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Q3KLX6

- G6PI_CHLTA

UniProt

Q3KLX6 - G6PI_CHLTA

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Protein

Glucose-6-phosphate isomerase

Gene

pgi

Organism
Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

D-glucose 6-phosphate = D-fructose 6-phosphate.UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei346 – 3461Proton donorUniRule annotation
Active sitei377 – 3771UniRule annotation
Active sitei492 – 4921UniRule annotation

GO - Molecular functioni

  1. glucose-6-phosphate isomerase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. gluconeogenesis Source: UniProtKB-HAMAP
  2. glycolytic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Gluconeogenesis, Glycolysis

Enzyme and pathway databases

BioCyciCTRA315277:GI4C-412-MONOMER.
UniPathwayiUPA00109; UER00181.
UPA00138.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-6-phosphate isomeraseUniRule annotation (EC:5.3.1.9UniRule annotation)
Short name:
GPIUniRule annotation
Alternative name(s):
Phosphoglucose isomeraseUniRule annotation
Short name:
PGIUniRule annotation
Phosphohexose isomeraseUniRule annotation
Short name:
PHIUniRule annotation
Gene namesi
Name:pgiUniRule annotation
Ordered Locus Names:CTA_0412
OrganismiChlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B)
Taxonomic identifieri315277 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydia
ProteomesiUP000002532: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 524524Glucose-6-phosphate isomerasePRO_0000230916Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi315277.CTA_0412.

Structurei

3D structure databases

ProteinModelPortaliQ3KLX6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GPI family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0166.
HOGENOMiHOG000261370.
KOiK01810.
OMAiISIYESN.
OrthoDBiEOG64R61J.

Family and domain databases

Gene3Di1.10.1390.10. 1 hit.
HAMAPiMF_00473. G6P_isomerase.
InterProiIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERiPTHR11469. PTHR11469. 1 hit.
PfamiPF00342. PGI. 1 hit.
[Graphical view]
PRINTSiPR00662. G6PISOMERASE.
PROSITEiPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3KLX6-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGKGFLDCES LVALQEMALH PIDLTASGCL SEERIQKNSL SAEGFTYSYA
60 70 80 90 100
TERVDDRCLE ALQGLTEERE LIKQMECMQQ GAIMNRIEGF QSESRPVLHT
110 120 130 140 150
ATRAWVRDQD LHEEAAAIAR HSKEEALRLA EFLYIARAKF STLVQMGIGG
160 170 180 190 200
SELGPKAMYF AMQGSCPSDK RIFFVSNIDP DNAAEVLREI DLEQTLVVVV
210 220 230 240 250
SKSGTTLEPA ANEELFRQAY QNKGLSIAKH FVAVTSQGSP MDDKSRYLEV
260 270 280 290 300
FHLWDSIGGR FSATSMVGGV VLGFAFGYEA FIEFLQGAAA IDAHALTPKM
310 320 330 340 350
RENLPLLSAM LGVWNRNLLG YPTTAVIPYS TGLKYFTAHL QQCGMESNGK
360 370 380 390 400
SISREGKEIS FRTSPIIWGD VGTNCQHSFF QSLHQGTDIV PVEFIGFLHN
410 420 430 440 450
QRGLDCVLSG SSSSQKLFAN LVAQSLALAQ GRDNANSNKR FKGNRPSSIL
460 470 480 490 500
VAQQLSPRIA GSLLAFYEHK FAFQGFCWGI NSFDQEGVSL GKELATQIIG
510 520
IMSGNAPVEF PEARGMLRLF NVLT
Length:524
Mass (Da):57,649
Last modified:April 4, 2006 - v2
Checksum:i4245A7E42A2735C5
GO

Sequence cautioni

The sequence AAX50646.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000051 Genomic DNA. Translation: AAX50646.1. Different initiation.
RefSeqiWP_011324712.1. NC_007429.1.
YP_328194.1. NC_007429.1.

Genome annotation databases

EnsemblBacteriaiAAX50646; AAX50646; CTA_0412.
GeneIDi3688040.
KEGGicta:CTA_0412.
PATRICi32022706. VBIChlTra31516_0419.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000051 Genomic DNA. Translation: AAX50646.1 . Different initiation.
RefSeqi WP_011324712.1. NC_007429.1.
YP_328194.1. NC_007429.1.

3D structure databases

ProteinModelPortali Q3KLX6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 315277.CTA_0412.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAX50646 ; AAX50646 ; CTA_0412 .
GeneIDi 3688040.
KEGGi cta:CTA_0412.
PATRICi 32022706. VBIChlTra31516_0419.

Phylogenomic databases

eggNOGi COG0166.
HOGENOMi HOG000261370.
KOi K01810.
OMAi ISIYESN.
OrthoDBi EOG64R61J.

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00181 .
UPA00138 .
BioCyci CTRA315277:GI4C-412-MONOMER.

Family and domain databases

Gene3Di 1.10.1390.10. 1 hit.
HAMAPi MF_00473. G6P_isomerase.
InterProi IPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view ]
PANTHERi PTHR11469. PTHR11469. 1 hit.
Pfami PF00342. PGI. 1 hit.
[Graphical view ]
PRINTSi PR00662. G6PISOMERASE.
PROSITEi PS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains."
    Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.
    Infect. Immun. 73:6407-6418(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: HAR-13 / ATCC VR-571B.

Entry informationi

Entry nameiG6PI_CHLTA
AccessioniPrimary (citable) accession number: Q3KLX6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 4, 2006
Last sequence update: April 4, 2006
Last modified: October 29, 2014
This is version 59 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3