ID   COAE_CHLTA              Reviewed;         202 AA.
AC   Q3KLK5;
DT   27-JUN-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   16-JUN-2009, entry version 26.
DE   RecName: Full=Dephospho-CoA kinase;
DE            EC=2.7.1.24;
DE   AltName: Full=Dephosphocoenzyme A kinase;
GN   Name=coaE; OrderedLocusNames=CTA_0539;
OS   Chlamydia trachomatis (strain A/HAR-13 / ATCC VR-571B).
OC   Bacteria; Chlamydiae; Chlamydiales; Chlamydiaceae; Chlamydia.
OX   NCBI_TaxID=315277;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=16177312; DOI=10.1128/IAI.73.10.6407-6418.2005;
RA   Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.;
RT   "Comparative genomic analysis of Chlamydia trachomatis oculotropic and
RT   genitotropic strains.";
RL   Infect. Immun. 73:6407-6418(2005).
CC   -!- FUNCTION: Catalyzes the phosphorylation of the 3'-hydroxyl group
CC       of dephosphocoenzyme A to form coenzyme A (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = ADP + CoA.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 5/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the coaE family.
CC   -!- SIMILARITY: Contains 1 DPCK (dephospho-CoA kinase) domain.
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DR   EMBL; CP000051; AAX50767.1; -; Genomic_DNA.
DR   RefSeq; YP_328315.1; -.
DR   GeneID; 3687271; -.
DR   GenomeReviews; CP000051_GR; CTA_0539.
DR   KEGG; cta:CTA_0539; -.
DR   HOGENOM; Q3KLK5; -.
DR   OMA; Q3KLK5; RIIEEQY.
DR   BioCyc; CTRA315277-1:CTA_0539-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00376; -; 1.
DR   InterPro; IPR001977; Depp_CoAkinase.
DR   PANTHER; PTHR10695; Depp_CoAkinase; 1.
DR   Pfam; PF01121; CoaE; 1.
DR   ProDom; PD003329; Depp_CoAkinase; 1.
DR   TIGRFAMs; TIGR00152; Depp_CoAkinase; 1.
DR   PROSITE; PS51219; DPCK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    202       Dephospho-CoA kinase.
FT                                /FTId=PRO_0000243273.
FT   DOMAIN        6    202       DPCK.
FT   NP_BIND      11     18       ATP (Potential).
SQ   SEQUENCE   202 AA;  22900 MW;  762AE4D03D9C3935 CRC64;
     MLDLLKISVT GDPSSGKTEA CQVFEDLGAY VISADKVSHS FLVPYTSVGQ RIIDLLGPEI
     IIENTLSRKA IAEKVFGNRD LLLSLEEILH PEVCRFVEEK YAHVVQEQKY PLFIAEFPLL
     YEIQYADWFD QVILISADTG IRKERFLKKT GGSDTSFDLR CARFSSLEEK ILRADVVIEN
     NGTKEEFRCK VKQCFKALKG TI
//