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Q3KCB9

- ARNT2_PSEPF

UniProt

Q3KCB9 - ARNT2_PSEPF

Protein

Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2

Gene

arnT2

Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (08 Nov 2005)
      Previous versions | rss
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    Functioni

    Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides.UniRule annotation

    Catalytic activityi

    4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. mannosyltransferase activity Source: InterPro
    2. transferase activity, transferring pentosyl groups Source: InterPro

    GO - Biological processi

    1. lipid A biosynthetic process Source: UniProtKB-HAMAP
    2. lipopolysaccharide biosynthetic process Source: UniProtKB-KW
    3. protein O-linked glycosylation Source: InterPro

    Keywords - Molecular functioni

    Glycosyltransferase, Transferase

    Keywords - Biological processi

    Lipid A biosynthesis, Lipid biosynthesis, Lipid metabolism, Lipopolysaccharide biosynthesis

    Enzyme and pathway databases

    BioCyciPFLU205922:GJBD-2891-MONOMER.
    UniPathwayiUPA00037.

    Protein family/group databases

    CAZyiGT83. Glycosyltransferase Family 83.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2UniRule annotation (EC:2.4.2.43UniRule annotation)
    Alternative name(s):
    4-amino-4-deoxy-L-arabinose lipid A transferase 2UniRule annotation
    Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferaseUniRule annotation
    Undecaprenyl phosphate-alpha-L-Ara4N transferase 2UniRule annotation
    Gene namesi
    Name:arnT2UniRule annotation
    Ordered Locus Names:Pfl01_2845
    OrganismiPseudomonas fluorescens (strain Pf0-1)
    Taxonomic identifieri205922 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
    ProteomesiUP000002704: Chromosome

    Subcellular locationi

    Cell inner membrane UniRule annotation; Multi-pass membrane protein UniRule annotation

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell inner membrane, Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 549549Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2PRO_0000380022Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi205922.Pfl01_2845.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei9 – 2921HelicalUniRule annotationAdd
    BLAST
    Transmembranei80 – 10223HelicalUniRule annotationAdd
    BLAST
    Transmembranei112 – 13221HelicalUniRule annotationAdd
    BLAST
    Transmembranei133 – 15321HelicalUniRule annotationAdd
    BLAST
    Transmembranei176 – 19621HelicalUniRule annotationAdd
    BLAST
    Transmembranei204 – 22421HelicalUniRule annotationAdd
    BLAST
    Transmembranei259 – 27921HelicalUniRule annotationAdd
    BLAST
    Transmembranei290 – 31021HelicalUniRule annotationAdd
    BLAST
    Transmembranei312 – 33221HelicalUniRule annotationAdd
    BLAST
    Transmembranei342 – 36221HelicalUniRule annotationAdd
    BLAST
    Transmembranei377 – 39721HelicalUniRule annotationAdd
    BLAST
    Transmembranei402 – 42221HelicalUniRule annotationAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the glycosyltransferase 83 family.UniRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1807.
    HOGENOMiHOG000273002.
    KOiK07264.
    OMAiGNWIAPH.
    OrthoDBiEOG6NKQWN.

    Family and domain databases

    HAMAPiMF_01165. ArnT_transfer.
    InterProiIPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view]
    PfamiPF02366. PMT. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q3KCB9-1 [UniParc]FASTAAdd to Basket

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    MSKRWALPLL LGIFLLAYLL PLGSHGLWIP DETRYAQISQ EMLLSGNWVS    50
    PHFMNLRYFE KPAAGYWMIA IGQAVFGQNL FGVRFASALS TGLSVLLCFL 100
    IARRLWNEPR KSFVCALLYM SFVIVAGQAG YANLDPQFTF WVNLSLVALW 150
    FALDSRANGQ RLAGWAVLGL ACGMGFMTKG FLAWLLPVLI ALPWMLWQKR 200
    WKELLLYGPV AIAVAIIVSL PWALAVHGQE PDYWRFFFWH EHIRRFAGDD 250
    AQHDAPWWFY LPLLVAFSLP WVGMLPVAFK QAWQTRRETG IAFLGLWLLM 300
    PLLFFSLSNG KLPTYILPCL LPLALLLGHA LADRLRLEQG RALGLNGLLN 350
    LLLGLVTLIG LVYVQLKRPL YDHELHSLVL VFIALTGWII SNLLQAFRPL 400
    QCWAAPAVGS LLLIALLPAA LPRSVVANKM PDQFVLAHQK ELTATTHLLS 450
    NDLGAASALS WRVKRPQVAL YNTIGELKYG LAYPDGIQQR VDPDQVQQWM 500
    REARKTGSVG VVMRVKGQDE LDELDRLPKD GVRYEQGNLV IMILPQEAS 549
    Length:549
    Mass (Da):61,799
    Last modified:November 8, 2005 - v1
    Checksum:iBE48FCA63666F866
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000094 Genomic DNA. Translation: ABA74586.1.
    RefSeqiYP_348576.1. NC_007492.2.

    Genome annotation databases

    EnsemblBacteriaiABA74586; ABA74586; Pfl01_2845.
    GeneIDi3712609.
    KEGGipfo:Pfl01_2845.
    PATRICi19887851. VBIPseFlu44242_2878.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CP000094 Genomic DNA. Translation: ABA74586.1 .
    RefSeqi YP_348576.1. NC_007492.2.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 205922.Pfl01_2845.

    Protein family/group databases

    CAZyi GT83. Glycosyltransferase Family 83.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai ABA74586 ; ABA74586 ; Pfl01_2845 .
    GeneIDi 3712609.
    KEGGi pfo:Pfl01_2845.
    PATRICi 19887851. VBIPseFlu44242_2878.

    Phylogenomic databases

    eggNOGi COG1807.
    HOGENOMi HOG000273002.
    KOi K07264.
    OMAi GNWIAPH.
    OrthoDBi EOG6NKQWN.

    Enzyme and pathway databases

    UniPathwayi UPA00037 .
    BioCyci PFLU205922:GJBD-2891-MONOMER.

    Family and domain databases

    HAMAPi MF_01165. ArnT_transfer.
    InterProi IPR022839. ArnT_tfrase.
    IPR003342. Glyco_trans_39.
    [Graphical view ]
    Pfami PF02366. PMT. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Pf0-1.

    Entry informationi

    Entry nameiARNT2_PSEPF
    AccessioniPrimary (citable) accession number: Q3KCB9
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 28, 2009
    Last sequence update: November 8, 2005
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3