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Protein

Portal protein

Gene

BBRF1

Organism
Epstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Forms a portal in the viral capsid through which viral DNA is translocated during DNA packaging. Assembles as a dodecamer at a single fivefold axe of the T=16 icosahedric capsid. Binds to the molecular motor that translocates the viral DNA, termed terminase.UniRule annotation

GO - Biological processi

Keywordsi

Biological processViral genome packaging, Viral release from host cell

Names & Taxonomyi

Protein namesi
Recommended name:
Portal proteinUniRule annotation
Gene namesi
ORF Names:BBRF1
OrganismiEpstein-Barr virus (strain GD1) (HHV-4) (Human herpesvirus 4)
Taxonomic identifieri10376 [NCBI]
Taxonomic lineageiVirusesdsDNA viruses, no RNA stageHerpesviralesHerpesviridaeGammaherpesvirinaeLymphocryptovirus
Virus hostiHomo sapiens (Human) [TaxID: 9606]
Proteomesi
  • UP000007641 Componenti: Genome

Subcellular locationi

Q3KSR9:
  • Virion UniRule annotation
  • Host nucleus UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Host nucleus, Virion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003759731 – 613Portal proteinAdd BLAST613

Interactioni

Subunit structurei

Homododecamerizes. Interacts with terminase subunits TRM1 and TRM3.UniRule annotation

Binary interactionsi

WithEntry#Exp.IntActNotes
BSRF1P0CK492EBI-2621338,EBI-2621334From Epstein-Barr virus (strain B95-8).

Protein-protein interaction databases

IntActiQ3KSR9. 2 interactors.

Structurei

3D structure databases

SMRiQ3KSR9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the herpesviridae portal protein family.UniRule annotation

Phylogenomic databases

OrthoDBiVOG0900002I.

Family and domain databases

HAMAPiMF_04012. HSV_PORTL. 1 hit.
InterProiView protein in InterPro
IPR002660. Herpes_Portal.
PfamiView protein in Pfam
PF01763. Herpes_UL6. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3KSR9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFNMNVDESA SGALGSSAIP VHPTPASVRL FEILQGKYAY VQGQTIYANL
60 70 80 90 100
RNPGVFSRQV FTHLFKRAIS HCTYDDVLHD WNKFEACIQK RWPSDDSCAS
110 120 130 140 150
RFRESTFESW STTMKLTVRD LLTTNIYRVL HSRSVLSYER YVDWICATGM
160 170 180 190 200
VPAVKKPITQ ELHSKIKSLR DRCVCRELGH ERTIRSIGTE LYEATREIIE
210 220 230 240 250
SLNSTFIPQF TEVTIEYLPR SDEYVAYYCG RRIRLHVLFP PAIFAGTVTF
260 270 280 290 300
DSPVQRLYQN IFMCYRTLEH AKICQLLNTA PLKAIVGHGG RDMYKDILAH
310 320 330 340 350
LEQNSQRKDP KKELLNLLVK LSENKTISGV TDVVEEFITD ASNNLVDRNR
360 370 380 390 400
LFGQPGETAA QGLKKKVSNT VVKCLTDQIN EQFDQINGLE KERELYLKKI
410 420 430 440 450
RSMESQLQAS LGPGGNNPAA SAPAAVAAEA ASVDILTGST ASAIEKLFNS
460 470 480 490 500
PSASLGARVS GHNESILNSF VSQYIPPSRE MTKDLTELWE SELFNTFKLT
510 520 530 540 550
PVVDNQGQRL YVRYSSDTIS ILLGPFTYLV AELSPVELVT DVYATLGIVE
560 570 580 590 600
IIDELYRSSR LAIYIEDLGR KYCPASATGG DHGIRQAPSA RGDAEPDHAK
610
SKPARDPPPG AGS
Length:613
Mass (Da):68,455
Last modified:November 8, 2005 - v1
Checksum:i064B83A4F8FFDB72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY961628 Genomic DNA. Translation: AAY41130.1.

Similar proteinsi

Entry informationi

Entry nameiPORTL_EBVG
AccessioniPrimary (citable) accession number: Q3KSR9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 26, 2009
Last sequence update: November 8, 2005
Last modified: October 25, 2017
This is version 45 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families