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Q3KIW4

- PNCB_PSEPF

UniProt

Q3KIW4 - PNCB_PSEPF

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Protein

Nicotinate phosphoribosyltransferase

Gene

pncB

Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP.UniRule annotation

Catalytic activityi

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ligase activity Source: UniProtKB-KW
  2. nicotinate-nucleotide diphosphorylase (carboxylating) activity Source: InterPro
  3. nicotinate phosphoribosyltransferase activity Source: InterPro

GO - Biological processi

  1. NAD biosynthetic process Source: UniProtKB-UniPathway
  2. nicotinate nucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Ligase, Transferase

Keywords - Biological processi

Pyridine nucleotide biosynthesis

Enzyme and pathway databases

BioCyciPFLU205922:GJBD-558-MONOMER.
UniPathwayiUPA00253; UER00457.

Names & Taxonomyi

Protein namesi
Recommended name:
Nicotinate phosphoribosyltransferaseUniRule annotation (EC:6.3.4.21UniRule annotation)
Short name:
NAPRTaseUniRule annotation
Gene namesi
Name:pncBUniRule annotation
Ordered Locus Names:Pfl01_0548
OrganismiPseudomonas fluorescens (strain Pf0-1)
Taxonomic identifieri205922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002704: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 407407Nicotinate phosphoribosyltransferasePRO_1000025007Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi205922.Pfl01_0548.

Structurei

3D structure databases

ProteinModelPortaliQ3KIW4.
SMRiQ3KIW4. Positions 1-397.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NAPRTase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG1488.
HOGENOMiHOG000284928.
KOiK00763.
OMAiQAVFHRY.
OrthoDBiEOG6X10XB.

Family and domain databases

HAMAPiMF_00570. NAPRTase.
InterProiIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERiPTHR11098. PTHR11098. 1 hit.
PfamiPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFiPIRSF000484. NAPRT. 1 hit.
SUPFAMiSSF51690. SSF51690. 1 hit.
TIGRFAMsiTIGR01514. NAPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3KIW4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSESVFADRI VQNLLDTDFY KLTMMQAVLH NYPNVEVEWE FRCRNSEDLR
60 70 80 90 100
PYLAEIRFQV ERLAELSLSA DQLSFLERIS FLKPDFLRFL GLFRFNLRYL
110 120 130 140 150
HTGIENGELF IRLRGPWLHV ILFEVPLLAI VSEVRNRYRY RETVLEQARE
160 170 180 190 200
QLYRKFDWLT ANASAEELSQ LQVADFGTRR RFSYRVQEEV VNVLKHDFPG
210 220 230 240 250
RFVGTSNVHL SRELDMKPLG TMAHEWIMAH QQLGPRLIDS QIAALDCWVR
260 270 280 290 300
EYRGLLGIAL TDCITTDAFL GDFDLFFAKL FDGLRHDSGD PVLWGEKCIA
310 320 330 340 350
HYHKLGIDPM SKTLVFSDSL TLPKSLEIFR ALRGRINVSF GIGTNLTCDI
360 370 380 390 400
PGVEPMSIVL KMTACNGQPV AKISDEPGKT HCKDPNFVAY LRHVFQVPAV

SSLSSKE
Length:407
Mass (Da):46,872
Last modified:November 8, 2005 - v1
Checksum:i3194946C703E7918
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000094 Genomic DNA. Translation: ABA72292.1.
RefSeqiWP_011332202.1. NC_007492.2.
YP_346281.1. NC_007492.2.

Genome annotation databases

EnsemblBacteriaiABA72292; ABA72292; Pfl01_0548.
GeneIDi3712943.
KEGGipfo:Pfl01_0548.
PATRICi19883145. VBIPseFlu44242_0557.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000094 Genomic DNA. Translation: ABA72292.1 .
RefSeqi WP_011332202.1. NC_007492.2.
YP_346281.1. NC_007492.2.

3D structure databases

ProteinModelPortali Q3KIW4.
SMRi Q3KIW4. Positions 1-397.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 205922.Pfl01_0548.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA72292 ; ABA72292 ; Pfl01_0548 .
GeneIDi 3712943.
KEGGi pfo:Pfl01_0548.
PATRICi 19883145. VBIPseFlu44242_0557.

Phylogenomic databases

eggNOGi COG1488.
HOGENOMi HOG000284928.
KOi K00763.
OMAi QAVFHRY.
OrthoDBi EOG6X10XB.

Enzyme and pathway databases

UniPathwayi UPA00253 ; UER00457 .
BioCyci PFLU205922:GJBD-558-MONOMER.

Family and domain databases

HAMAPi MF_00570. NAPRTase.
InterProi IPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view ]
PANTHERi PTHR11098. PTHR11098. 1 hit.
Pfami PF04095. NAPRTase. 1 hit.
[Graphical view ]
PIRSFi PIRSF000484. NAPRT. 1 hit.
SUPFAMi SSF51690. SSF51690. 1 hit.
TIGRFAMsi TIGR01514. NAPRTase. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pf0-1.

Entry informationi

Entry nameiPNCB_PSEPF
AccessioniPrimary (citable) accession number: Q3KIW4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 8, 2005
Last modified: October 1, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3