Q3KKH0 (GLGB_CHLTA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
1,4-alpha-glucan branching enzyme GlgB
EC=2.4.1.18

Alternative name(s):
1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase
Alpha-(1->4)-glucan branching enzyme
Glycogen branching enzyme
Short name=BE

Gene names

Name:	glgB
Ordered Locus Names:	CTA_0946

Organism

Chlamydia trachomatis serovar A (strain HAR-13 / ATCC VR-571B) [Complete proteome] [HAMAP]

Taxonomic identifier

315277 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydia

Protein attributes

Sequence length	738 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position By similarity. HAMAP MF_00685
Catalytic activity	Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain. HAMAP MF_00685
Pathway	Glycan biosynthesis; glycogen biosynthesis. HAMAP MF_00685
Subunit structure	Monomer By similarity. HAMAP MF_00685
Sequence similarities	Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.

Ontologies

Keywords
Biological process	Carbohydrate metabolism Glycogen biosynthesis Glycogen metabolism
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	1,4-alpha-glucan branching enzyme activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 738	738	1,4-alpha-glucan branching enzyme GlgB HAMAP MF_00685		PRO_0000260642
Sites
	Active site	399	1	Nucleophile By similarity
	Active site	452	1	Proton donor By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q3KKH0 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: E99C18FDB412A4BE	FASTA	738	84,649
	10 20 30 40 50 60 MDPFFLNTQH VELLVSGKQS SPQDLLGIVS ESLNQDRIVL FRPGAETVFV ELRGKIQQAE 70 80 90 100 110 120 SHHSGIFSLP VMKGISPQDY RVYHQNGLLA HDPYAFPLLW GEIDSFLFHE GTHQRIYERM 130 140 150 160 170 180 GAIPCEIDGV PGVRFIVWAP HAQRVSVIGD FNGWHGLVNP LHKVSDQGVW ELFVPGLTAG 190 200 210 220 230 240 ACYKWEMVTE SGQVLIKSDP YGKFFGPPPR SVSVVIDDSY EWTDSEWLEE RIKKTEGPMN 250 260 270 280 290 300 IYEVHVGSWR WQEGQPLNYR ELADQLALYC KQMHYTHVEL LPVTEHPLNE SWGYQTTGYY 310 320 330 340 350 360 APTSRYGSFE DLQYFIDTMH QHGIGVILDW VPGHFPIDSF AMSGFDGTPL YEYTRNPSPL 370 380 390 400 410 420 HPHWHTYTFD YAKPEVCNFL LGSVLFWIDK MHVDGIRVDA VSSMLYLDYG RYAGEWVPNR 430 440 450 460 470 480 YGGRENLDAI RFLQQFNTVI HEKYPGVLTF AEESTTFPKI TVSVEEGGLG FDYKWNMGWM 490 500 510 520 530 540 HDTLHYFEKD FPYRPYHQSD LTFPQWYAFS ERFLLPFSHD EVVHGKRSLI GKMPGDAWRQ 550 560 570 580 590 600 FAQLRLLLGY QICQPGKKLL FMGGEFGQGR EWSPGRELDW ELLDISYHQG VHLCSQELNA 610 620 630 640 650 660 LYVQSPQLWQ ADHLPSSFRW VDFSDVRNGV VAYLRFADAD AKKALLCVHH FGVGYFPHYL 670 680 690 700 710 720 LPILPLESCD LLMNTDDTRF GGSGKGFREP EILTPEIARQ EREAAGLIEA DDESGPDCWG 730 LDIELPPSAT LIFSVTLQ

References

[1]

"Comparative genomic analysis of Chlamydia trachomatis oculotropic and genitotropic strains." Carlson J.H., Porcella S.F., McClarty G., Caldwell H.D. Infect. Immun. 73:6407-6418(2005) [PubMed: 16177312] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: HAR-13 / ATCC VR-571B.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CP000051 Genomic DNA. Translation: AAX51152.1.
RefSeq	YP_328700.1. NC_007429.1.
3D structure databases
ProteinModelPortal	Q3KKH0.
ModBase	Search...
Protein-protein interaction databases
STRING	Q3KKH0.
Protein family/group databases
CAZy	CBM48. Carbohydrate-Binding Module Family 48. GH13. Glycoside Hydrolase Family 13.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3687552.
GenomeReviews	Gene locus CTA_0946 in contig CP000051_GR.
KEGG	cta:CTA_0946.
PATRIC	32023850. VBIChlTra31516_0964.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0296.
HOGENOM	HBG287139.
OMA	RVYHQNG.
PhylomeDB	Q3KKH0.
ProtClustDB	PRK05402.
Family and domain databases
HAMAP	MF_00685. GlgB. [Tree]
InterPro	IPR006407. 1-4-A-glucan_branch_enz. IPR006048. A-amylase_b_C. IPR015902. Alpha_amylase. IPR013780. Glyco_hydro_13_b. IPR006047. Glyco_hydro_13_cat_dom. IPR004193. Glyco_hydro_13_N. IPR013781. Glyco_hydro_subgr_catalytic. IPR017853. Glycoside_hydrolase_SF. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. [Graphical view]
Gene3D	G3DSA:2.60.40.1180. Glyco_hydro_13_b. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit. G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
KO	K00700.
PANTHER	PTHR10357. Alpha_amylase. 1 hit. PTHR10357:SF13. PTHR10357:SF13. 1 hit.
Pfam	PF00128. Alpha-amylase. 1 hit. PF02806. Alpha-amylase_C. 1 hit. PF02922. CBM_48. 1 hit. [Graphical view]
PIRSF	PIRSF000463. GlgB. 1 hit.
SUPFAM	SSF51445. Glyco_hydro_cat. 1 hit. SSF81296. Ig_E-set. 2 hits.
TIGRFAMs	TIGR01515. Branching_enzym. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLGB_CHLTA

Accession

Primary (citable) accession number: Q3KKH0

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 28, 2006
Last sequence update:	November 8, 2005
Last modified:	January 25, 2012
This is version 55 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program