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Protein
Submitted name:

Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensor

Gene

Ava_4504

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: -Protein predictedi

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseImported, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:G7WH-10133-MONOMER

Names & Taxonomyi

Protein namesi
Submitted name:
Serine/Threonine protein kinase and Signal Transduction Histidine Kinase (STHK) with GAF sensorImported (EC:2.7.11.17Imported)
Gene namesi
Ordered Locus Names:Ava_4504Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeTrichormus
Proteomesi
  • UP000002533 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_4504

Structurei

3D structure databases

ProteinModelPortaliQ3M4I4
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini14 – 279Protein kinaseInterPro annotationAdd BLAST266
Domaini1539 – 1795Histidine kinaseInterPro annotationAdd BLAST257

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1054 – 1074Sequence analysisAdd BLAST21
Coiled coili1510 – 1530Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG4105BZU Bacteria
ENOG410XNMH LUCA
HOGENOMiHOG000263148
OMAiCIESAIQ
OrthoDBiPOG091H0264

Family and domain databases

CDDicd00075 HATPase_c, 1 hit
cd00082 HisKA, 1 hit
Gene3Di3.30.450.40, 1 hit
3.30.565.10, 1 hit
InterProiView protein in InterPro
IPR003018 GAF
IPR029016 GAF-like_dom_sf
IPR003594 HATPase_C
IPR036890 HATPase_C_sf
IPR005467 His_kinase_dom
IPR003661 HisK_dim/P
IPR036097 HisK_dim/P_sf
IPR011009 Kinase-like_dom_sf
IPR027417 P-loop_NTPase
IPR000719 Prot_kinase_dom
IPR008271 Ser/Thr_kinase_AS
IPR004358 Sig_transdc_His_kin-like_C
PfamiView protein in Pfam
PF01590 GAF, 1 hit
PF02518 HATPase_c, 1 hit
PF00512 HisKA, 1 hit
PF00069 Pkinase, 1 hit
PRINTSiPR00344 BCTRLSENSOR
SMARTiView protein in SMART
SM00065 GAF, 1 hit
SM00387 HATPase_c, 1 hit
SM00388 HisKA, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF47384 SSF47384, 2 hits
SSF52540 SSF52540, 1 hit
SSF55874 SSF55874, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50109 HIS_KIN, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q3M4I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSATVDTTVL LSGYQLIEQL YHGSKTLVYR GIRRKESVAQ PVVIKLLQRD
60 70 80 90 100
YPSFSELLQF RNQYTITKNL NIPGVVRPSS LEPYGNSYAL VMEDFGGVSL
110 120 130 140 150
GTYSQTHSLS LVDVLAIAIQ LANILHDLYQ NRVIHKDIKP ANLLIHPDTK
160 170 180 190 200
KIQLIDFSIA SLLPKETEAV KHPKVLEGTL PYLAPEQTGR MNRGIDYRSD
210 220 230 240 250
FYAFGVTLFE MLTGQLPFIS DDPLELVHCH IAKPAPSVCA LRPEIPSVIG
260 270 280 290 300
EIIGKLMAKN AEDRYQSALG LQYDLQNCLE QLQNTGKIEA FEIATRDICD
310 320 330 340 350
RFLIPEKLYG REEEVATLLT AFERVSNGNS ELMLVAGFSG IGKTAVVNEV
360 370 380 390 400
HKPIVEKRGY FIKGKFDQFN RSTPFSAFVQ AFRDLIGQLL SESDEQLQTW
410 420 430 440 450
KTQLLQALGE NGQVIIEVIP ELERIIGEQP PARELSGNAA QNRFKLLFQN
460 470 480 490 500
FIHVFTKPEH PLVIFLDDLQ WADSASLNLM QGLIAESKIG YLLLLGAYRD
510 520 530 540 550
HEVYPAHPLM LTLEAIEKTG ATINTITLQP LSLTSLNQLI TDTLNCTATL
560 570 580 590 600
AQPLTKLVNQ KTQGNPFFAT QFLKALYQDE LIYFDLVTGY WQCDLVQVKA
610 620 630 640 650
AALTDDVVEF MALQLQKLPP VTQDILKLAA CIGNQFDLNT LAIVSEISPA
660 670 680 690 700
ETSTILWKAL QEELILPLSE TYKFFQSSPH QTTGDCQITI SYKFFHDRVQ
710 720 730 740 750
QAAYSLIPQE QKTATHLRIG QLLLTHTPET ELENRIFDIV NQLNVGVAYL
760 770 780 790 800
TDQPEKQRLL ELNLMAGRKA KVATAYVVAV DYLNTAIKLL EEDSWQNQYE
810 820 830 840 850
LTLSLYDLVA ETEYLNTNFP TSELLVREIL VNAKHTLDKI KAYEIQIQAY
860 870 880 890 900
TAQNKLIEAI NIGREVLGLL GIDLPEDGNI ETIITEHGRL KSLFGERLIE
910 920 930 940 950
DLVNLPELTD LQQGAALRIL CGLFAPIYLA KPMLLPLKIF TMVKICIQYG
960 970 980 990 1000
NSPQSAIAYS LYGLFLCASE EIADGYQFGQ LAMTVLDKFN AQELRSKVYL
1010 1020 1030 1040 1050
TFALFIKHWQ DSINSTLNIF LEGLKSGLDT GDLEYVGYCA NCYAQFLFWT
1060 1070 1080 1090 1100
GQNLEIAEAE ANKYCALMQD LKQDVSLIWG NTWRQTVMNL QAKVDNPQML
1110 1120 1130 1140 1150
VGECFDETVT LPALISSRNT NGICYVYLAK LFLAYLLGAD EQAIKYASLF
1160 1170 1180 1190 1200
EEYEQGAAGL LIVPLKNFYQ SLSILSLYPK LDTEQQSRHL EKITNNQQKM
1210 1220 1230 1240 1250
QNWADHAPLN YQHKFYLVAA EKHRVLDEKT AAIELYDQAI ALAKTNGYIQ
1260 1270 1280 1290 1300
EAALANELAA KFYLDWGKEK VAAAYMQEAY YCYAHWGSLA KTNDLESRYP
1310 1320 1330 1340 1350
QLLRPILQQV IHPLSILETF ASLTSSVHST RHQSSSSTSI NHMLDFAALL
1360 1370 1380 1390 1400
QVSQAISSTI QLDKLLQTMT ETVLENSGAD YCALILCQEG EWQVKVIANS
1410 1420 1430 1440 1450
QQTSLQSTPL ENNPTVPVKL IQYVKNTLET VVIHDLKTEI PGVMSNYLDQ
1460 1470 1480 1490 1500
HHPKSVLCLP LVNQGNLSAI LYLENQVTSD VFTSDRLLVL KFLSSQAVIA
1510 1520 1530 1540 1550
LENARLYHQV QKTLEDLQQA QVQIVQSEKM SALGNLVAGV AHEINNPVGC
1560 1570 1580 1590 1600
IVGNIGAAQE YINDLLGVID LYGEKFPQPG TEIEDELQAI DLEYLREDLP
1610 1620 1630 1640 1650
KLIRAMKDGS DRIKAISESL RTFSRADSDQ KQPFNLHDGL ESTLLILRHR
1660 1670 1680 1690 1700
LKANQYRPAI EVITEYGNLP LVKCFPGQLN QVFMNILANA IDALDESNPG
1710 1720 1730 1740 1750
YSFTEIEANP NRIIIRTTVA GEQIKIAISD NGHGIPEEVK AKIFDHLFTT
1760 1770 1780 1790
KGVGKGTGLG LAIAHQIIVE KHGGAIAVNS QPGIGTEFLL TLPIS
Length:1,795
Mass (Da):200,798
Last modified:October 25, 2005 - v1
Checksum:iAAE5361B2DD69205
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA Translation: ABA24102.1

Genome annotation databases

EnsemblBacteriaiABA24102; ABA24102; Ava_4504
KEGGiava:Ava_4504

Similar proteinsi

Entry informationi

Entry nameiQ3M4I4_ANAVT
AccessioniPrimary (citable) accession number: Q3M4I4
Entry historyiIntegrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: March 28, 2018
This is version 101 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
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Main funding by: National Institutes of Health