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Protein
Submitted name:

PTCH protein-10

Gene

PTCH

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Submitted name:
PTCH protein-10Imported
Gene namesi
Name:PTCHImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei159 – 184HelicalSequence analysisAdd BLAST26
Transmembranei205 – 228HelicalSequence analysisAdd BLAST24
Transmembranei234 – 257HelicalSequence analysisAdd BLAST24

GO - Cellular componenti

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PeptideAtlasiQ3LFT4.

Expressioni

Gene expression databases

BgeeiENSG00000185920.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini153 – 259SSD (sterol-sensing)InterPro annotationAdd BLAST107

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

InterProiView protein in InterPro
IPR000731. SSD.
PfamiView protein in Pfam
PF12349. Sterol-sensing. 1 hit.
PROSITEiView protein in PROSITE
PS50156. SSD. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q3LFT4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
GHGYMDRPCL NPADPDCPAT APNKNSTKPL DMALVLNGGC HGLSRKYMHW
60 70 80 90 100
QEELIVGGTV KNSTGKLVSA HALQTMFQLM TPKQMYEHFK GYEYVSHINW
110 120 130 140 150
NEDKAAAILE AWQRTYVEVV HQSVAQNSTQ KVLSFTTTTL DDILKSFSDV
160 170 180 190 200
SVIRVASGYL LMVLPFLALG VGVDDVFLLA HAFSETGQNK RIPFEDRTGE
210 220 230 240 250
CLKRTGASVA LTSISNVTAF FMAALIPIPA LRAFSLQAAV VVVFNFAMVL
260 270 280 290 300
LIFPAILSMD LYRREDRRLD IFCCFTSPCV SRVIQVEPQA YTDTHDNTRY
310 320 330 340
SPPPPYSSHS FAHETQITMQ STVQLRTEYD PHTHVYYTTA EPRSEISV
Length:348
Mass (Da):38,882
Last modified:November 8, 2005 - v1
Checksum:i04E06AEC9AAAE642
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei348Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB233422 mRNA. Translation: BAE45302.1.
UniGeneiHs.494538.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB233422 mRNA. Translation: BAE45302.1.
UniGeneiHs.494538.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PeptideAtlasiQ3LFT4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Gene expression databases

BgeeiENSG00000185920.

Family and domain databases

InterProiView protein in InterPro
IPR000731. SSD.
PfamiView protein in Pfam
PF12349. Sterol-sensing. 1 hit.
PROSITEiView protein in PROSITE
PS50156. SSD. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ3LFT4_HUMAN
AccessioniPrimary (citable) accession number: Q3LFT4
Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: March 15, 2017
This is version 48 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.