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Q3KIW4 (PNCB_PSEPF) Reviewed, UniProtKB/Swiss-Prot

Last modified March 19, 2014. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:Pfl01_0548
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 407407Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000025007

Sequences

Sequence LengthMass (Da)Tools
Q3KIW4 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 3194946C703E7918

FASTA40746,872
        10         20         30         40         50         60 
MSESVFADRI VQNLLDTDFY KLTMMQAVLH NYPNVEVEWE FRCRNSEDLR PYLAEIRFQV 

        70         80         90        100        110        120 
ERLAELSLSA DQLSFLERIS FLKPDFLRFL GLFRFNLRYL HTGIENGELF IRLRGPWLHV 

       130        140        150        160        170        180 
ILFEVPLLAI VSEVRNRYRY RETVLEQARE QLYRKFDWLT ANASAEELSQ LQVADFGTRR 

       190        200        210        220        230        240 
RFSYRVQEEV VNVLKHDFPG RFVGTSNVHL SRELDMKPLG TMAHEWIMAH QQLGPRLIDS 

       250        260        270        280        290        300 
QIAALDCWVR EYRGLLGIAL TDCITTDAFL GDFDLFFAKL FDGLRHDSGD PVLWGEKCIA 

       310        320        330        340        350        360 
HYHKLGIDPM SKTLVFSDSL TLPKSLEIFR ALRGRINVSF GIGTNLTCDI PGVEPMSIVL 

       370        380        390        400 
KMTACNGQPV AKISDEPGKT HCKDPNFVAY LRHVFQVPAV SSLSSKE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000094 Genomic DNA. Translation: ABA72292.1.
RefSeqYP_346281.1. NC_007492.2.

3D structure databases

ProteinModelPortalQ3KIW4.
SMRQ3KIW4. Positions 1-397.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING205922.Pfl01_0548.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA72292; ABA72292; Pfl01_0548.
GeneID3712943.
KEGGpfo:Pfl01_0548.
PATRIC19883145. VBIPseFlu44242_0557.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284928.
KOK00763.
OMAKLTMQCA.
OrthoDBEOG6X10XB.
ProtClustDBPRK05321.

Enzyme and pathway databases

BioCycPFLU205922:GJBD-558-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_PSEPF
AccessionPrimary (citable) accession number: Q3KIW4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 8, 2005
Last modified: March 19, 2014
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways