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Protein

Protein Wnt

Gene

WNT5b

Organism
Gallus gallus (Chicken)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

  • lens fiber cell development Source: BHF-UCL
  • Wnt signaling pathway Source: UniProtKB-KW

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:WNT5bImported
OrganismiGallus gallus (Chicken)Imported
Taxonomic identifieri9031 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiArchelosauriaArchosauriaDinosauriaSaurischiaTheropodaCoelurosauriaAvesNeognathaeGalloanseraeGalliformesPhasianidaePhasianinaeGallus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 23Sequence analysisAdd BLAST23
ChainiPRO_500422766824 – 359Protein WntSequence analysisAdd BLAST336

Keywords - PTMi

Disulfide bondSAAS annotation

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
HOGENOMiHOG000039529
HOVERGENiHBG001595
KOiK00444
PhylomeDBiQ3L255

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR026537 Wnt5b
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 1 hit
PTHR12027:SF87 PTHR12027:SF87, 1 hit
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit

Sequencei

Sequence statusi: Complete.

Q3L255-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTGPRLALAA ALLCSCTSPV ADANSWWSLA MNPIQRPEMY IIGAQPVCSQ
60 70 80 90 100
LPGLSPGQRK LCQLYQEHMV FIGEGARSAI KECQYQFRQR RWNCSTVDNT
110 120 130 140 150
SVFGRVMKIG SRETAFTYAV SAAGVVNAIS RACREGELSS CGCSRTARPK
160 170 180 190 200
DLPRDWLWGG CGDNVEYGYR FAKEFVDAKE REKNYVRGSE EQARMLMNLQ
210 220 230 240 250
NNEAGRRAVY KLADVACKCH GVSGSCSLKT CWLQLADFRK VGDLLKEKYD
260 270 280 290 300
SAAAMRISRK GKLELVNNRF NMPTQEDLVY VDPSPDYCLR NETTGSLGTQ
310 320 330 340 350
GRLCNKTSEG MDGCELMCCG RGYDQFKSVQ VERCHCKFHW CCYVKCKKCT

EIVDQYVCK
Length:359
Mass (Da):40,314
Last modified:November 8, 2005 - v1
Checksum:i776C3171389D01BF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY753289 mRNA Translation: AAW81991.1
RefSeqiNP_001032346.1, NM_001037269.1
UniGeneiGga.7960

Genome annotation databases

GeneIDi418154
KEGGigga:418154

Similar proteinsi

Entry informationi

Entry nameiQ3L255_CHICK
AccessioniPrimary (citable) accession number: Q3L255
Entry historyiIntegrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: February 28, 2018
This is version 89 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health