Q3KKM5 (GLMM_CHLTA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	CTA_0888

Organism

Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]

Taxonomic identifier

315277 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	UDP-N-acetylglucosamine biosynthetic process Inferred from Biological aspect of Ancestor. Source: RefGenome glucose 1-phosphate metabolic process Inferred from Biological aspect of Ancestor. Source: RefGenome
Cellular component	cytosol Inferred from Biological aspect of Ancestor. Source: RefGenome
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucomutase activity Inferred from Biological aspect of Ancestor. Source: RefGenome phosphoglucosamine mutase activity Inferred from Biological aspect of Ancestor. Source: RefGenome
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 458	458	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000301298
Sites
	Active site	106	1	Phosphoserine intermediate By similarity
	Metal binding	106	1	Magnesium; via phosphate group By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
	Metal binding	251	1	Magnesium By similarity
Amino acid modifications
	Modified residue	106	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3KKM5 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: FAF0321FB523B149	FASTA	458	49,377
	10 20 30 40 50 60 MTRDVRQLFG TDGVRGRANF EPMTVETSVL LGKAVAGVLL EKHAGKHRVV VGKDTRLSGY 70 80 90 100 110 120 MFENALIAGL TSMGIETLML GPIPTPGVAF ITRAYRADAG IMISASHNPY RDNGIKIFSS 130 140 150 160 170 180 DGFKIGQAVE ERIEAMVASK DFGKLPDDHA VGKNKRVKDA TGRYIEYAKA TFPKGRTLKG 190 200 210 220 230 240 LRIVLDCAHG ATYRVAPSVF EELDAEVICY GCEPSGCNIN AGCGALWPST IQKAVIEHKA 250 260 270 280 290 300 DVGIALDGDG DRLIMVDEKG HIVDGDMLLS ICASDLKRRQ ALSDNRVVAT VMTNFGVLRY 310 320 330 340 350 360 LESLGIQVTI SPVGDRHVLQ HMLENQAVLG GEQSGHMIFL DYNTTGDGIV SALQVLRIMI 370 380 390 400 410 420 ESESTLSDLT ACIAKSPQAL INVPVTKKVP LESLANVQGV LKEVKEVLGD SGRILLRYSG 430 440 450 TENICRVMVE GTKKHQVDSL AKTIVDVVEA EIGAEISE

References

[1]

"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains." Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D. Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HAR-13 / ATCC VR-571B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000051 Genomic DNA. Translation: AAX51097.1.
RefSeq	YP_328645.1. NC_007429.1.
3D structure databases
HSSP	HSSP built from PDB template 2DKD based on UniProtKB Q9P4V2.
ProteinModelPortal	Q3KKM5.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3KKM5.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3688052.
GenomeReviews	Gene locus CTA_0888 in contig CP000051_GR.
KEGG	cta:CTA_0888.
PATRIC	32023728. VBIChlTra31516_0906.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1109.
HOGENOM	HBG644964.
OMA	IGSAKRI.
PhylomeDB	Q3KKM5.
ProtClustDB	PRK14314.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CHLTA

Accession

Primary (citable) accession number: Q3KKM5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	November 8, 2005
Last modified:	January 25, 2012
This is version 48 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program