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Q3KJB3 (SYR_PSEPF) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase
EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:Pfl01_0399
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length578 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 578578Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242070

Regions

Motif127 – 13711"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q3KJB3 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 21256ACAC4321F2F

FASTA57863,659
        10         20         30         40         50         60 
MKDTIRQLIQ QALTQLVNEG VLPEGLTPAI QVENARDKTH GDFASNIAMM LAKPAGMKPR 

        70         80         90        100        110        120 
DLAEKIIAAL PADENVTKAE IAGPGFINFF QNTQALASRL DAALADAHVG VRKAGPAQRT 

       130        140        150        160        170        180 
VVDLSAPNLA KEMHVGHLRS TIIGDGVARV LEFLGDTVIR QNHVGDWGTQ FGMLMAYLQE 

       190        200        210        220        230        240 
NPITSDELSD LENFYRAAKQ RFDESPEFAD RARGLVVKLQ AGDAECLALW TKFKDISLSH 

       250        260        270        280        290        300 
CQKIYELLNV KLTMADVMGE SAYNDDLINV VNDLKAAGML VESNGAQCVF LDEFKNAEGE 

       310        320        330        340        350        360 
PLPVIIVKAD GGYLYATTDL AAVRYRSGKL KADRALYFVD QRQALHFQQV FAVARKAGFV 

       370        380        390        400        410        420 
THPMEMEHMG FGTMNGADGR PFKTRDGGTV KLIDLLTEAQ ERAYALVKEK NPTLADDELR 

       430        440        450        460        470        480 
SIAKVVGIGA VKYADLSKHR TSDYSFNFDQ MLNLEGNTAP YLLYAYTRVA GVFRKLEKEY 

       490        500        510        520        530        540 
SEVDGQIVLE APQEHDLAAK LAQFGEVLNN VAEKGTPHTL CTYLYEVAGL FSSFYEKCPI 

       550        560        570 
LTAETPAQMQ SRLRLAALTG RTLKQGLELL GLETLERM

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000094 Genomic DNA. Translation: ABA72143.1.
RefSeqYP_346132.1. NC_007492.2.

3D structure databases

ProteinModelPortalQ3KJB3.
ModBaseSearch...

Protein-protein interaction databases

STRING205922.Pfl01_0399.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA72143; ABA72143; Pfl01_0399.
GeneID3712485.
KEGGpfo:Pfl01_0399.
PATRIC19882831. VBIPseFlu44242_0402.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
HOGENOMHOG000247212.
KOK01887.
OMARIVLDHE.
ProtClustDBPRK01611.

Enzyme and pathway databases

BioCycPFLU205922:GJBD-407-MONOMER.

Family and domain databases

Gene3D3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001412. aa-tRNA-synth_I_CS.
IPR001278. Arg-tRNA-ligase_Ia.
IPR015945. Arg-tRNA-synth_Ia_core.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF55190. Arg-tRNA-synth_Ic_N. 1 hit.
SSF47323. tRNAsyn_1a_bind. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
PROSITEPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSYR_PSEPF
AccessionPrimary (citable) accession number: Q3KJB3
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 8, 2005
Last modified: May 1, 2013
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries

SIMILARITY comments

Index of protein domains and families

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