SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q3KQG9

- PPAT_XENLA

UniProt

Q3KQG9 - PPAT_XENLA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Testicular acid phosphatase homolog
Gene
acpt
Organism
Xenopus laevis (African clawed frog)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Catalytic activityi

A phosphate monoester + H2O = an alcohol + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei39 – 391Nucleophile By similarity
Active sitei286 – 2861Proton donor By similarity

GO - Molecular functioni

  1. acid phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Testicular acid phosphatase homolog (EC:3.1.3.2)
Gene namesi
Name:acpt
OrganismiXenopus laevis (African clawed frog)
Taxonomic identifieri8355 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusXenopus

Organism-specific databases

XenbaseiXB-GENE-960834. acpp.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini25 – 385361Extracellular Reviewed prediction
Add
BLAST
Transmembranei386 – 40621Helical; Reviewed prediction
Add
BLAST
Topological domaini407 – 42014Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2424 Reviewed prediction
Add
BLAST
Chaini25 – 420396Testicular acid phosphatase homolog
PRO_0000259644Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Glycosylationi29 – 291N-linked (GlcNAc...) Reviewed prediction
Glycosylationi122 – 1221N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi156 ↔ 369 By similarity
Glycosylationi188 – 1881N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi211 ↔ 309 By similarity
Glycosylationi216 – 2161N-linked (GlcNAc...) Reviewed prediction
Glycosylationi266 – 2661N-linked (GlcNAc...) Reviewed prediction
Glycosylationi272 – 2721N-linked (GlcNAc...) Reviewed prediction
Glycosylationi330 – 3301N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi344 ↔ 348 By similarity
Glycosylationi352 – 3521N-linked (GlcNAc...) Reviewed prediction
Glycosylationi383 – 3831N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Interactioni

Subunit structurei

Homodimer By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ3KQG9.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

HOVERGENiHBG002203.
KOiK14410.

Family and domain databases

Gene3Di3.40.50.1240. 1 hit.
InterProiIPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view]
PfamiPF00328. His_Phos_2. 1 hit.
[Graphical view]
SUPFAMiSSF53254. SSF53254. 1 hit.
PROSITEiPS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q3KQG9-1 [UniParc]FASTAAdd to Basket

« Hide

MKRAVVILWL PLAFTNLYIL TTFCQRTDNL TFVVAVFRHG DRAPIDTYPN    50
DPHKEKLWPN GLQQLTQEGM RQQYELGRFL RRRYDHFLSS TYNRQEIYVR 100
STDYDRTLMS AQASLAGLYP PNGSQLWHRD IHWQPIPVHT VPASQDRLLK 150
FPSKDCPRYY ELMRETIQQP EYQDKVNSWK DFMERIANYT GYRAETTISR 200
WVWKVYDTLF CQKSHNISLP SWATADVVKT LKEISAFDVK THVEMHKTNE 250
KARLTGGILV DALLRNFSDV VNKSLPLKML MYSAHDSTLI ALQGALKVYN 300
GLHPPYSSCH IIEFYKEADG THSVRMFYRN ETVREPYELA LPGCDSPCPL 350
LNFTQLMAPV ISMDWKKDCA SDGSLQYRIG SENNTVLALS ICVGILGLTL 400
TVMLFCLWRT YKLPVRRYQR 420
Length:420
Mass (Da):48,860
Last modified:November 8, 2005 - v1
Checksum:iF9EA0D73B4470B0F
GO

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti171 – 1711E → D in AAH94140. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC094140 mRNA. Translation: AAH94140.1.
BC106212 mRNA. Translation: AAI06213.1.
RefSeqiNP_001087080.1. NM_001093611.1.
UniGeneiXl.48988.

Genome annotation databases

GeneIDi446918.
KEGGixla:446918.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BC094140 mRNA. Translation: AAH94140.1 .
BC106212 mRNA. Translation: AAI06213.1 .
RefSeqi NP_001087080.1. NM_001093611.1.
UniGenei Xl.48988.

3D structure databases

ProteinModelPortali Q3KQG9.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 446918.
KEGGi xla:446918.

Organism-specific databases

CTDi 55.
Xenbasei XB-GENE-960834. acpp.

Phylogenomic databases

HOVERGENi HBG002203.
KOi K14410.

Family and domain databases

Gene3Di 3.40.50.1240. 1 hit.
InterProi IPR000560. His_Pase_superF_clade-2.
IPR029033. His_PPase_superfam.
[Graphical view ]
Pfami PF00328. His_Phos_2. 1 hit.
[Graphical view ]
SUPFAMi SSF53254. SSF53254. 1 hit.
PROSITEi PS00616. HIS_ACID_PHOSPHAT_1. 1 hit.
PS00778. HIS_ACID_PHOSPHAT_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. NIH - Xenopus Gene Collection (XGC) project
    Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Embryo and Kidney.

Entry informationi

Entry nameiPPAT_XENLA
AccessioniPrimary (citable) accession number: Q3KQG9
Secondary accession number(s): Q52KY6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 8, 2005
Last modified: June 11, 2014
This is version 38 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi