RGIDYRSDFY
210 220 230 240 250
SLGVTLYELL MGELPFSSDD PMELVYCHIA KTPIALGHQQ HIPLVLSDII
260 270 280 290 300
MKLMAKNAED RYQSALGLKH DLETCLYQCK NNGKITAFEI GKRDMCDRFL
310 320 330 340 350
IPEKLYGRET EVKVLLQAFE RVTKGKSEMM LVAGFSGIGK TAVVNEVHKP
360 370 380 390 400
ITRQQGYFIK GKFDQFNRNL PLSAFVQALR DLMGQLLSES DSQLSKWRTK
410 420 430 440 450
ILDTVGNNGQ VLIEVIPELE IIIGKQHPAP ELSGIAAQNR FNLLFQKFIA
460 470 480 490 500
IFSTPKHPLV MFLDDLQWAD TGSLQLIKLL MEDQSYLLLL GAYRDNEVHT
510 520 530 540 550
AHPLILTVEE LKKAGKTVNK ITLASLTLCD TNHLVADTLH CQAERSHPLT
560 570 580 590 600
ELIERKTKGN PFFITQFLKA LHEDQLITFN RHQGYWECDI TQINELSLTD
610 620 630 640 650
DVVKFMAQKL QKFPSKTQDV LKLAACIGNS FDLNTLAIVL EKSAADTADA
660 670 680 690 700
LWKALQEGLI LPQSEVYKFY LDHDRQDAHV NNSQNVEYRF LHDRVQQAAY
710 720 730 740 750
SLIPQDQKQA THYQIGQLLL KQISPVAREE RIFELVNQLN YGVALITQQT
760 770 780 790 800
ERDELAQLNL TACRKARSAT AYQAAHEYIT VGLLLLGEKA WQHQYEITLH
810 820 830 840 850
LHEFAAEVAS LRGDFAQMEQ FINIVTAQAH TLIEQVNVYR IRIQAYISQN
860 870 880 890 900
KFAEAIAIAQ KILQQLGVTF AEATTPAVIQ QEIQEIRELI GDRAIADLVH
910 920 930 940 950
LPIITDEEKV AIVQIASSIM TVAYLSGSPL FPLITLLLVK ISIQYGNTPA
960 970 980 990 1000
TGYIYSTYGV LLCNVLQDVD TATEFGQLAL QIVSKVDAKA TQPQVLLVLA
1010 1020 1030 1040 1050
LYILQRKSHV QEILPLLQKG YAIALEVGNL EFAGHHAHNF CSHSFWCGQH
1060 1070 1080 1090 1100
LATLQEDARA YSNELEQLNQ ITTANYVRIY WQSTLNLLGF AVHPTILSGE
1110 1120 1130 1140 1150
ALQEQEFIPL LIAANDGYGL YIFYLYKLML CYLFGEIETA KSITIKIKDH
1160 1170 1180 1190 1200
LMAAAGLFCE PIFYLYDSLI ALAQLRQNSE EVSATLQYVA ENQAKLQRWA
1210 1220 1230 1240 1250
QYAPMNHQHK LDLVAAERYR VLGEKTSAIE YYDHAISGAK KSQYIQEEAL
1260 1270 1280 1290 1300
SNELAAKFYL DWGKDKVAQI YMQEAYYCYA RWGAKAKIDN LEKLYPQLLK
1310 1320 1330 1340 1350
PILQRRQLNL NPLETIAPIN RNTIAVPTDT AGTSSTSISD ILDFTSVLKA
1360 1370 1380 1390 1400
AQAISSTIEL EELIVNLTKI ILEISGAKKI VLILPQDNAW YVRAITFISY
1410 1420 1430 1440 1450
ENKPEGKIQN ILLLQPIDTC KHIPGTIINY VKNTLETLVI DNYQIDIPGL
1460 1470 1480 1490 1500
IDQYLLKHQP KSVLCQPIIK QSNLLGILYL ENQITSGVFT LERLQVINLL
1510 1520 1530 1540 1550
SSQAAISLEN ACLYQKAQQA LQDLQAAQLQ IIQSEKMSAL GNLVAGVAHE
1560 1570 1580 1590 1600
MNNPLGFITA TLKQAKPTIA DIAEHLRLYQ ANFPNKSAEI INHAEEIDLD
1610 1620 1630 1640 1650
YSLEDLPKMI DAMVMASDRL KNISTSLRTF SRADTDHKVS FNVHEGIDST
1660 1670 1680 1690 1700
ILILKHRLKA NEQRPAIEVI TDYGNLPQIE CFPGQLNQVF MNILANAIDA
1710 1720 1730 1740 1750
LEATNKGQTL EEIKAHPHQI TITTTVNNDQ VKIIIADNGI GMDEQVKQKI
1760 1770 1780 1790 1800
FDHLFTTKAV GKGTGLGLAI ARQIVVEKHN GSLFVNSQLG AGTEFVITLP

IITR
Length:1,804
Mass (Da):202,826
Last modified:October 25, 2005 - v1
Checksum:i266494E6E703A642
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA23142.1.
RefSeqiYP_324037.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA23142; ABA23142; Ava_3535.
GeneIDi3679559.
KEGGiava:Ava_3535.
PATRICi35428203. VBIAnaVar43351_4634.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA23142.1.
RefSeqiYP_324037.1. NC_007413.1.

3D structure databases

ProteinModelPortaliQ3M794.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240292.Ava_3535.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA23142; ABA23142; Ava_3535.
GeneIDi3679559.
KEGGiava:Ava_3535.
PATRICi35428203. VBIAnaVar43351_4634.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiVADTLHC.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-3581-MONOMER.

Family and domain databases

Gene3Di3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF13492. GAF_3. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3M794_ANAVT
AccessioniPrimary (citable) accession number: Q3M794
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: February 4, 2015
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.