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Q3KFT0

- PUR5_PSEPF

UniProt

Q3KFT0 - PUR5_PSEPF

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, Pfl01_1633
Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciPFLU205922:GJBD-1656-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:Pfl01_1633
OrganismiPseudomonas fluorescens (strain Pf0-1)
Taxonomic identifieri205922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002704: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 352352Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_0000258384Add
BLAST

Proteomic databases

PRIDEiQ3KFT0.

Interactioni

Protein-protein interaction databases

STRINGi205922.Pfl01_1633.

Structurei

3D structure databases

ProteinModelPortaliQ3KFT0.
SMRiQ3KFT0. Positions 6-337.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3KFT0-1 [UniParc]FASTAAdd to Basket

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MSKQPSLSYK DAGVDIDAGE ALVERIKSVA KRTARPEVMG GLGGFGALCE    50
IPAGYKQPVL VSGTDGVGTK LRLALNLNKH DSIGQDLVAM CVNDLVVCGA 100
EPLFFLDYYA TGKLNVDVAA TVVTGIGAGC ELAGCSLVGG ETAEMPGMYE 150
GEDYDLAGFC VGVVEKAEII DGSKVATGDA LIALPSSGPH SNGYSLIRKI 200
IEVSGADIET VQLDGKPLTE LLMAPTRIYV KPLLKLIKDT GAVKAMAHIT 250
GGGLLDNIPR VLPKGAQAVV DVASWNRPAV FDWLQEKGNV DETEMHRVLN 300
CGVGMVICVA QEHVEVALNT LRDAGEQPWV IGQIAAAAEG AAQVELKNLK 350
AH 352
Length:352
Mass (Da):36,860
Last modified:November 8, 2005 - v1
Checksum:i15802DECAC418E89
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000094 Genomic DNA. Translation: ABA73376.1.
RefSeqiYP_347365.1. NC_007492.2.

Genome annotation databases

EnsemblBacteriaiABA73376; ABA73376; Pfl01_1633.
GeneIDi3716806.
KEGGipfo:Pfl01_1633.
PATRICi19885379. VBIPseFlu44242_1663.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CP000094 Genomic DNA. Translation: ABA73376.1 .
RefSeqi YP_347365.1. NC_007492.2.

3D structure databases

ProteinModelPortali Q3KFT0.
SMRi Q3KFT0. Positions 6-337.
ModBasei Search...

Protein-protein interaction databases

STRINGi 205922.Pfl01_1633.

Proteomic databases

PRIDEi Q3KFT0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA73376 ; ABA73376 ; Pfl01_1633 .
GeneIDi 3716806.
KEGGi pfo:Pfl01_1633.
PATRICi 19885379. VBIPseFlu44242_1663.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci PFLU205922:GJBD-1656-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pf0-1.

Entry informationi

Entry nameiPUR5_PSEPF
AccessioniPrimary (citable) accession number: Q3KFT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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