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Q3M4V2 (AROB_ANAVT) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
3-dehydroquinate synthase
EC=4.2.3.4
Gene names
Name:aroB
Ordered Locus Names:Ava_4386
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length363 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate = 3-dehydroquinate + phosphate. HAMAP MF_00110

Cofactor

Divalent metal cations By similarity. HAMAP MF_00110

NAD By similarity. HAMAP MF_00110

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7. HAMAP MF_00110

Subunit structure

Monomer By similarity. HAMAP MF_00110

Subcellular location

Cytoplasm Probable HAMAP MF_00110.

Sequence similarities

Belongs to the dehydroquinate synthase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Aromatic amino acid biosynthesis
   Cellular componentCytoplasm
   LigandNAD
   Molecular functionLyase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processaromatic amino acid family biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular function3-dehydroquinate synthase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 3633633-dehydroquinate synthase HAMAP MF_00110
PRO_0000231061

Sequences

Sequence LengthMass (Da)Tools
Q3M4V2 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: FD37679FEEAA18D2

FASTA36339,290
        10         20         30         40         50         60 
MTSVINVNLP TQSYEIAIAP ASLDQIGQSL AGLKLGKKVL LVSNPTIFKH FGKVAVDSLE 

        70         80         90        100        110        120 
AAGFQVASYC LPAGERYKTL NSIQKLYDIA LENRLERSST MVALGGGVIG DMTGFAAATW 

       130        140        150        160        170        180 
LRGINVVQVP TTLLAMVDSA IGGKTGVNHP HGKNLIGAFH QPRFVLIDPQ VLKTLPVREF 

       190        200        210        220        230        240 
RAGMAEVIKY GVIWDAELFN QLEQSKRLDQ LRYIKPELMD AILTRSCQAK ADVVGKDEKE 

       250        260        270        280        290        300 
GGLRAILNYG HTVGHAVESL TNYRLLKHGE AVGIGMVAAG QIAVNLGLWQ QADADRQNAL 

       310        320        330        340        350        360 
IEKAGLPTKL PAGLDIEGII EALQLDKKVK DGKVRFVLPT QIGVVTVTDE VTSDHIRQVL 


QQM

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA23984.1.
RefSeqYP_324879.1. NC_007413.1.

3D structure databases

ProteinModelPortalQ3M4V2.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3M4V2.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3680572.
GenomeReviewsGene locus Ava_4386 in contig CP000117_GR.
KEGGava:Ava_4386.
NMPDRfig|240292.3.peg.4765.
PATRIC35430179. VBIAnaVar43351_5612.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0337.
HOGENOMHBG632303.
OMAVMALEMS.
PhylomeDBQ3M4V2.
ProtClustDBPRK00002.

Enzyme and pathway databases

BioCycAVAR240292:AVA_4386-MONOMER.

Family and domain databases

HAMAPMF_00110. DHQ_synthase.
[Tree]
InterProIPR016037. DHQ_synth_AroB.
[Graphical view]
KOK01735.
PANTHERPTHR21090:SF1. DHQ_synth_AroB. 1 hit.
PIRSFPIRSF001455. DHQ_synth. 1 hit.
TIGRFAMsTIGR01357. AroB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROB_ANAVT
AccessionPrimary (citable) accession number: Q3M4V2
Entry history
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: October 25, 2005
Last modified: January 25, 2012
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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