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Protein

Histidine kinase

Gene

Ava_4503

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphorelay sensor kinase activity Source: InterPro
  3. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-4563-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_4503Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_4503.

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000263148.
KOiK00903.
OMAiANGASEM.
OrthoDBiEOG6QVRHV.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3M4I5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSATVDTTVL LSGYQLIEQL YHGSKTLVYR GIRRKESVAQ PVVIKLLQRD
60 70 80 90 100
YPSFSELLQF RNQYTIAKNL NIPGVVRPTS LEPYGNSYAL VMEDFGGVSL
110 120 130 140 150
GTYSQTHSLS LVDVLAIALQ LADILHELYQ HRVIHKDIKP ANILIHPESQ
160 170 180 190 200
QVKLIDFSIA SLLPKENEEI KHPNVLEGTL AYIAPEQTGR MNRGVDYRTD
210 220 230 240 250
FYSLGVTLFE LLTGQLPFAG NDPLELVHCH IAKPAPRIDE INSEIPEAIA
260 270 280 290 300
QIVAKLMSKN AEDRYQSALG LKHDLAICLE QLNQTGQIEQ FIIGQRDICD
310 320 330 340 350
RFTIPEKLYG RETEVQTLLD AFARVSNGTS ELLLVAGFSG IGKTAVVNEV
360 370 380 390 400
HKPIVRQRGY FIKGKFDQYN RNIPFSAFVQ AFRDLMGQLL SESDIQLKAW
410 420 430 440 450
KASILEALGD HAHVIIDVIP ELECILGIQP PVAELSGTAA QNRFNLLFQK
460 470 480 490 500
FTQVFTTKEH PLVMFLDDLQ WADSASLKLM QLLMSEREQG YLLLIGAYRD
510 520 530 540 550
NEVFPGHPLM LTLNEVSKVG ATINRITLAS LSRTSLNQLV ADMLKCAEVL
560 570 580 590 600
AQPLAGLVYQ KTQGNPFFAT QFLKTLHQEQ FITFNIQAGH WQCDITQIRK
610 620 630 640 650
AALTDDVVEF MAKQLQKLPD ETQNILKLAA CIGNQFDLNT LAIVSEQLPQ
660 670 680 690 700
QVASDLWKGL QEGLILPISE TYKFFQDNNL NDTNTDGISV TYKFLHDRVQ
710 720 730 740 750
QAAYSLIPQE EKQVVHLTIG RHLLNHTSAE QLEEQIFDIV NQLNIGCTLI
760 770 780 790 800
SDTLEQARLV ELNLRAGRKA IATTAYDTAT YCLKYACNLL PTDSWQTQYD
810 820 830 840 850
LALACYSSAA EAAYLNTDLV QMETLAEIVL QQARSLLDAA KVYEIKIDAY
860 870 880 890 900
TSLGEFSKAL TTGLNFLQSF GIEFPTQPNK QDFADFLRQT RQQLAGRSPD
910 920 930 940 950
ELLNLPVMTS PQYQALLRML VQISGATYLA SPALYPLICF QQVQLSVAHG
960 970 980 990 1000
NIPASSFGYV VYGLILCGVV GDIKTGYEFG QLALQLVDKF NNQEYAAKVL
1010 1020 1030 1040 1050
YITSKFTVHW VKNAATTLQP LQEAYTLGLK VGALTYAGYS GYTYAFHAYF
1060 1070 1080 1090 1100
VGKELTALET ECQAYSIGLA NIEQQAFLGY LHIVHQTVAN LLGKCENPTK
1110 1120 1130 1140 1150
LVGTIFDEGV TLANLEKAND KTGLWHFHLC KVTLTYLFEC HDQTLDHCQQ
1160 1170 1180 1190 1200
AKLNAGGGSG MLNVPILYFY RALACFTQLS AHSQTDELWA LIADAQEKLQ
1210 1220 1230 1240 1250
NWAIYAPMNC QHRYDLICAE EQRVLGHPQQ AIDFYDRAIS LAQENGYIAE
1260 1270 1280 1290 1300
QAIANELTAK FYLGWGKEKI AAVYMQEAYY CYARWGAKAK TNHLEHRYPH
1310 1320 1330 1340 1350
LLRPILQSVS QPLNVWESLT STITPDISLH TSHSSLGNST NINNAIDIAS
1360 1370 1380 1390 1400
MIKASQSLSA TLQLDELLHQ LTHIILQNSG GDRCALICPN SEGEWQVVAI
1410 1420 1430 1440 1450
ATPETTQLCS ELLDGNPNLP VKLIQYVKNT QQIVMIDNLK TDLPVTDEYL
1460 1470 1480 1490 1500
IRQQPKSLLC LPIISHGQLI GIVSLKNRST SGVFTSDRIF LLNFLCTQAA
1510 1520 1530 1540 1550
ISLENARLYQ KAQTYAQKLE QSQLQIVQSE KMASLGNLVA GVAHEINNPI
1560 1570 1580 1590 1600
GFLNGSISNA QEYVQDLLDY IALYQQYHPK AAAPVKTKAK NIDLEYLCED
1610 1620 1630 1640 1650
LPKLLNSMQG ASDRIQSIST SLRTFSRADS EYKVMANLHE GIDSTLLILK
1660 1670 1680 1690 1700
YRLKANEYRP AIPVITEYSE LPAIKCFPGQ LNQVFMNILA NAIDMFDEMA
1710 1720 1730 1740 1750
KSQSYKEIEA HPQKITIRTT MEANQVIISI ADNGKGMSED VKVRIFDHLF
1760 1770 1780 1790
TTKGVGKGTG LGLAIARQIV VEKHGGSLEV QSQLGKGSDF CIQLPLL
Length:1,797
Mass (Da):200,434
Last modified:October 25, 2005 - v1
Checksum:i64D3FE6C4838E3E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA24101.1.
RefSeqiWP_011321172.1. NC_007413.1.
YP_324996.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA24101; ABA24101; Ava_4503.
KEGGiava:Ava_4503.
PATRICi35430445. VBIAnaVar43351_5744.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA24101.1.
RefSeqiWP_011321172.1. NC_007413.1.
YP_324996.1. NC_007413.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240292.Ava_4503.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA24101; ABA24101; Ava_4503.
KEGGiava:Ava_4503.
PATRICi35430445. VBIAnaVar43351_5744.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000263148.
KOiK00903.
OMAiANGASEM.
OrthoDBiEOG6QVRHV.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-4563-MONOMER.

Family and domain databases

Gene3Di1.25.40.10. 2 hits.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 2 hits.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3M4I5_ANAVT
AccessioniPrimary (citable) accession number: Q3M4I5
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: April 1, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.