Reviewed, UniProtKB/Swiss-Prot Q3KKE0 (HEM6_PSEPF)

Names and origin

Protein names

Recommended name:
    Coproporphyrinogen III oxidase, aerobic
      Short name=Coproporphyrinogenase
      Short name=Coprogen oxidase
    EC=1.3.3.3

Gene names

Name:	hemF
Ordered Locus Names:	Pfl01_0022

Organism

Pseudomonas fluorescens (strain PfO-1) [Complete proteome] [HAMAP]

Taxonomic identifier

205922 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length	304 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Coproporphyrinogen-III + O(2) + 2 H(+) = protoporphyrinogen-IX + 2 CO(2) + 2 H(2)O.
Pathway	Porphyrin metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen III (O2 route): step 1/1.
Subcellular location	CytoplasmBy similarity.
Sequence similarities	Belongs to the aerobic coproporphyrinogen III oxidase family.

Ontologies

Keywords
Biological process	Porphyrin biosynthesis
Cellular component	Cytoplasm
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW porphyrin biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: HAMAP
Molecular function	coproporphyrinogen oxidase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 304	304	Coproporphyrinogen III oxidase, aerobic		PRO_1000019489

Sequences

	Sequence		Length	Mass (Da)
	Q3KKE0-1 [UniParc]. Last modified November 8, 2005. Version 1. Checksum: 564ECF3E8DD3C1A3	FASTA	304	34,646
	10 20 30 40 50 60 MTTRTDAVKA YLLDLQDRIC AALETEDGGT RFVEDAWTRP AGGGGRTRVI ENGTVIEKGG 70 80 90 100 110 120 VNFSHVFGSG LPPSASAHRP ELAGRGFEAL GVSLVIHPHN PHVPTSHANV RFFIAEKEGE 130 140 150 160 170 180 EPVWWFGGGF DLTPYYGNEE DCIHWHRVAE KACAPFGPDV YPRYKAWCDT YFHIKHRHEP 190 200 210 220 230 240 RGIGGLFFDD LNEWDFDTSF AFMRAIGDAY IDAYLPIVQR RKNDAFTARQ REFQEFRRGR 250 260 270 280 290 300 YVEFNLVYDR GTLFGLQSGG RTESILMSLP PQVRWAYDWK AEPGSEEARL TEYFLQDRDW LAQA

References

[1]

"Complete sequence of Pseudomonas fluorescens PfO-1." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyripides N., Anderson I., Richardson P. Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000094 Genomic DNA. Translation: ABA71766.1.
RefSeq	YP_345755.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3717641.
GenomeReviews	Gene locus Pfl01_0022 in contig CP000094_GR.
KEGG	pfo:PflO1_0022.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q3KKE0.
Enzyme and pathway databases
BioCyc	PFLU205922:PFL_0022-MON.
Family and domain databases
HAMAP	MF_00333. [Tree]
InterPro	IPR001260. Coprogen_oxidas. [Graphical view]
Gene3D	G3DSA:3.40.1500.10. Coprogen_oxidas. 1 hit.
PANTHER	PTHR10755. Coprogen_oxidas. 1 hit.
Pfam	PF01218. Coprogen_oxidas. 1 hit. [Graphical view]
PIRSF	PIRSF000166. Coproporphyri_ox. 1 hit.
PRINTS	PR00073. COPRGNOXDASE.
PROSITE	PS01021. COPROGEN_OXIDASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

HEM6_PSEPF

Accession

Primary (citable) accession number: Q3KKE0

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	November 8, 2005
Last modified:	November 25, 2008
This is version 27 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)