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Reviewed, UniProtKB/Swiss-Prot Q3KL90 (NTPA_CHLTA)

Last modified July 22, 2008. Version 17. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Nucleoside-triphosphatase
    EC=3.6.1.15
Alternative name(s):
    Nucleoside triphosphate phosphohydrolase
      Short name=NTPase
Gene names
Ordered Locus Names: CTA_0658
OrganismChlamydia trachomatis (strain A/HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]
Taxonomic identifier315277 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia

Protein attributes

Sequence length209 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Function

Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions By similarity.

Catalytic activity

NTP + H(2)O = NDP + phosphate.

Cofactor

Divalent cations By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the HAM1 NTPase family.

Ontologies

Keywords

   Molecular functionHydrolase
   Technical termComplete proteome

Gene Ontology (GO)

   Molecular functionnucleoside-triphosphatase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 209209Nucleoside-triphosphatase
PRO_1000068417

Sequences

Sequence LengthMass (Da)Tools
Q3KL90-1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 63C1B9D2F02758F5

FASTA20923,315
        10         20         30         40         50         60 
MKILIASSHG YKVRETKVFL KKLGEFDIFS LVDYPSYHPP KETGETPEEN AIQKGLFAAQ 

        70         80         90        100        110        120 
TFRCWTIADD SMLIIPALGG LPGKLSASFA GEQANDKDHR KKLLENMRLL ENTIDRSAYF 

       130        140        150        160        170        180 
ECCVALISPF GKIFKAHASC EGTIAFEERG SSGFGYDPLF VKHDYKQTYA ELPEAIKNQV 

       190        200 
SHRAKALVKL QPYVETVLAN HLLAGKESL 

« Hide

References

[1]"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains."
Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.
Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

CP000051 Genomic DNA. Translation: AAX50882.1.
RefSeqYP_328430.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3687502.
GenomeReviewsGene locus CTA_0658 in contig CP000051_GR.
KEGGcta:CTA_0658.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ3KL90.

Enzyme and pathway databases

BioCycCTRA315277-1:CTA_0658-MON.

Family and domain databases

HAMAPMF_01405.
[Tree]
InterProIPR002637. Ham1p_like.
[Graphical view]
PANTHERPTHR11067. Ham1p_like. 1 hit.
PfamPF01725. Ham1p_like. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameNTPA_CHLTA
AccessionPrimary (citable) accession number: Q3KL90
Entry history
Integrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 8, 2005
Last modified: July 22, 2008
This is version 17 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents