ID   GLPK_ANAVT              Reviewed;         500 AA.
AC   Q3M3M2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2005, sequence version 1.
DT   16-JUN-2009, entry version 31.
DE   RecName: Full=Glycerol kinase;
DE            EC=2.7.1.30;
DE   AltName: Full=ATP:glycerol 3-phosphotransferase;
DE   AltName: Full=Glycerokinase;
DE            Short=GK;
GN   Name=glpK; OrderedLocusNames=Ava_4817;
OS   Anabaena variabilis (strain ATCC 29413 / PCC 7937).
OC   Bacteria; Cyanobacteria; Nostocales; Nostocaceae; Anabaena.
OX   NCBI_TaxID=240292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.;
RT   "Complete sequence of Anabaena variabilis ATCC 29413.";
RL   Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Key enzyme in the regulation of glycerol uptake and
CC       metabolism (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + glycerol = ADP + sn-glycerol 3-
CC       phosphate.
CC   -!- PATHWAY: Polyol metabolism; glycerol degradation via glycerol
CC       kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.
CC   -!- SIMILARITY: Belongs to the FGGY kinase family.
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DR   EMBL; CP000117; ABA24414.1; -; Genomic_DNA.
DR   RefSeq; YP_325309.1; -.
DR   GeneID; 3679393; -.
DR   GenomeReviews; CP000117_GR; Ava_4817.
DR   KEGG; ava:Ava_4817; -.
DR   NMPDR; fig|240292.3.peg.3672; -.
DR   HOGENOM; Q3M3M2; -.
DR   OMA; Q3M3M2; SRCIIFD.
DR   BioCyc; AVAR240292:AVA_4817-MON; -.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004370; F:glycerol kinase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR   GO; GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00186; -; 1.
DR   InterPro; IPR000577; Carb_kinase_FGGY.
DR   InterPro; IPR018485; Carb_kinase_FGGY_C.
DR   InterPro; IPR018483; Carb_kinase_FGGY_CS.
DR   InterPro; IPR018484; Carb_kinase_FGGY_N.
DR   InterPro; IPR005999; Glycerol_kin.
DR   PANTHER; PTHR10196; FGGY_kin; 1.
DR   PANTHER; PTHR10196:SF9; Glycerol_kin; 1.
DR   Pfam; PF02782; FGGY_C; 1.
DR   Pfam; PF00370; FGGY_N; 1.
DR   TIGRFAMs; TIGR01311; glycerol_kin; 1.
DR   PROSITE; PS00933; FGGY_KINASES_1; FALSE_NEG.
DR   PROSITE; PS00445; FGGY_KINASES_2; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Complete proteome; Glycerol metabolism; Kinase;
KW   Nucleotide-binding; Transferase.
FT   CHAIN         1    500       Glycerol kinase.
FT                                /FTId=PRO_1000077408.
FT   NP_BIND     414    418       ATP (By similarity).
FT   BINDING      16     16       Substrate (By similarity).
FT   BINDING      20     20       ATP (By similarity).
FT   BINDING      86     86       Substrate (By similarity).
FT   BINDING     138    138       Substrate (By similarity).
FT   BINDING     243    243       Substrate (By similarity).
FT   BINDING     265    265       ATP (By similarity).
FT   BINDING     313    313       ATP; via carbonyl oxygen (By similarity).
SQ   SEQUENCE   500 AA;  55073 MW;  6F636D675FE8F34F CRC64;
     MQTSSSGYIL ALDLGTTGNR AFIFNNAGKI VAQAYKELTQ HYPQPGWLEH DAEEIWQDTC
     WVMKTAIANA QISPSEIAAI GLTVQRETCL LWDKTTGKPL HKAIVWQDRR TAPLCHQLQE
     KGYAQEIYSR TGLVVDAYFS ATKLRWLLDY ITGVDLKNVL AGTIDTWILW KLTGGKVHAT
     DHSNASRTML MNLKTGEWDE QLLEILQIPA HILPQIQPSL GKFGLTDTSL LDTAIPITAI
     LGDQQAALFG HGCDRPGLMK CTYGTGSFLV AHTGSNIVRS QHQLISTIAW TQYNSQENIN
     IGYALEGSMF TSGACIQWLR DGIKLIKTAA ETETMANQVD DNGGVYFVPA FSGLGAPYWD
     MNARGAFFGI TASVQPQHLV RAVLEAIAYQ VLEVVQAINA SCSSPMQRLI VDGGACENNF
     LMQFQADVLG IPVERPTMRD TTVQGAAFAA GLAVGFWDSY TALVNQRQID RIFEPGEGSQ
     NAIYNFATWQ KAVKRSLDWV
//