Serine/threonine protein kinase with Chase2 sensor

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

• ATP binding Source: InterPro
• protein serine/threonine kinase activity Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsⁱ

Enzyme and pathway databases

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationⁱ

Topology

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Cellular componentⁱ

• integral component of membrane Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componentⁱ

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Domains and Repeats

Coiled coil

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domainⁱ

Phylogenomic databases

Family and domain databases

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MIIGISNKLR AAFIKDKSYR DTAVNKNWWQ IILVTSLGVT ALVWGVRELK 
        60         70         80         90        100
WLQSWELKAY DQMLRSRPAE PPDSRILLVT VTEEDLAKKG WNLADDTINR 
       110        120        130        140        150
LLTKLASYQP RVIALNLYRP EQTNLGAGLE NPTNIISACL SSSMGRSEVP 
       160        170        180        190        200
PPPNFPPENI GYNDVISDIE EDQVVRRALV FSEANDSKCA TQFSIAALAA 
       210        220        230        240        250
ITYLEQTGIH VDFEKHQFHL GKTAFPILTP NSGSYKGVDA KGYQILLNYR 
       260        270        280        290        300
HPNHLAPTFT LTEVLNNQVN PNLVKDRLVI IGTTASSIHP GLYTPYSAAK 
       310        320        330        340        350
GQPTRTPSVF IHTQIASQLL STVLDGRPLI WYWPDWAELV WLWAWSLVGS 
       360        370        380        390        400
ILAWRLKHPL LVVVVLGIAL TGLVIICAGL FLDAGWIPLI PPALTLVMSG 
       410        420        430        440        450
VSVIIYRTYR TQQQTKVIML QVEKQQEVIE QLNILLNEAT AIADTTAFYD 
       460        470        480        490        500
QHSHHDSVVV TPRKKADDLL LGGRYSISSV LGAGGFGRTY LAQDTQRPGN 
       510        520        530        540        550
PTCVVKKLMP ARKDTKFLQV ARRLFITEAE ILESLGQHQQ IPALLAYFEV 
       560        570        580        590        600
NEEFYLVEQY IAGHTLYEEL PPVTGLQSEA FVIEMLKGVL EVLAFVHEHR 
       610        620        630        640        650
VIHRDVKPTN IIRSAEDNRL VLIDFGAVKL MQPPTDQKTE LATVAIGTRG 
       660        670        680        690        700
YAPPEQFAGH PRLASDIYAV GMMGIQALTG ILPQELPPDP ETGNVMWRSH 
       710        720        730        740 
ATVSEELALI LDKMVRYHFS DRYQSAATVL QDLNRLSSLI QTSSIS     

Sequence databases

Genome annotation databases

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ

• 100% Identity
• 90% Identity
• 50% Identity

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ