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Q3KD12 (UPPP1_PSEPF) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 1

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 1
Undecaprenyl pyrophosphate phosphatase 1
Gene names
Name:uppP1
Ordered Locus Names:Pfl01_2602
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length276 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 276276Undecaprenyl-diphosphatase 1 HAMAP-Rule MF_01006
PRO_0000227630

Regions

Transmembrane43 – 6321Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane109 – 12921Helical; Potential
Transmembrane184 – 20421Helical; Potential
Transmembrane214 – 23421Helical; Potential
Transmembrane254 – 27421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3KD12 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 95C1D6E85B689355

FASTA27630,315
        10         20         30         40         50         60 
MDLWTALQAL ILGVVEGLTE FLPISSTGHQ IIVADLLDFG GERAMAFNII IQLGAILAVV 

        70         80         90        100        110        120 
WEFRRKILDV VIGLPTQPSA RRFTANLLIA FLPAVVLGVI FADLIHHYLF NPITVAAALV 

       130        140        150        160        170        180 
VGGIVMLWAE QRQHEVHAET VDEIRWTDAL KIGFAQCLAM IPGTSRSGST IIGGLLFGLS 

       190        200        210        220        230        240 
RKTATEFSFF LAMPTMVGAA VYSGYKYRDL FVPADFPVFA IGFVTAFIFA MIAVRGLLKF 

       250        260        270 
IGSHSYAAFA WYRIVFGLVI LATWQFGWVD WTAAQP 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000094 Genomic DNA. Translation: ABA74343.1.
RefSeqYP_348333.1. NC_007492.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING205922.Pfl01_2602.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA74343; ABA74343; Pfl01_2602.
GeneID3714203.
KEGGpfo:Pfl01_2602.
PATRIC19887371. VBIPseFlu44242_2637.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMAMEIGTIF.
OrthoDBEOG6QP13M.

Enzyme and pathway databases

BioCycPFLU205922:GJBD-2648-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP1_PSEPF
AccessionPrimary (citable) accession number: Q3KD12
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 8, 2005
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families