ID   XYLA_PSEPF              Reviewed;         438 AA.
AC   Q3KDW0;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   16-JUN-2009, entry version 32.
DE   RecName: Full=Xylose isomerase;
DE            EC=5.3.1.5;
GN   Name=xylA; OrderedLocusNames=Pfl01_2303;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyripides N., Anderson I., Richardson P.;
RT   "Complete sequence of Pseudomonas fluorescens PfO-1.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY: D-xylose = D-xylulose.
CC   -!- COFACTOR: Binds 2 magnesium ions per subunit (By similarity).
CC   -!- SUBUNIT: Homotetramer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the xylose isomerase family.
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DR   EMBL; CP000094; ABA74046.1; -; Genomic_DNA.
DR   RefSeq; YP_348035.1; -.
DR   GeneID; 3715586; -.
DR   GenomeReviews; CP000094_GR; Pfl01_2303.
DR   KEGG; pfo:Pfl01_2303; -.
DR   HOGENOM; Q3KDW0; -.
DR   OMA; Q3KDW0; QFLIEPK.
DR   BioCyc; PFLU205922:PFL_2303-MON; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:HAMAP.
DR   GO; GO:0009045; F:xylose isomerase activity; IEA:HAMAP.
DR   GO; GO:0042732; P:D-xylose metabolic process; IEA:HAMAP.
DR   GO; GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP.
DR   HAMAP; MF_00455; -; 1.
DR   InterPro; IPR013022; Xyl_isomerase-like_TIM-brl.
DR   InterPro; IPR012307; Xyl_isomerase-typ_TIM-brl.
DR   InterPro; IPR013452; Xylose_isom_bac.
DR   InterPro; IPR001998; Xylose_isomerase.
DR   InterPro; IPR018115; Xylose_isomerase_AS.
DR   Gene3D; G3DSA:3.20.20.150; Xyl_isomerase-like_TIM-brl; 1.
DR   Pfam; PF01261; AP_endonuc_2; 1.
DR   PRINTS; PR00688; XYLOSISMRASE.
DR   TIGRFAMs; TIGR02630; xylose_isom_A; 1.
DR   PROSITE; PS51415; XYLOSE_ISOMERASE; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Cytoplasm; Isomerase;
KW   Magnesium; Metal-binding; Pentose shunt; Xylose metabolism.
FT   CHAIN         1    438       Xylose isomerase.
FT                                /FTId=PRO_0000236966.
FT   ACT_SITE    100    100       By similarity.
FT   ACT_SITE    103    103       By similarity.
FT   METAL       231    231       Magnesium 1 (By similarity).
FT   METAL       267    267       Magnesium 1 (By similarity).
FT   METAL       267    267       Magnesium 2 (By similarity).
FT   METAL       270    270       Magnesium 2 (By similarity).
FT   METAL       295    295       Magnesium 1 (By similarity).
FT   METAL       306    306       Magnesium 2 (By similarity).
FT   METAL       308    308       Magnesium 2 (By similarity).
FT   METAL       338    338       Magnesium 1 (By similarity).
SQ   SEQUENCE   438 AA;  49447 MW;  79AE75129BD04827 CRC64;
     MPYFPDIERI RYEGPASDSP LAFRHYDADK IILGKPMREH LRMAACYWHT FVWPGSDVFG
     AGTFKRPWQH AGDPMELAIG KAQAAFEFFS KLGIDYYCFH DTDVAPEGNS LKEYRNHFAQ
     MIDHLERHQE ESGIKLLWGT ANCFSNPRFA AGAASNPDPE VFACAAAQVF SAMNATQRLK
     GANYVLWGGR EGYETLLNTD LKREREQLGR FMRMVVEHKY KIGFKGDLLI EPKPQEPTKH
     QYDYDSATVF GFLQQFGLEK EIKVNIEANH ATLAGHSFHH EVATAVSLGI FGSIDANRGD
     PQNGWDTDQF PNSVEEMTLV TYEILKAGGF GNGGFNFDSK VRRQSLDETD LFHGHVGAMD
     VLALSLERAA AMVQNDQLQR LKDQRYAGWQ QPFGQSVLAG DFNLQSLAEH AFANELNPQA
     VSGRQEMLEN VVNRFIYR
//