Q3M6T3 (FBSB_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase
Short name=FBPase class 2/SBPase
EC=3.1.3.11
EC=3.1.3.37

Gene names

Ordered Locus Names:

Ava_3697

Organism

Anabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]

Taxonomic identifier

240292 [NCBI]

Taxonomic lineage

Bacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length	345 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the hydrolysis of fructose 1,6-bisphosphate (Fru 1,6-P2) and sedoheptulose 1,7-bisphosphate (Sed 1,7-P2) to fructose 6-phosphate and sedoheptulose 7-phosphate, respectively By similarity.
Catalytic activity	D-fructose 1,6-bisphosphate + H2O = D-fructose 6-phosphate + phosphate. Sedoheptulose 1,7-bisphosphate + H2O = sedoheptulose 7-phosphate + phosphate.
Cofactor	Manganese By similarity.
Pathway	Carbohydrate biosynthesis; Calvin cycle.
Subunit structure	Homotetramer By similarity.
Sequence similarities	Belongs to the FBPase class 2 family.

Ontologies

Keywords
Biological process	Calvin cycle Carbohydrate metabolism
Ligand	Manganese Metal-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycerol metabolic process Inferred from electronic annotation. Source: InterPro reductive pentose-phosphate cycle Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	fructose 1,6-bisphosphate 1-phosphatase activity Inferred from electronic annotation. Source: EC metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW sedoheptulose-bisphosphatase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 345	345	D-fructose 1,6-bisphosphatase class 2/sedoheptulose 1,7-bisphosphatase		PRO_0000342709
Regions
	Region	100 – 102	3	Substrate binding By similarity
	Region	176 – 178	3	Substrate binding By similarity
	Region	198 – 200	3	Substrate binding By similarity
Sites
	Metal binding	33	1	Manganese 1 By similarity
	Metal binding	57	1	Manganese 1 By similarity
	Metal binding	97	1	Manganese 2 By similarity
	Metal binding	100	1	Manganese 2 By similarity
	Metal binding	225	1	Manganese 2 By similarity
	Binding site	131	1	Substrate By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3M6T3 [UniParc]. Last modified October 25, 2005. Version 1. Checksum: DD4BE8B90C900FF8	FASTA	345	36,751
	10 20 30 40 50 60 MENTLGLEII EVVEQAAIAS AKWMGKGEKN TADQVAVEAM RERMNKIYMR GRIVIGEGER 70 80 90 100 110 120 DDAPMLYIGE EVGICTQPNA DQLCNPDELV EIDIAVDPCE GTNLVAYGQP GSMAVLAISE 130 140 150 160 170 180 KGGLFAAPDF YMKKLAAPPA AKGKVDINKS ATENLKILSE CLDRAIDELV VVVMKRDRHQ 190 200 210 220 230 240 GLIKEIRDAG ARVQLISDGD VGAAISCGFA GTNIHALMGI GAAPEGVISA AAMRALGGHF 250 260 270 280 290 300 QGQLIYDPEV VKTGLIGESK EANLERLSSM GINDPDKVYD AHELASGETV LFAACGITSG 310 320 330 340 NLMQGVRFFH GGARTQSLVI SSQSQTARFV DTIHMAGQPK TVQLH

References

[1]

"Complete sequence of Anabaena variabilis ATCC 29413." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P. Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000117 Genomic DNA. Translation: ABA23303.1.
RefSeq	YP_324198.1. NC_007413.1.
3D structure databases
ProteinModelPortal	Q3M6T3.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3M6T3.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3679116.
GenomeReviews	Gene locus Ava_3697 in contig CP000117_GR.
KEGG	ava:Ava_3697.
NMPDR	fig|240292.3.peg.4851.
PATRIC	35428571. VBIAnaVar43351_4818.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1494.
HOGENOM	HBG284837.
OMA	MYDPSAV.
PhylomeDB	Q3M6T3.
ProtClustDB	PRK09479.
Enzyme and pathway databases
BioCyc	AVAR240292:AVA_3697-MONOMER.
Family and domain databases
InterPro	IPR004464. FBPase_class-2/SBPase. [Graphical view]
KO	K11532.
Pfam	PF03320. FBPase_glpX. 1 hit. [Graphical view]
PIRSF	PIRSF004532. GlpX. 1 hit.
TIGRFAMs	TIGR00330. GlpX. 1 hit.
ProtoNet	Search...

Entry information

Entry name

FBSB_ANAVT

Accession

Primary (citable) accession number: Q3M6T3

Entry history

Integrated into UniProtKB/Swiss-Prot:	July 1, 2008
Last sequence update:	October 25, 2005
Last modified:	January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program