Reviewed, UniProtKB/Swiss-Prot Q3KM33 (TRPF_CHLTA)

Names and origin

Protein names

Recommended name:
    N-(5'-phosphoribosyl)anthranilate isomerase
      Short name=PRAI
    EC=5.3.1.24

Gene names

Name:	trpF
Ordered Locus Names:	CTA_0354

Organism

Chlamydia trachomatis (strain A/HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]

Taxonomic identifier

315277 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	208 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate. HAMAP MF_00135
Pathway	Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5. HAMAP MF_00135
Sequence similarities	Belongs to the trpF family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Aromatic amino acid biosynthesis Tryptophan biosynthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	tryptophan biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	phosphoribosylanthranilate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 208	208	N-(5'-phosphoribosyl)anthranilate isomerase HAMAP MF_00135		PRO_1000018589

Sequences

	Sequence		Length	Mass (Da)
	Q3KM33-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: F0CB86A3B4C40D04	FASTA	208	22,775
	10 20 30 40 50 60 MKVKICGITH PDDAREAAKA GADYIGMIFA KDSRRCVSEE KAKYIVEAIQ EGNSEPVGVF 70 80 90 100 110 120 PEHSVEEILA ITETTGITSI QLSGEDILFK FSHLREHFSI FYVVSVYSNG QPSAALPPMN 130 140 150 160 170 180 DAVTVVYDHI GGERGSPFDW KAFSPFQHNN WMLGGGVNLW NIKEGISLLN PRGIDVSSGV 190 200 ECPGILRKDI FLMQALINSA KELSSSTL

References

[1]	"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains." Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D. Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000051 Genomic DNA. Translation: AAX50589.1.
RefSeq	YP_328137.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3687983.
GenomeReviews	Gene locus CTA_0354 in contig CP000051_GR.
KEGG	cta:CTA_0354.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3KM33.
OMA	Q3KM33. ETTGITS.
Enzyme and pathway databases
BioCyc	CTRA315277-1:CTA_0354-MON.
Family and domain databases
HAMAP	MF_00135. [Tree]
InterPro	IPR013785. Aldolase_TIM. IPR001240. PRAI. [Graphical view]
Gene3D	G3DSA:3.20.20.70. Aldolase_TIM. 1 hit.
Pfam	PF00697. PRAI. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

TRPF_CHLTA

Accession

Primary (citable) accession number: Q3KM33

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 8, 2005
Last modified:	June 16, 2009
This is version 24 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)