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Protein

Histidine kinase

Gene

Ava_4504

Organism
Anabaena variabilis (strain ATCC 29413 / PCC 7937)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Keywords - Ligandi

ATP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-4564-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Histidine kinaseSAAS annotation (EC:2.7.13.3SAAS annotation)
Gene namesi
Ordered Locus Names:Ava_4504Imported
OrganismiAnabaena variabilis (strain ATCC 29413 / PCC 7937)Imported
Taxonomic identifieri240292 [NCBI]
Taxonomic lineageiBacteriaCyanobacteriaNostocalesNostocaceaeAnabaena
ProteomesiUP000002533 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Keywords - PTMi

PhosphoproteinSAAS annotation

Interactioni

Protein-protein interaction databases

STRINGi240292.Ava_4504.

Structurei

3D structure databases

ProteinModelPortaliQ3M4I4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains histidine kinase domain.SAAS annotation

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000263148.
OMAiAFSKIEH.
OrthoDBiEOG690M91.

Family and domain databases

Gene3Di1.10.287.130. 2 hits.
1.25.40.10. 2 hits.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3M4I4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSATVDTTVL LSGYQLIEQL YHGSKTLVYR GIRRKESVAQ PVVIKLLQRD
60 70 80 90 100
YPSFSELLQF RNQYTITKNL NIPGVVRPSS LEPYGNSYAL VMEDFGGVSL
110 120 130 140 150
GTYSQTHSLS LVDVLAIAIQ LANILHDLYQ NRVIHKDIKP ANLLIHPDTK
160 170 180 190 200
KIQLIDFSIA SLLPKETEAV KHPKVLEGTL PYLAPEQTGR MNRGIDYRSD
210 220 230 240 250
FYAFGVTLFE MLTGQLPFIS DDPLELVHCH IAKPAPSVCA LRPEIPSVIG
260 270 280 290 300
EIIGKLMAKN AEDRYQSALG LQYDLQNCLE QLQNTGKIEA FEIATRDICD
310 320 330 340 350
RFLIPEKLYG REEEVATLLT AFERVSNGNS ELMLVAGFSG IGKTAVVNEV
360 370 380 390 400
HKPIVEKRGY FIKGKFDQFN RSTPFSAFVQ AFRDLIGQLL SESDEQLQTW
410 420 430 440 450
KTQLLQALGE NGQVIIEVIP ELERIIGEQP PARELSGNAA QNRFKLLFQN
460 470 480 490 500
FIHVFTKPEH PLVIFLDDLQ WADSASLNLM QGLIAESKIG YLLLLGAYRD
510 520 530 540 550
HEVYPAHPLM LTLEAIEKTG ATINTITLQP LSLTSLNQLI TDTLNCTATL
560 570 580 590 600
AQPLTKLVNQ KTQGNPFFAT QFLKALYQDE LIYFDLVTGY WQCDLVQVKA
610 620 630 640 650
AALTDDVVEF MALQLQKLPP VTQDILKLAA CIGNQFDLNT LAIVSEISPA
660 670 680 690 700
ETSTILWKAL QEELILPLSE TYKFFQSSPH QTTGDCQITI SYKFFHDRVQ
710 720 730 740 750
QAAYSLIPQE QKTATHLRIG QLLLTHTPET ELENRIFDIV NQLNVGVAYL
760 770 780 790 800
TDQPEKQRLL ELNLMAGRKA KVATAYVVAV DYLNTAIKLL EEDSWQNQYE
810 820 830 840 850
LTLSLYDLVA ETEYLNTNFP TSELLVREIL VNAKHTLDKI KAYEIQIQAY
860 870 880 890 900
TAQNKLIEAI NIGREVLGLL GIDLPEDGNI ETIITEHGRL KSLFGERLIE
910 920 930 940 950
DLVNLPELTD LQQGAALRIL CGLFAPIYLA KPMLLPLKIF TMVKICIQYG
960 970 980 990 1000
NSPQSAIAYS LYGLFLCASE EIADGYQFGQ LAMTVLDKFN AQELRSKVYL
1010 1020 1030 1040 1050
TFALFIKHWQ DSINSTLNIF LEGLKSGLDT GDLEYVGYCA NCYAQFLFWT
1060 1070 1080 1090 1100
GQNLEIAEAE ANKYCALMQD LKQDVSLIWG NTWRQTVMNL QAKVDNPQML
1110 1120 1130 1140 1150
VGECFDETVT LPALISSRNT NGICYVYLAK LFLAYLLGAD EQAIKYASLF
1160 1170 1180 1190 1200
EEYEQGAAGL LIVPLKNFYQ SLSILSLYPK LDTEQQSRHL EKITNNQQKM
1210 1220 1230 1240 1250
QNWADHAPLN YQHKFYLVAA EKHRVLDEKT AAIELYDQAI ALAKTNGYIQ
1260 1270 1280 1290 1300
EAALANELAA KFYLDWGKEK VAAAYMQEAY YCYAHWGSLA KTNDLESRYP
1310 1320 1330 1340 1350
QLLRPILQQV IHPLSILETF ASLTSSVHST RHQSSSSTSI NHMLDFAALL
1360 1370 1380 1390 1400
QVSQAISSTI QLDKLLQTMT ETVLENSGAD YCALILCQEG EWQVKVIANS
1410 1420 1430 1440 1450
QQTSLQSTPL ENNPTVPVKL IQYVKNTLET VVIHDLKTEI PGVMSNYLDQ
1460 1470 1480 1490 1500
HHPKSVLCLP LVNQGNLSAI LYLENQVTSD VFTSDRLLVL KFLSSQAVIA
1510 1520 1530 1540 1550
LENARLYHQV QKTLEDLQQA QVQIVQSEKM SALGNLVAGV AHEINNPVGC
1560 1570 1580 1590 1600
IVGNIGAAQE YINDLLGVID LYGEKFPQPG TEIEDELQAI DLEYLREDLP
1610 1620 1630 1640 1650
KLIRAMKDGS DRIKAISESL RTFSRADSDQ KQPFNLHDGL ESTLLILRHR
1660 1670 1680 1690 1700
LKANQYRPAI EVITEYGNLP LVKCFPGQLN QVFMNILANA IDALDESNPG
1710 1720 1730 1740 1750
YSFTEIEANP NRIIIRTTVA GEQIKIAISD NGHGIPEEVK AKIFDHLFTT
1760 1770 1780 1790
KGVGKGTGLG LAIAHQIIVE KHGGAIAVNS QPGIGTEFLL TLPIS
Length:1,795
Mass (Da):200,798
Last modified:October 25, 2005 - v1
Checksum:iAAE5361B2DD69205
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA24102.1.
RefSeqiWP_011321173.1. NC_007413.1.
YP_324997.1. NC_007413.1.

Genome annotation databases

EnsemblBacteriaiABA24102; ABA24102; Ava_4504.
KEGGiava:Ava_4504.
PATRICi35430447. VBIAnaVar43351_5745.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000117 Genomic DNA. Translation: ABA24102.1.
RefSeqiWP_011321173.1. NC_007413.1.
YP_324997.1. NC_007413.1.

3D structure databases

ProteinModelPortaliQ3M4I4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi240292.Ava_4504.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABA24102; ABA24102; Ava_4504.
KEGGiava:Ava_4504.
PATRICi35430447. VBIAnaVar43351_5745.

Phylogenomic databases

eggNOGiCOG0515.
HOGENOMiHOG000263148.
OMAiAFSKIEH.
OrthoDBiEOG690M91.

Enzyme and pathway databases

BioCyciAVAR240292:GCY3-4564-MONOMER.

Family and domain databases

Gene3Di1.10.287.130. 2 hits.
1.25.40.10. 2 hits.
3.30.450.40. 1 hit.
3.30.565.10. 1 hit.
3.40.50.300. 1 hit.
InterProiIPR003661. EnvZ-like_dim/P.
IPR003018. GAF.
IPR029016. GAF_dom_like.
IPR003594. HATPase_C.
IPR011009. Kinase-like_dom.
IPR027417. P-loop_NTPase.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR004358. Sig_transdc_His_kin-like_C.
IPR005467. Sig_transdc_His_kinase_core.
IPR009082. Sig_transdc_His_kinase_dimeric.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF01590. GAF. 1 hit.
PF02518. HATPase_c. 1 hit.
PF00512. HisKA. 1 hit.
PF00069. Pkinase. 1 hit.
[Graphical view]
PRINTSiPR00344. BCTRLSENSOR.
SMARTiSM00065. GAF. 1 hit.
SM00387. HATPase_c. 1 hit.
SM00388. HisKA. 1 hit.
[Graphical view]
SUPFAMiSSF47384. SSF47384. 2 hits.
SSF52540. SSF52540. 1 hit.
SSF55781. SSF55781. 1 hit.
SSF55874. SSF55874. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50109. HIS_KIN. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequence of Anabaena variabilis ATCC 29413."
    Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 29413 / PCC 7937Imported.

Entry informationi

Entry nameiQ3M4I4_ANAVT
AccessioniPrimary (citable) accession number: Q3M4I4
Entry historyi
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: June 24, 2015
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.