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Q3KM87 (Q3KM87_CHLTA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Chromosomal replication initiator protein DnaA 2 HAMAP MF_00377
Gene names
Name:dnaA_2 EMBL AAX50535.1
Synonyms:dnaA2 HAMAP MF_00377
Ordered Locus Names:CTA_0297
OrganismChlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]
Taxonomic identifier315277 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length455 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids By similarity. HAMAP MF_00377 RuleBase RU000577

Subcellular location

Cytoplasm By similarity HAMAP MF_00377.

Sequence similarities

Belongs to the DnaA family. HAMAP MF_00377 RuleBase RU004227

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Nucleotide binding154 – 1618ATP By similarity HAMAP MF_00377

Sequences

Sequence LengthMass (Da)Tools
Q3KM87 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: F593F8FBB50A91F1

FASTA45551,330
        10         20         30         40         50         60 
MLTCNDCSTW EQFVNYIKTR CSKTAFENWI APIQVLEESS EKIRLEIPNI FVQSYLLDNY 

        70         80         90        100        110        120 
KKDLCSFVPL DAEGNPALEF VVAEIKRSSP LVTPSIAKPA TEVSEENKDF QLKLNGAYRF 

       130        140        150        160        170        180 
DNFIEGPSNQ FVKSAALGIA ARPGRSYNPL FIHGGVGLGK THLLHAVGHY VREHHKNLRI 

       190        200        210        220        230        240 
HCITTEAFIN DLVHHLRVKS IDKMKNFYRS LDLLLVDDIQ FLQNRQNFEE EFCNTFETLI 

       250        260        270        280        290        300 
HLSKQIVVTS DKPPGQLKLS ERIIARMEWG LVAHVGVPDL ETRVAILQHK AEQKGLNIPN 

       310        320        330        340        350        360 
EIAFYIADHV YGNVRQLEGA INKLTAYCLL FNKPLTETTV RDTLKELFRA PSKQKVSVES 

       370        380        390        400        410        420 
ILKSVATVFQ VKIQDLKGSS RAKNVPLARQ VAMYLAKTLI TDSLVAIGAA FGKTHSTVLY 

       430        440        450 
ACKTIEQKIE KDALLKNQIS LCKNNIAIDS PQHFV

« Hide

References

[1]"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains."
Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.
Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000051 Genomic DNA. Translation: AAX50535.1.
RefSeqYP_328083.1. NC_007429.1.

3D structure databases

ProteinModelPortalQ3KM87.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3KM87.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3687327.
GenomeReviewsGene locus CTA_0297 in contig CP000051_GR.
KEGGcta:CTA_0297.
PATRIC32022472. VBIChlTra31516_0306.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0593.
HOGENOMHBG695666.
OMACHTLNAL.
PhylomeDBQ3KM87.
ProtClustDBPRK00149.

Family and domain databases

HAMAPMF_00377. DnaA_bact.
[Tree]
InterProIPR003593. ATPase_AAA+_core.
IPR001957. Chromosome_initiator_DnaA.
IPR020591. Chromosome_initiator_DnaA-like.
IPR018312. Chromosome_initiator_DnaA_CS.
IPR013159. DnaA_C.
IPR013317. DnaA_Hda.
IPR010921. Trp_repressor/repl_initiator.
[Graphical view]
Gene3DG3DSA:1.10.1750.10. DnaA_C. 1 hit.
KOK02313.
PfamPF00308. Bac_DnaA. 1 hit.
PF08299. Bac_DnaA_C. 1 hit.
[Graphical view]
PRINTSPR00051. DNAA.
SMARTSM00382. AAA. 1 hit.
SM00760. Bac_DnaA_C. 1 hit.
[Graphical view]
SUPFAMSSF48295. Trp_repress_rep. 1 hit.
TIGRFAMsTIGR00362. DnaA. 1 hit.
PROSITEPS01008. DNAA. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ3KM87_CHLTA
AccessionPrimary (citable) accession number: Q3KM87
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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