Reviewed, UniProtKB/Swiss-Prot Q3KLS0 (DAPF_CHLTA)

Names and origin

Protein names

Recommended name:
    Diaminopimelate epimerase
      Short name=DAP epimerase
    EC=5.1.1.7

Gene names

Name:	dapF
Ordered Locus Names:	CTA_0470

Organism

Chlamydia trachomatis (strain A/HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]

Taxonomic identifier

315277 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia

Protein attributes

Sequence length	275 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	LL-2,6-diaminoheptanedioate = meso-diaminoheptanedioate. HAMAP MF_00197
Pathway	Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-diaminopimelate from LL-diaminopimelate: step 1/1. HAMAP MF_00197
Subcellular location	Cytoplasm By similarity.
Sequence similarities	Belongs to the diaminopimelate epimerase family.

Ontologies

Keywords
Biological process	Amino-acid biosynthesis Lysine biosynthesis
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	lysine biosynthetic process via diaminopimelate Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	diaminopimelate epimerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 275	275	Diaminopimelate epimerase HAMAP MF_00197		PRO_1000011867
Sites
	Active site	72	1	By similarity
	Active site	207	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3KLS0-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 38883BBB99436F45	FASTA	275	30,546
	10 20 30 40 50 60 MGFSSLLTTC RYLLYSGAGN SFILGESMPS LEDVLFLCQE EMVDGFLCVE SSEIADAKLT 70 80 90 100 110 120 VFNSDGSIAS MCGNGLRCAM AHVAQCFGLE DVSIETERGV YQGKFFSMNR VLVDMTLPDW 130 140 150 160 170 180 KKAERKLTHV LPGMPEQVFF IDAGVPHVVV FVSDLSKVPV QEWGSFLRYH EDFAPEGVNV 190 200 210 220 230 240 DFVQRKKDDL LLVYTYERGC ERETLSCGTG MLASALVAAD IFSLGQDFSI AVCSRSRNLI 250 260 270 KIFSEKGKVF LEGPVSLLNR SENFGWLEPK SRRFG

References

[1]	"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains." Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D. Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000051 Genomic DNA. Translation: AAX50702.1.
RefSeq	YP_328250.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3687343.
GenomeReviews	Gene locus CTA_0470 in contig CP000051_GR.
KEGG	cta:CTA_0470.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3KLS0.
OMA	Q3KLS0. NIAFIEN.
Enzyme and pathway databases
BioCyc	CTRA315277-1:CTA_0470-MON.
Family and domain databases
HAMAP	MF_00197. [Tree]
InterPro	IPR001653. DAP_epimerase. IPR018510. DAP_epimerase_CS. [Graphical view]
Pfam	PF01678. DAP_epimerase. 2 hits. [Graphical view]
TIGRFAMs	TIGR00652. DapF. 1 hit.
PROSITE	PS01326. DAP_EPIMERASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

DAPF_CHLTA

Accession

Primary (citable) accession number: Q3KLS0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 8, 2005
Last modified:	June 16, 2009
This is version 23 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)