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Q3KKZ5 (PSD_CHLTA) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 36. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Ordered Locus Names:CTA_0760
OrganismChlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]
Taxonomic identifier315277 [NCBI]
Taxonomic lineageBacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length301 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00663

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00663

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00663

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 2 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphospholipid biosynthetic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionphosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 259259Phosphatidylserine decarboxylase beta chain By similarity
PRO_1000026606
Chain260 – 30142Phosphatidylserine decarboxylase alpha chain By similarity
PRO_1000026607

Sites

Site259 – 2602Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue2601Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3KKZ5 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: D82A7E0272CCC896

FASTA30134,076
        10         20         30         40         50         60 
MAAREMLYVN RETGKVEQER IICSSLVKFF IETRIGRALY SVLCKNSLFS RIVGWCQRLR 

        70         80         90        100        110        120 
VTRYFIKPFV TKYRICIEES ASPLHDYASF NDFFVRKLKP DARPICQGED ICVTPADGAY 

       130        140        150        160        170        180 
LVFPSMADLS LFTIKNKPFS LESFLGDPQL AHQYAQGSMA IARLAPFDYH RFHFPIAGIA 

       190        200        210        220        230        240 
EAPRRINGHL FSIHPLMLKR NFEVFTENKR EITIITSKEF GEVAYVEVGA LNVGSIHQTF 

       250        260        270        280        290        300 
SPGSYVKKGA EKGFFAFGGS TVVLLFQPQR IIFDADLVGY SAQGLETRCR MGQSLGKRFS 


S

« Hide

References

[1]"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains."
Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D.
Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: HAR-13 / ATCC VR-571B.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000051 Genomic DNA. Translation: AAX50977.1.
RefSeqYP_328525.1. NC_007429.1.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRINGQ3KKZ5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3687890.
GenomeReviewsGene locus CTA_0760 in contig CP000051_GR.
KEGGcta:CTA_0760.
PATRIC32023454. VBIChlTra31516_0777.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0688.
HOGENOMHBG302256.
OMANKREWSI.
PhylomeDBQ3KKZ5.
ProtClustDBPRK00723.

Family and domain databases

HAMAPMF_00663. PS_decarb_type2.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR005221. PS_decarb.
[Graphical view]
KOK01613.
PANTHERPTHR10067. PS_decarb. 1 hit.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00163. PS_decarb. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_CHLTA
AccessionPrimary (citable) accession number: Q3KKZ5
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 36 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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