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Q3KCB9

- ARNT2_PSEPF

UniProt

Q3KCB9 - ARNT2_PSEPF

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Protein

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

Gene

arnT2

Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotation

Catalytic activityi

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. mannosyltransferase activity Source: InterPro
  2. transferase activity, transferring pentosyl groups Source: InterPro

GO - Biological processi

  1. lipid A biosynthetic process Source: UniProtKB-HAMAP
  2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
  3. protein O-linked glycosylation Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesis

Enzyme and pathway databases

BioCyciPFLU205922:GJBD-2891-MONOMER.
UniPathwayiUPA00037.

Protein family/group databases

CAZyiGT83. Glycosyltransferase Family 83.

Names & Taxonomyi

Protein namesi
Recommended name:
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2UniRule annotation (EC:2.4.2.43UniRule annotation)
Alternative name(s):
4-amino-4-deoxy-L-arabinose lipid A transferase 2UniRule annotation
Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation
Undecaprenyl phosphate-alpha-L-Ara4N transferase 2UniRule annotation
Gene namesi
Name:arnT2UniRule annotation
Ordered Locus Names:Pfl01_2845
OrganismiPseudomonas fluorescens (strain Pf0-1)
Taxonomic identifieri205922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
ProteomesiUP000002704: Chromosome

Subcellular locationi

Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei9 – 2921HelicalUniRule annotationAdd
BLAST
Transmembranei80 – 10223HelicalUniRule annotationAdd
BLAST
Transmembranei112 – 13221HelicalUniRule annotationAdd
BLAST
Transmembranei133 – 15321HelicalUniRule annotationAdd
BLAST
Transmembranei176 – 19621HelicalUniRule annotationAdd
BLAST
Transmembranei204 – 22421HelicalUniRule annotationAdd
BLAST
Transmembranei259 – 27921HelicalUniRule annotationAdd
BLAST
Transmembranei290 – 31021HelicalUniRule annotationAdd
BLAST
Transmembranei312 – 33221HelicalUniRule annotationAdd
BLAST
Transmembranei342 – 36221HelicalUniRule annotationAdd
BLAST
Transmembranei377 – 39721HelicalUniRule annotationAdd
BLAST
Transmembranei402 – 42221HelicalUniRule annotationAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. plasma membrane Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cell inner membrane, Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 549549Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2PRO_0000380022Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi205922.Pfl01_2845.

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 83 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1807.
HOGENOMiHOG000273002.
KOiK07264.
OMAiGNWIAPH.
OrthoDBiEOG6NKQWN.

Family and domain databases

HAMAPiMF_01165. ArnT_transfer.
InterProiIPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view]
PfamiPF02366. PMT. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q3KCB9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSKRWALPLL LGIFLLAYLL PLGSHGLWIP DETRYAQISQ EMLLSGNWVS
60 70 80 90 100
PHFMNLRYFE KPAAGYWMIA IGQAVFGQNL FGVRFASALS TGLSVLLCFL
110 120 130 140 150
IARRLWNEPR KSFVCALLYM SFVIVAGQAG YANLDPQFTF WVNLSLVALW
160 170 180 190 200
FALDSRANGQ RLAGWAVLGL ACGMGFMTKG FLAWLLPVLI ALPWMLWQKR
210 220 230 240 250
WKELLLYGPV AIAVAIIVSL PWALAVHGQE PDYWRFFFWH EHIRRFAGDD
260 270 280 290 300
AQHDAPWWFY LPLLVAFSLP WVGMLPVAFK QAWQTRRETG IAFLGLWLLM
310 320 330 340 350
PLLFFSLSNG KLPTYILPCL LPLALLLGHA LADRLRLEQG RALGLNGLLN
360 370 380 390 400
LLLGLVTLIG LVYVQLKRPL YDHELHSLVL VFIALTGWII SNLLQAFRPL
410 420 430 440 450
QCWAAPAVGS LLLIALLPAA LPRSVVANKM PDQFVLAHQK ELTATTHLLS
460 470 480 490 500
NDLGAASALS WRVKRPQVAL YNTIGELKYG LAYPDGIQQR VDPDQVQQWM
510 520 530 540
REARKTGSVG VVMRVKGQDE LDELDRLPKD GVRYEQGNLV IMILPQEAS
Length:549
Mass (Da):61,799
Last modified:November 8, 2005 - v1
Checksum:iBE48FCA63666F866
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000094 Genomic DNA. Translation: ABA74586.1.
RefSeqiWP_011334257.1. NC_007492.2.
YP_348576.1. NC_007492.2.

Genome annotation databases

EnsemblBacteriaiABA74586; ABA74586; Pfl01_2845.
GeneIDi3712609.
KEGGipfo:Pfl01_2845.
PATRICi19887851. VBIPseFlu44242_2878.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000094 Genomic DNA. Translation: ABA74586.1 .
RefSeqi WP_011334257.1. NC_007492.2.
YP_348576.1. NC_007492.2.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 205922.Pfl01_2845.

Protein family/group databases

CAZyi GT83. Glycosyltransferase Family 83.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai ABA74586 ; ABA74586 ; Pfl01_2845 .
GeneIDi 3712609.
KEGGi pfo:Pfl01_2845.
PATRICi 19887851. VBIPseFlu44242_2878.

Phylogenomic databases

eggNOGi COG1807.
HOGENOMi HOG000273002.
KOi K07264.
OMAi GNWIAPH.
OrthoDBi EOG6NKQWN.

Enzyme and pathway databases

UniPathwayi UPA00037 .
BioCyci PFLU205922:GJBD-2891-MONOMER.

Family and domain databases

HAMAPi MF_01165. ArnT_transfer.
InterProi IPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view ]
Pfami PF02366. PMT. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Pf0-1.

Entry informationi

Entry nameiARNT2_PSEPF
AccessioniPrimary (citable) accession number: Q3KCB9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 8, 2005
Last modified: October 29, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3