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Q3KIW4

- PNCB_PSEPF

UniProt

Q3KIW4 - PNCB_PSEPF

Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 76 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

    Catalytic activityi

    Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. ligase activity Source: UniProtKB-KW
    2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
    3. nicotinate phosphoribosyltransferase activity Source: InterPro

    GO - Biological processi

    1. NAD biosynthetic process Source: UniProtKB-UniPathway
    2. nicotinate nucleotide biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    Ligase, Transferase

    Keywords - Biological processi

    Pyridine nucleotide biosynthesis

    Enzyme and pathway databases

    BioCyciPFLU205922:GJBD-558-MONOMER.
    UniPathwayiUPA00253; UER00457.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
    Short name:
    NAPRTaseUniRule annotation
    Gene namesi
    Name:pncBUniRule annotation
    Ordered Locus Names:Pfl01_0548
    OrganismiPseudomonas fluorescens (strain Pf0-1)
    Taxonomic identifieri205922 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002704: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 407407Nicotinate phosphoribosyltransferasePRO_1000025007Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi205922.Pfl01_0548.

    Structurei

    3D structure databases

    ProteinModelPortaliQ3KIW4.
    SMRiQ3KIW4. Positions 1-397.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the NAPRTase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG1488.
    HOGENOMiHOG000284928.
    KOiK00763.
    OMAiQAVFHRY.
    OrthoDBiEOG6X10XB.

    Family and domain databases

    HAMAPiMF_00570. NAPRTase.
    InterProiIPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view]
    PANTHERiPTHR11098. PTHR11098. 1 hit.
    PfamiPF04095. NAPRTase. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000484. NAPRT. 1 hit.
    SUPFAMiSSF51690. SSF51690. 1 hit.
    TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q3KIW4-1 [UniParc]FASTAAdd to Basket

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    MSESVFADRI VQNLLDTDFY KLTMMQAVLH NYPNVEVEWE FRCRNSEDLR    50
    PYLAEIRFQV ERLAELSLSA DQLSFLERIS FLKPDFLRFL GLFRFNLRYL 100
    HTGIENGELF IRLRGPWLHV ILFEVPLLAI VSEVRNRYRY RETVLEQARE 150
    QLYRKFDWLT ANASAEELSQ LQVADFGTRR RFSYRVQEEV VNVLKHDFPG 200
    RFVGTSNVHL SRELDMKPLG TMAHEWIMAH QQLGPRLIDS QIAALDCWVR 250
    EYRGLLGIAL TDCITTDAFL GDFDLFFAKL FDGLRHDSGD PVLWGEKCIA 300
    HYHKLGIDPM SKTLVFSDSL TLPKSLEIFR ALRGRINVSF GIGTNLTCDI 350
    PGVEPMSIVL KMTACNGQPV AKISDEPGKT HCKDPNFVAY LRHVFQVPAV 400
    SSLSSKE 407
    Length:407
    Mass (Da):46,872
    Last modified:November 8, 2005 - v1
    Checksum:i3194946C703E7918
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000094 Genomic DNA. Translation: ABA72292.1.
    RefSeqiWP_011332202.1. NC_007492.2.
    YP_346281.1. NC_007492.2.

    Genome annotation databases

    EnsemblBacteriaiABA72292; ABA72292; Pfl01_0548.
    GeneIDi3712943.
    KEGGipfo:Pfl01_0548.
    PATRICi19883145. VBIPseFlu44242_0557.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000094 Genomic DNA. Translation: ABA72292.1 .
    RefSeqi WP_011332202.1. NC_007492.2.
    YP_346281.1. NC_007492.2.

    3D structure databases

    ProteinModelPortali Q3KIW4.
    SMRi Q3KIW4. Positions 1-397.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 205922.Pfl01_0548.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA72292 ; ABA72292 ; Pfl01_0548 .
    GeneIDi 3712943.
    KEGGi pfo:Pfl01_0548.
    PATRICi 19883145. VBIPseFlu44242_0557.

    Phylogenomic databases

    eggNOGi COG1488.
    HOGENOMi HOG000284928.
    KOi K00763.
    OMAi QAVFHRY.
    OrthoDBi EOG6X10XB.

    Enzyme and pathway databases

    UniPathwayi UPA00253 ; UER00457 .
    BioCyci PFLU205922:GJBD-558-MONOMER.

    Family and domain databases

    HAMAPi MF_00570. NAPRTase.
    InterProi IPR006406. Nic_PRibTrfase.
    IPR007229. Nic_PRibTrfase-Fam.
    IPR002638. Quinolinate_PRibosylTrfase_C.
    [Graphical view ]
    PANTHERi PTHR11098. PTHR11098. 1 hit.
    Pfami PF04095. NAPRTase. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000484. NAPRT. 1 hit.
    SUPFAMi SSF51690. SSF51690. 1 hit.
    TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Pf0-1.

    Entry informationi

    Entry nameiPNCB_PSEPF
    AccessioniPrimary (citable) accession number: Q3KIW4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: January 15, 2008
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3