ID   G6PI_ANAVT              Reviewed;         528 AA.
AC   Q3M6S3;
DT   04-APR-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Glucose-6-phosphate isomerase;
DE            Short=GPI;
DE            EC=5.3.1.9;
DE   AltName: Full=Phosphoglucose isomerase;
DE            Short=PGI;
DE   AltName: Full=Phosphohexose isomerase;
DE            Short=PHI;
GN   Name=pgi; OrderedLocusNames=Ava_3708;
OS   Anabaena variabilis (strain ATCC 29413 / PCC 7937).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Anabaena.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.;
RT   "Complete sequence of Anabaena variabilis ATCC 29413.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-glucose 6-phosphate = D-fructose 6-
CC       phosphate.
CC   -!- PATHWAY: Carbohydrate biosynthesis; gluconeogenesis.
CC   -!- PATHWAY: Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-
CC       phosphate and glycerone phosphate from D-glucose: step 2/4.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the GPI family.
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DR   EMBL; CP000117; ABA23313.1; -; Genomic_DNA.
DR   RefSeq; YP_324208.1; -.
DR   GeneID; 3678794; -.
DR   GenomeReviews; CP000117_GR; Ava_3708.
DR   KEGG; ava:Ava_3708; -.
DR   NMPDR; fig|240292.3.peg.4861; -.
DR   HOGENOM; Q3M6S3; -.
DR   OMA; Q3M6S3; PYSNDLA.
DR   BioCyc; AVAR240292:AVA_3708-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004347; F:glucose-6-phosphate isomerase activity; IEA:HAMAP.
DR   GO; GO:0006094; P:gluconeogenesis; IEA:HAMAP.
DR   GO; GO:0006096; P:glycolysis; IEA:HAMAP.
DR   HAMAP; MF_00473; -; 1.
DR   InterPro; IPR001672; G6P_Isomerase.
DR   InterPro; IPR018189; Phosphoglucose_isomerase_CS.
DR   PANTHER; PTHR11469; G6P_Isomerase; 1.
DR   Pfam; PF00342; PGI; 1.
DR   PRINTS; PR00662; G6PISOMERASE.
DR   PROSITE; PS00765; P_GLUCOSE_ISOMERASE_1; FALSE_NEG.
DR   PROSITE; PS00174; P_GLUCOSE_ISOMERASE_2; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Cytoplasm; Gluconeogenesis; Glycolysis; Isomerase.
FT   CHAIN         1    528       Glucose-6-phosphate isomerase.
FT                                /FTId=PRO_0000230911.
FT   ACT_SITE    322    322       Proton donor (By similarity).
FT   ACT_SITE    351    351       By similarity.
FT   ACT_SITE    455    455       By similarity.
SQ   SEQUENCE   528 AA;  57743 MW;  2A6A1329F27AFFA0 CRC64;
     MDAKALWQRY QEWLYFHEGL GLYLDVSRMR FDDAFVKSLL PKFDKAFADM AELEKGAIAN
     PDENRMVGHY WLRNPDLAPT PEIAQEIVQT LEQIEAFAEK IQTGAIHPPK ANRFTDIISI
     GIGGSALGPQ FVAEALAPEF PPLKIHFIDN TDPAGIDKIL THLRNNLAST LVLVISKSGG
     TPEPRNGMIE VKKAYAGQNL DFAQYAVAIT STGSNLDKVA QAEGWLATFP MYDWVGGRTS
     EMSSVGLVPA ALQGIDVRAM LEGAKEMDDA TRVPEVKNNP AALLALSWYY SGNGKGEKDM
     VVLPYKDSLL LFSRYLQQLV MESLGKEKDL DGKTVYQGIA VYGNKGSTDQ HAYVQQLREG
     VPNFFATLIE VLEDRNGASP EIDPGVTSGD YLSGFLLGTR QALYENQRDS ITVTIPQVNA
     RTVGALIALY ERTVGLYASL VNINAYHQPG VEAGKKAAAV ILDLQTKVVG LLQKEKTALS
     LEQIAEKIGA ADQVEAIYKI LRHLQANQRG VVFQGNLGQP SSLKVSIS
//