ID   PPAT_XENLA              Reviewed;         420 AA.
AC   Q3KQG9; Q52KY6;
DT   31-OCT-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   16-JUN-2009, entry version 20.
DE   RecName: Full=Testicular acid phosphatase homolog;
DE            EC=3.1.3.2;
DE   Flags: Precursor;
GN   Name=acpt;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Amphibia; Batrachia; Anura; Mesobatrachia; Pipoidea; Pipidae;
OC   Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo, and Kidney;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: A phosphate monoester + H(2)O = an alcohol +
CC       phosphate.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane
CC       protein (Potential).
CC   -!- SIMILARITY: Belongs to the histidine acid phosphatase family.
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DR   EMBL; BC094140; AAH94140.1; -; mRNA.
DR   EMBL; BC106212; AAI06213.1; -; mRNA.
DR   RefSeq; NP_001087080.1; -.
DR   UniGene; Xl.48988; -.
DR   GeneID; 446918; -.
DR   KEGG; xla:446918; -.
DR   Xenbase; XB-FEAT-960830; acpp.
DR   HOVERGEN; Q3KQG9; -.
DR   BRENDA; 3.1.3.2; 648.
DR   GO; GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
DR   GO; GO:0003993; F:acid phosphatase activity; IEA:EC.
DR   InterPro; IPR000560; Histidine_acid_Pase.
DR   Pfam; PF00328; Acid_phosphat_A; 1.
DR   PROSITE; PS00616; HIS_ACID_PHOSPHAT_1; 1.
DR   PROSITE; PS00778; HIS_ACID_PHOSPHAT_2; 1.
PE   2: Evidence at transcript level;
KW   Disulfide bond; Glycoprotein; Hydrolase; Membrane; Signal;
KW   Transmembrane.
FT   SIGNAL        1     24       Potential.
FT   CHAIN        25    420       Testicular acid phosphatase homolog.
FT                                /FTId=PRO_0000259644.
FT   TOPO_DOM     25    385       Extracellular (Potential).
FT   TRANSMEM    386    406       Potential.
FT   TOPO_DOM    407    420       Cytoplasmic (Potential).
FT   ACT_SITE     39     39       Nucleophile (By similarity).
FT   ACT_SITE    286    286       Proton donor (By similarity).
FT   CARBOHYD     29     29       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    122    122       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    188    188       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    216    216       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    266    266       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    272    272       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    330    330       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    352    352       N-linked (GlcNAc...) (Potential).
FT   CARBOHYD    383    383       N-linked (GlcNAc...) (Potential).
FT   DISULFID    156    369       By similarity.
FT   DISULFID    211    309       By similarity.
FT   DISULFID    344    348       By similarity.
FT   CONFLICT    171    171       E -> D (in Ref. 1; AAH94140).
SQ   SEQUENCE   420 AA;  48860 MW;  F9EA0D73B4470B0F CRC64;
     MKRAVVILWL PLAFTNLYIL TTFCQRTDNL TFVVAVFRHG DRAPIDTYPN DPHKEKLWPN
     GLQQLTQEGM RQQYELGRFL RRRYDHFLSS TYNRQEIYVR STDYDRTLMS AQASLAGLYP
     PNGSQLWHRD IHWQPIPVHT VPASQDRLLK FPSKDCPRYY ELMRETIQQP EYQDKVNSWK
     DFMERIANYT GYRAETTISR WVWKVYDTLF CQKSHNISLP SWATADVVKT LKEISAFDVK
     THVEMHKTNE KARLTGGILV DALLRNFSDV VNKSLPLKML MYSAHDSTLI ALQGALKVYN
     GLHPPYSSCH IIEFYKEADG THSVRMFYRN ETVREPYELA LPGCDSPCPL LNFTQLMAPV
     ISMDWKKDCA SDGSLQYRIG SENNTVLALS ICVGILGLTL TVMLFCLWRT YKLPVRRYQR
//