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Protein

Histidine kinase

Gene

Ava_4489

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-4549-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_4489Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_4489.

Structurei

3D structure databases

ProteinModelPortaliQ3M4J9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiSIKIQAC.
OrthoDBiEOG6HTNS7.

Family and domain databases

Gene3Di1.10.287.130. 2 hits.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3M4J9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLRLVGYQNL TQIYAGTRTL IYRGIREEDQ KPIVLKILRY EYPSFSELVQ
60 70 80 90 100
FRNQYTITKN LHIPGIIQTY SLENYENSYA LVMEDFGGIS LKDWSNQNSE
110 120 130 140 150
ISLDEFFHIA IQIVTILDGL YRSRVIHKDI KPSNILINPI TKEIRLIDFG
160 170 180 190 200
IASLLPRETQ TLTSPNVLEG TLAYLSPEQT GRMNRGIDYR SDFYSLGVTF
210 220 230 240 250
FELLTGQLPF CCDEPMKLLH CHIAKHPPQV HEINFTIPLA VSNIVFKLMA
260 270 280 290 300
KNAEDRYQSA LGLKHDLETC WRQWKTQGEI SAFELGRRDI CDRFIIPEKL
310 320 330 340 350
YGRQAEVQQL LATFERVSQG HREMILVAGF SGIGKTAIVN EIHKPIVKQS
360 370 380 390 400
GYFIKGKYDQ FQRNIPLSAI VQSFQDLMGQ LLGEANTQIQ DWKTRILAAL
410 420 430 440 450
GEQGQVIIDV IPELQSIIGQ QRQVTELEPS AAQNRFNTLF LKFIQVFTTK
460 470 480 490 500
EHPLVIFLDD LQWADSASLK LIQLLMSQRD NHYLLLIGAY RDNEVSSGHP
510 520 530 540 550
LILTLQDIQK NTEIIETITL KPLELLDLNY LVADTLKCDK EVALPLTQLV
560 570 580 590 600
YQKTQGNPFF SNQFLKYLYN ENLISFNFDK GFWECNIAQV KTLSLTDDVV
610 620 630 640 650
DFMSLQLQKL PEATQNVLKL AACINNHFNL SVLANIYETS LAETAAALWT
660 670 680 690 700
ALREGLIIPT NKVYKFFHDD LSLNNSYNLN NNIEPITVEY KFLHDRVQQA
710 720 730 740 750
AYSLIPEDNK KLTHLKIGQL MLANSTPETR EDKIFEIVNQ FNIGVDLITE
760 770 780 790 800
APARHELAQL NLQAGTKAKS ATAYSAAIEY INLGIGLLTA NRWESQYRLT
810 820 830 840 850
LTLYSEAVEI AYLSTEFQRM ETLAQTVLKN AKILLDKINI YSIKIQACIA
860 870 880 890 900
QNQLLLGIET ALPVLQMLGV HLPPKPTQTD IVKSLQDANS VLMGNTTSDL
910 920 930 940 950
INLPKMDNPE KLAALSILSS MFGAAYNGYP AMFPPLICEE VILSVKYGNA
960 970 980 990 1000
PVSAFAYASY GAILLTFMGD IDAGYEFGNL ALNLIAKLDA KELKAKTFCV
1010 1020 1030 1040 1050
VSCLIKHWKK HLRYTFPLFI EGYHSGWETG DLEWSAWCAF SYTLYLYLAG
1060 1070 1080 1090 1100
TELYSLEQEM SIYSQAIAQF KQKTSLNYLN IYYQSVSCLL GVTENHLQIK
1110 1120 1130 1140 1150
GNIYDEAVML SIHEQASDRP AIYHLYINKL ILCYLFCEYE QAIKNAEIAE
1160 1170 1180 1190 1200
QYLDGVLGIY VVVLLPFYDS LARLALYPHT TVDIQQKILH RVSENQAKIK
1210 1220 1230 1240 1250
QWADYAPMNH QHKFYLVAAE QNRVLGKYLE AMNEYDLAIT KAKENKYLQE
1260 1270 1280 1290 1300
EALANELAAK FYWELGKEKI AQVYFTDAYY AYTRWGSIAK VKDLEQRYSQ
1310 1320 1330 1340 1350
LFSLLSRRSN LIFNPNDTIV KHDSNSSHIH QTQHNTHYYS TTNSNVLDLS
1360 1370 1380 1390 1400
SVIKASQALA SEIKLDKLLS ALMELVIENA GAKKCVLVLL KNEKLVIEAI
1410 1420 1430 1440 1450
ASINQIPIST ILVSIPIAES DEIPISLINY VSHTSQTLVI DDATIEDSFI
1460 1470 1480 1490 1500
SDPYIQKKEP KSLLCTPIIK QGKLMGILYL ENHLTTGAFT SDRLQVINLL
1510 1520 1530 1540 1550
MAQAAISLEN AQLYGQLAEY SQNLELKVEQ RTQELKEKAN QLESALQKLS
1560 1570 1580 1590 1600
STQSQLVQAE KMSSLGQLVA GIAHEINNPV SFIYGNLTYT SEYINSLLDL
1610 1620 1630 1640 1650
INLYQQLYSQ PLPEIQQRIS DIELDFITED LPKMLKSMRF GAQRIEEIVS
1660 1670 1680 1690 1700
SLRTFARLDE AGMKRVDIHS GIDSTLLILQ HRLKFKQNRQ SLPIAVKQNY
1710 1720 1730 1740 1750
GNIPQIYCYA SELNQVFISI LSNAIDALQE DVSNQSGREK QPTITISTEV
1760 1770 1780 1790 1800
KNAESILIRI ADNGPGMSDS VLSKIFDPFF TTKPVGSGTG LGLSISYAIV
1810 1820 1830 1840 1850
VEKHGGQLLC SSGPGMGTEF TIVIPIQTFD TAISRETTNT NSKLRKCDSA
Length:1,850
Mass (Da):209,158
Last modified:October 25, 2005 - v1
Checksum:i85D8A414C6D42DC3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA24087.1.
RefSeqiWP_011321158.1. NC_007413.1.
YP_324982.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA24087; ABA24087; Ava_4489.
GeneIDi3680190.
KEGGiava:Ava_4489.
PATRICi35430413. VBIAnaVar43351_5728.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA24087.1.
RefSeqiWP_011321158.1. NC_007413.1.
YP_324982.1. NC_007413.1.

3D structure databases

ProteinModelPortaliQ3M4J9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240292.Ava_4489.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA24087; ABA24087; Ava_4489.
GeneIDi3680190.
KEGGiava:Ava_4489.
PATRICi35430413. VBIAnaVar43351_5728.

Phylogenomic databases

eggNOGiCOG0642.
HOGENOMiHOG000263148.
OMAiSIKIQAC.
OrthoDBiEOG6HTNS7.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-4549-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 2 hits.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3M4J9_ANAVT
AccessioniPrimary (citable) accession number: Q3M4J9
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: February 4, 2015
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.