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Q3M781 (Q3M781_ANAVT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 35. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ppa HAMAP MF_00209
Ordered Locus Names:Ava_3548
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length169 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209 EMBL ABA23155.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding641Magnesium 1 By similarity HAMAP MF_00209
Metal binding691Magnesium 1 By similarity HAMAP MF_00209
Metal binding691Magnesium 2 By similarity HAMAP MF_00209
Metal binding1011Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
Q3M781 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: 17A027E16C229C33

FASTA16918,961
        10         20         30         40         50         60 
MDLSRIPAQP KPGVINILIE IAGGSQNKYE FDKDLEAFAL DRVLYSSVKY PYDYGFVPNT 

        70         80         90        100        110        120 
LADDGDPLDG MVIIDEPTFP GCVIAARPIG FLEMIDGGDR DEKILAVPDK DPRYAHVKSL 

       130        140        150        160 
NDVAPHRLDE IAEFFRSYKN LEKKVTQILG WQDVDQVKAL VDKSIKAYK

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References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA23155.1.
RefSeqYP_324050.1. NC_007413.1.

3D structure databases

ProteinModelPortalQ3M781.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3M781.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3679572.
GenomeReviewsGene locus Ava_3548 in contig CP000117_GR.
KEGGava:Ava_3548.
NMPDRfig|240292.3.peg.4388.
PATRIC35428235. VBIAnaVar43351_4650.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0221.
HOGENOMHBG529150.
OMAPNDFNVI.
PhylomeDBQ3M781.
ProtClustDBCLSK895996.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ3M781_ANAVT
AccessionPrimary (citable) accession number: Q3M781
Entry history
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: December 14, 2011
This is version 35 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info