ID   ADD_PSEPF               Reviewed;         317 AA.
AC   Q3KIJ1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   16-JUN-2009, entry version 29.
DE   RecName: Full=Adenosine deaminase;
DE            EC=3.5.4.4;
DE   AltName: Full=Adenosine aminohydrolase;
GN   Name=add; OrderedLocusNames=Pfl01_0671;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyripides N., Anderson I., Richardson P.;
RT   "Complete sequence of Pseudomonas fluorescens PfO-1.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: Adenosine + H(2)O = inosine + NH(3).
CC   -!- SIMILARITY: Belongs to the adenosine and AMP deaminases family.
CC   -----------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution-NoDerivs License
CC   -----------------------------------------------------------------------
DR   EMBL; CP000094; ABA72415.1; -; Genomic_DNA.
DR   RefSeq; YP_346404.1; -.
DR   GeneID; 3713956; -.
DR   GenomeReviews; CP000094_GR; Pfl01_0671.
DR   KEGG; pfo:Pfl01_0671; -.
DR   HOGENOM; Q3KIJ1; -.
DR   OMA; Q3KIJ1; LAQNSLD.
DR   BioCyc; PFLU205922:PFL_0671-MON; -.
DR   GO; GO:0004000; F:adenosine deaminase activity; IEA:HAMAP.
DR   GO; GO:0009168; P:purine ribonucleoside monophosphate biosynt...; IEA:HAMAP.
DR   HAMAP; MF_00540; -; 1.
DR   InterPro; IPR006650; A/AMP_deam_AS.
DR   InterPro; IPR001365; A/AMP_deaminase.
DR   InterPro; IPR006330; A_deaminase.
DR   PANTHER; PTHR11409; A/AMP_deaminase; 1.
DR   Pfam; PF00962; A_deaminase; 1.
DR   TIGRFAMs; TIGR01430; aden_deam; 1.
DR   PROSITE; PS00485; A_DEAMINASE; FALSE_NEG.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase; Nucleotide metabolism.
FT   CHAIN         1    317       Adenosine deaminase.
FT                                /FTId=PRO_1000017683.
FT   ACT_SITE    194    194       Potential.
FT   ACT_SITE    242    242       Potential.
FT   ACT_SITE    275    275       Potential.
FT   ACT_SITE    276    276       Potential.
SQ   SEQUENCE   317 AA;  36177 MW;  A669E6829F6B3D90 CRC64;
     MYDWLNALPK AELHLHLEGS LEPELLFALA ERNKIALPWS DVETLRKAYA FNNLQEFLDL
     YYQGADVLRT SQDFYDLTWA YLLRCKEQNV IHTEPFFDPQ THTDRGIPFE VVLNGIAAAL
     KDGEQQLGIT SGLILSFLRH LSEDEAQKTL DQALPFRDAF VAVGLDSSEM GHPPSKFQRV
     FDRARHEGFL TVAHAGEEGP PEYIWEAIDL LKIQRIDHGV RAIEDERLMQ RIIDEQIPLT
     VCPLSNTKLC VFDHMSQHNI LDMLERGVKV TVNSDDPAYF GGYVTENFHA LHEHLGMTQD
     QAKRLAQNSL DARLVKP
//