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Q3KSM3

- RDRP_PRV

UniProt

Q3KSM3 - RDRP_PRV

Protein

RNA-directed RNA polymerase

Gene
N/A
Organism
Pieris rapae virus
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 30 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    RNA-dependent RNA polymerase which replicates the viral genome composed of 2 RNA segments, RNA1 AND RNA2.Curated

    Catalytic activityi

    Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).PROSITE-ProRule annotation

    GO - Molecular functioni

    1. RNA binding Source: InterPro
    2. RNA-directed RNA polymerase activity Source: UniProtKB-KW

    GO - Biological processi

    1. transcription, DNA-templated Source: InterPro
    2. viral RNA genome replication Source: InterPro

    Keywords - Molecular functioni

    Nucleotidyltransferase, RNA-directed RNA polymerase, Transferase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    RNA-directed RNA polymerase (EC:2.7.7.48)
    Short name:
    RdRp
    Alternative name(s):
    RNA replicase
    OrganismiPieris rapae virus
    Taxonomic identifieri327392 [NCBI]
    Taxonomic lineageiVirusesssRNA positive-strand viruses, no DNA stageNodaviridaeunclassified Nodaviridae
    Virus hostiPieris rapae (Small white butterfly) (Artogeia rapae) [TaxID: 64459]

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 10141014RNA-directed RNA polymerasePRO_0000223688Add
    BLAST

    Proteomic databases

    PRIDEiQ3KSM3.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3KSM3.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini618 – 740123RdRp catalyticPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the nodaviridae RNA polymerase family.Curated
    Contains 1 RdRp catalytic domain.PROSITE-ProRule annotation

    Family and domain databases

    InterProiIPR001205. RNA-dir_pol_C.
    IPR007094. RNA-dir_pol_PSvirus.
    [Graphical view]
    PfamiPF00680. RdRP_1. 1 hit.
    [Graphical view]
    PROSITEiPS50507. RDRP_SSRNA_POS. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3KSM3-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSSVIKTIVV KTLQCTVKCV CVGVRQQYGL LRRHPKTIAC ALVGGIIAHD     50
    VLHLYAAVYR VENPWEFVPT EGPRGVIVLR VYNALRFTAA KWRWNCWTIF 100
    GKFPFNSEQF SRIMETSTER KPDLRPLLVP AHETIEVYPC NNIHSHPRSA 150
    EFRSSANEYL VRSVRRAGYP PYVVSSSKRD FCDGNRFFYC PKDFGMQFRN 200
    DPISNNHALV FTDVDYYANM NRWLQLFLPT CLYTLVPTRL NYSNDEFAYR 250
    FENNEIVYNV TGGGEYRHSL WDYKGDTVTV VDEYGNLLIF DIEQRRVQGD 300
    EQHRLIWLLP KAKITDPLWI VGPTEWYDKL LVRKTVQQGR LKILWEPIAD 350
    DLSIGLHGSN YSVSLKGELF EAIRTRISCK DSTPYVSDVE RMLREAKHKN 400
    FLTDAPILYH CFQDDVIIRP NVVKTGSFPV TYNAIPKKAP SVTEDPKMPG 450
    QVVTTPLVSQ PALFAGKGFN ADKACIEGRI EKVRNVTKFP IKYVRYAAEF 500
    VKLVIPETIA GTGVPNSIGM IREEQDKVAQ RARFDRVAPI MSTQTENSIK 550
    AFIKTEMYAA AKAPRNISTM APEITIQSSA YSLPMAKIFK KIPWYCPGKN 600
    PKEITLRLAE VCLQDPDHEL EEGDYTCMDG TQSPDYSDLL LLPIYMRYFA 650
    KQYRGQFKNL YNQIYKQRAT TSSGVPYNPE MTIRSGSSIT THAGTLNNAF 700
    NIYAALRDMG YDETTAWDKV GAVFGDDSLN ANHQGEFHSY IEHVTKVLGM 750
    RYKSNLRERG QPVLFLGRYF VDPITSYDSF ADPMRTIGKL HATANKNVSV 800
    EQGAANKAHG YITTDSKTPI IGAWARRVLE ITKKKFKNGT GEEQYRCSNA 850
    WPQKDEAAIR AAMAAVLEVD EAQLIAQNEA VLKVNSLDQF PVVFDTYYDH 900
    KQLAEVDGQL VGTDLHIKEE DERQPETSID SVPSTGPPPS NGDPNAGGKP 950
    TDGPSKGKRK VKGRRPRTAG DPATLRLTDA GSSRRVKPPR KLRPEAKRGG 1000
    RPIETLVFKN SSLS 1014
    Length:1,014
    Mass (Da):114,607
    Last modified:November 8, 2005 - v1
    Checksum:i0691D5F6E57F3D12
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY962576 Genomic RNA. Translation: AAY27743.1.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY962576 Genomic RNA. Translation: AAY27743.1 .

    3D structure databases

    ProteinModelPortali Q3KSM3.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q3KSM3.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR001205. RNA-dir_pol_C.
    IPR007094. RNA-dir_pol_PSvirus.
    [Graphical view ]
    Pfami PF00680. RdRP_1. 1 hit.
    [Graphical view ]
    PROSITEi PS50507. RDRP_SSRNA_POS. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence of the non-structural protein gene encoded by RNA1 of a new alpha noda-like virus isolated from Pieris rapae larvae in China."
      Liu C., Zhang J., Yi F., Wang J., Wang X., Hu Y.
      Submitted (MAR-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

    Entry informationi

    Entry nameiRDRP_PRV
    AccessioniPrimary (citable) accession number: Q3KSM3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2006
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 30 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3