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Q3KLS0 (DAPF_CHLTA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Diaminopimelate epimerase
Short name=DAP epimerase
EC=5.1.1.7
Gene names
Name:dapF
Ordered Locus Names:CTA_0470
OrganismChlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]
Taxonomic identifier315277 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length275 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197

Pathway

Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1. HAMAP MF_00197

Subcellular location

Cytoplasm By similarity HAMAP MF_00197.

Sequence similarities

Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
   Biological processAmino-acid biosynthesis
Lysine biosynthesis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processlysine biosynthetic process via diaminopimelate

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functiondiaminopimelate epimerase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 275275Diaminopimelate epimerase HAMAP MF_00197
PRO_1000011867

Sites

Active site721 By similarity
Active site2071 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3KLS0 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 38883BBB99436F45

FASTA27530,546
        10         20         30         40         50         60 
MGFSSLLTTC RYLLYSGAGN SFILGESMPS LEDVLFLCQE EMVDGFLCVE SSEIADAKLT 

        70         80         90        100        110        120 
VFNSDGSIAS MCGNGLRCAM AHVAQCFGLE DVSIETERGV YQGKFFSMNR VLVDMTLPDW 

       130        140        150        160        170        180 
KKAERKLTHV LPGMPEQVFF IDAGVPHVVV FVSDLSKVPV QEWGSFLRYH EDFAPEGVNV 

       190        200        210        220        230        240 
DFVQRKKDDL LLVYTYERGC ERETLSCGTG MLASALVAAD IFSLGQDFSI AVCSRSRNLI 

       250        260        270 
KIFSEKGKVF LEGPVSLLNR SENFGWLEPK SRRFG

« Hide

References

[1]"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains."
Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.
Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HAR-13 / ATCC VR-571B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000051 Genomic DNA. Translation: AAX50702.1.
RefSeqYP_328250.1. NC_007429.1.

3D structure databases

HSSPHSSP built from PDB template 2GKE based on UniProtKB P44859.
ProteinModelPortalQ3KLS0.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3KLS0.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3687343.
GenomeReviewsGene locus CTA_0470 in contig CP000051_GR.
KEGGcta:CTA_0470.
PATRIC32022830. VBIChlTra31516_0479.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0253.
HOGENOMHBG399442.
OMANCASVIA.
PhylomeDBQ3KLS0.
ProtClustDBPRK00450.

Family and domain databases

HAMAPMF_00197. DAP_epimerase.
[Tree]
InterProIPR018510. DAP_epimerase_AS.
IPR001653. DAP_epimerase_DapF.
[Graphical view]
KOK01778.
PfamPF01678. DAP_epimerase. 2 hits.
[Graphical view]
TIGRFAMsTIGR00652. DapF. 1 hit.
PROSITEPS01326. DAP_EPIMERASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameDAPF_CHLTA
AccessionPrimary (citable) accession number: Q3KLS0
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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