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Q3M381 (Q3M381_ANAVT) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Magnesium-protoporphyrin IX monomethyl ester [oxidative] cyclase 2 HAMAP MF_01840
Short name=Mg-protoporphyrin IX monomethyl ester oxidative cyclase 2 HAMAP MF_01840
EC=1.14.13.81 HAMAP MF_01840
Gene names
Name:acsF2 HAMAP MF_01840
Ordered Locus Names:Ava_4958
OrganismAnabaena variabilis (strain ATCC 29413 / PCC 7937) [Complete proteome] [HAMAP]
Taxonomic identifier240292 [NCBI]
Taxonomic lineageBacteria › Cyanobacteria › Nostocales › Nostocaceae › Anabaena

Protein attributes

Sequence length358 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) By similarity. HAMAP MF_01840

Catalytic activity

131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + 2 H2O. HAMAP MF_01840

131-oxo-magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = divinylprotochlorophyllide + NADP+ + 2 H2O. HAMAP MF_01840

Magnesium-protoporphyrin IX 13-monomethyl ester + NADPH + O2 = 131-hydroxy-magnesium-protoporphyrin IX 13-monomethyl ester + NADP+ + H2O. HAMAP MF_01840

Cofactor

Iron By similarity. HAMAP MF_01840

Pathway

Porphyrin biosynthesis; chlorophyll biosynthesis (light-independent). HAMAP MF_01840

Sequence similarities

Belongs to the AcsF family. HAMAP MF_01840

Sequences

Sequence LengthMass (Da)Tools
Q3M381 [UniParc].

Last modified October 25, 2005. Version 1.
Checksum: D521F0EE095DC365

FASTA35842,270
        10         20         30         40         50         60 
MVDSLKKPGF EEIRPGVKVP AKETLLTPRF YTTDFDEMAR MDISVNEDEL LAILEEFRTD 

        70         80         90        100        110        120 
YNRHHFVRDA EFEKSWDHID GDTRRLFVEF LERSCTAEFS GFLLYKELGR RLKDKSPVLA 

       130        140        150        160        170        180 
ECFNLMSRDE ARHAGFLNKA MSDFNLSLDL GFLTKSRNYT FFKPKFIFYA TYLSEKIGYW 

       190        200        210        220        230        240 
RYITIYRHLE AHPEDRIYPI FRFFENWCQD ENRHGDFFDA IMKSQPQMLN DWKAKLWSRF 

       250        260        270        280        290        300 
FLLSVFATMY LNDIQRKDFY ASIGLDARDY DIYVIKKTNE TAGRVFPVIL DVDSPEFYER 

       310        320        330        340        350 
LDICVENSEK LSAIASSNTP KFLQFFQKLP VLASTGWQLL RLYLMKPIDA VSAQGAAR

« Hide

References

[1]"Complete sequence of Anabaena variabilis ATCC 29413."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyrpides N., Mavrommatis K., Richardson P.
Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 29413 / PCC 7937.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000117 Genomic DNA. Translation: ABA24555.1.
RefSeqYP_325450.1. NC_007413.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ3M381.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3679067.
GenomeReviewsGene locus Ava_4958 in contig CP000117_GR.
KEGGava:Ava_4958.
NMPDRfig|240292.3.peg.3753.
PATRIC35431455. VBIAnaVar43351_6246.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGNOG10633.
HOGENOMHBG284843.
OMAHGDFFDA.
PhylomeDBQ3M381.
ProtClustDBPRK13654.

Family and domain databases

HAMAPMF_01840. AcsF.
[Tree]
InterProIPR008434. AcsF.
IPR009078. Ferritin/RR-like.
IPR003251. Rubrerythrin.
[Graphical view]
KOK04035.
PfamPF02915. Rubrerythrin. 1 hit.
[Graphical view]
SUPFAMSSF47240. Ferritin/RR_like. 1 hit.
TIGRFAMsTIGR02029. AcsF. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3M381_ANAVT
AccessionPrimary (citable) accession number: Q3M381
Entry history
Integrated into UniProtKB/TrEMBL: October 25, 2005
Last sequence update: October 25, 2005
Last modified: December 14, 2011
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info