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Protein

Uncharacterized protein C11orf85

Gene

C11orf85

Organism
Homo sapiens (Human)
Status
Reviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized protein C11orf85
Gene namesi
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640 Componenti: Chromosome 11

Organism-specific databases

HGNCiHGNC:27441. C11orf85.

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA162377786.

Polymorphism and mutation databases

BioMutaiC11orf85.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 216216Uncharacterized protein C11orf85PRO_0000325832Add
BLAST

Proteomic databases

PaxDbiQ3KP22.
PRIDEiQ3KP22.

PTM databases

PhosphoSiteiQ3KP22.

Expressioni

Gene expression databases

BgeeiQ3KP22.
CleanExiHS_C11orf85.
ExpressionAtlasiQ3KP22. baseline and differential.
GenevestigatoriQ3KP22.

Organism-specific databases

HPAiHPA039921.

Structurei

3D structure databases

ProteinModelPortaliQ3KP22.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

eggNOGiNOG29491.
GeneTreeiENSGT00390000007971.
HOGENOMiHOG000037935.
HOVERGENiHBG101163.
InParanoidiQ3KP22.
OMAiATEHFVV.
PhylomeDBiQ3KP22.
TreeFamiTF336863.

Family and domain databases

InterProiIPR027816. DUF4544.
[Graphical view]
PfamiPF15077. DUF4544. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q3KP22-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MSLKPFTYPF PETRFLHAGP NVYKFKIRYG KSIRGEEIEN KEVITQELED
60 70 80 90 100
SVRVVLGNLD NLQPFATEHF IVFPYKSKWE RVSHLKFKHG EIILIPYPFV
110 120 130 140 150
FTLYVEMKWF HENLSPGKPI SDSPLGLVPV EKKAVGAVMR KRKHMDEPSS
160 170 180 190 200
PSRPGLDRIG KEKPNKDCRR LWPLISLMSR NKILSGDTAC QGELSHPCST
210
THLHLRSEQP PASLGF
Length:216
Mass (Da):24,809
Last modified:November 8, 2005 - v1
Checksum:i293D4D14024BED42
GO
Isoform 2 (identifier: Q3KP22-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-106: Missing.
     159-216: IGKEKPNKDC...SEQPPASLGF → AKIGTSSQGP...RYFFRKSSHS

Note: No experimental confirmation available.

Show »
Length:148
Mass (Da):16,599
Checksum:i5EAA2F438C4FC312
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 106106Missing in isoform 2. 1 PublicationVSP_056890Add
BLAST
Alternative sequencei159 – 21658IGKEK…ASLGF → AKIGTSSQGPSKKKPPVETR RNRERKTQQGLQETLASDIT DVQKQDSEWGHSLPGRIVPP LQHNSPPPKERAATGFFGFL SSLFPFRYFFRKSSHS in isoform 2. 1 PublicationVSP_056891Add
BLAST

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093130 mRNA. Translation: BAG52661.1.
AP000436 Genomic DNA. No translation available.
AP001187 Genomic DNA. No translation available.
BC106951 mRNA. Translation: AAI06952.1.
BC106952 mRNA. Translation: AAI06953.1.
CCDSiCCDS31603.1. [Q3KP22-1]
RefSeqiNP_001032302.1. NM_001037225.2. [Q3KP22-1]
XP_006718569.1. XM_006718506.2. [Q3KP22-2]
UniGeneiHs.567793.

Genome annotation databases

EnsembliENST00000301896; ENSP00000301896; ENSG00000168070. [Q3KP22-1]
ENST00000432175; ENSP00000395273; ENSG00000168070. [Q3KP22-1]
GeneIDi283129.
KEGGihsa:283129.
UCSCiuc001ocb.1. human. [Q3KP22-1]

Polymorphism and mutation databases

BioMutaiC11orf85.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK093130 mRNA. Translation: BAG52661.1.
AP000436 Genomic DNA. No translation available.
AP001187 Genomic DNA. No translation available.
BC106951 mRNA. Translation: AAI06952.1.
BC106952 mRNA. Translation: AAI06953.1.
CCDSiCCDS31603.1. [Q3KP22-1]
RefSeqiNP_001032302.1. NM_001037225.2. [Q3KP22-1]
XP_006718569.1. XM_006718506.2. [Q3KP22-2]
UniGeneiHs.567793.

3D structure databases

ProteinModelPortaliQ3KP22.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ3KP22.

Polymorphism and mutation databases

BioMutaiC11orf85.

Proteomic databases

PaxDbiQ3KP22.
PRIDEiQ3KP22.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000301896; ENSP00000301896; ENSG00000168070. [Q3KP22-1]
ENST00000432175; ENSP00000395273; ENSG00000168070. [Q3KP22-1]
GeneIDi283129.
KEGGihsa:283129.
UCSCiuc001ocb.1. human. [Q3KP22-1]

Organism-specific databases

CTDi283129.
GeneCardsiGC11M064705.
HGNCiHGNC:27441. C11orf85.
HPAiHPA039921.
neXtProtiNX_Q3KP22.
PharmGKBiPA162377786.
GenAtlasiSearch...

Phylogenomic databases

eggNOGiNOG29491.
GeneTreeiENSGT00390000007971.
HOGENOMiHOG000037935.
HOVERGENiHBG101163.
InParanoidiQ3KP22.
OMAiATEHFVV.
PhylomeDBiQ3KP22.
TreeFamiTF336863.

Miscellaneous databases

GenomeRNAii283129.
NextBioi35469672.
PROiQ3KP22.

Gene expression databases

BgeeiQ3KP22.
CleanExiHS_C11orf85.
ExpressionAtlasiQ3KP22. baseline and differential.
GenevestigatoriQ3KP22.

Family and domain databases

InterProiIPR027816. DUF4544.
[Graphical view]
PfamiPF15077. DUF4544. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete sequencing and characterization of 21,243 full-length human cDNAs."
    Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R., Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H., Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.
    , Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K., Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H., Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M., Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K., Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T., Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M., Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S., Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H., Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K., Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N., Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S., Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O., Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H., Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B., Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y., Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K., Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T., Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T., Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y., Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H., Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y., Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H., Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O., Isogai T., Sugano S.
    Nat. Genet. 36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Tissue: Testis.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).

Entry informationi

Entry nameiCK085_HUMAN
AccessioniPrimary (citable) accession number: Q3KP22
Secondary accession number(s): B3KS99
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: November 8, 2005
Last modified: April 29, 2015
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.