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Q3KCB9 (ARNT2_PSEPF) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 61. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2
EC=2.4.2.43
Alternative name(s):
4-amino-4-deoxy-L-arabinose lipid A transferase 2
Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase
Undecaprenyl phosphate-alpha-L-Ara4N transferase 2
Gene names
Name:arnT2
Ordered Locus Names:Pfl01_2845
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas ›

Protein attributes

Sequence length549 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the transfer of the L-Ara4N moiety of the glycolipid undecaprenyl phosphate-alpha-L-Ara4N to lipid A. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides By similarity. HAMAP-Rule MF_01165

Catalytic activity

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate. HAMAP-Rule MF_01165

Pathway

Lipopolysaccharide metabolism; 4-amino-4-deoxy-beta-L-arabinose-lipid A biosynthesis. HAMAP-Rule MF_01165

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01165.

Sequence similarities

Belongs to the glycosyltransferase 83 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 549549Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase 2 HAMAP-Rule MF_01165
PRO_0000380022

Regions

Transmembrane9 – 2921Helical; Potential
Transmembrane80 – 10223Helical; Potential
Transmembrane112 – 13221Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane176 – 19621Helical; Potential
Transmembrane204 – 22421Helical; Potential
Transmembrane259 – 27921Helical; Potential
Transmembrane290 – 31021Helical; Potential
Transmembrane312 – 33221Helical; Potential
Transmembrane342 – 36221Helical; Potential
Transmembrane377 – 39721Helical; Potential
Transmembrane402 – 42221Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3KCB9 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: BE48FCA63666F866

FASTA54961,799
        10         20         30         40         50         60 
MSKRWALPLL LGIFLLAYLL PLGSHGLWIP DETRYAQISQ EMLLSGNWVS PHFMNLRYFE 

        70         80         90        100        110        120 
KPAAGYWMIA IGQAVFGQNL FGVRFASALS TGLSVLLCFL IARRLWNEPR KSFVCALLYM 

       130        140        150        160        170        180 
SFVIVAGQAG YANLDPQFTF WVNLSLVALW FALDSRANGQ RLAGWAVLGL ACGMGFMTKG 

       190        200        210        220        230        240 
FLAWLLPVLI ALPWMLWQKR WKELLLYGPV AIAVAIIVSL PWALAVHGQE PDYWRFFFWH 

       250        260        270        280        290        300 
EHIRRFAGDD AQHDAPWWFY LPLLVAFSLP WVGMLPVAFK QAWQTRRETG IAFLGLWLLM 

       310        320        330        340        350        360 
PLLFFSLSNG KLPTYILPCL LPLALLLGHA LADRLRLEQG RALGLNGLLN LLLGLVTLIG 

       370        380        390        400        410        420 
LVYVQLKRPL YDHELHSLVL VFIALTGWII SNLLQAFRPL QCWAAPAVGS LLLIALLPAA 

       430        440        450        460        470        480 
LPRSVVANKM PDQFVLAHQK ELTATTHLLS NDLGAASALS WRVKRPQVAL YNTIGELKYG 

       490        500        510        520        530        540 
LAYPDGIQQR VDPDQVQQWM REARKTGSVG VVMRVKGQDE LDELDRLPKD GVRYEQGNLV 


IMILPQEAS

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000094 Genomic DNA. Translation: ABA74586.1.
RefSeqYP_348576.1. NC_007492.2.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING205922.Pfl01_2845.

Protein family/group databases

CAZyGT83. Glycosyltransferase Family 83.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA74586; ABA74586; Pfl01_2845.
GeneID3712609.
KEGGpfo:Pfl01_2845.
PATRIC19887851. VBIPseFlu44242_2878.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1807.
HOGENOMHOG000273002.
KOK07264.
OMAVACLPWS.
ProtClustDBPRK13279.

Enzyme and pathway databases

BioCycPFLU205922:GJBD-2891-MONOMER.
UniPathwayUPA00037.

Family and domain databases

HAMAPMF_01165. ArnT_transfer.
InterProIPR022839. ArnT_tfrase.
IPR003342. Glyco_trans_39.
[Graphical view]
PfamPF02366. PMT. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameARNT2_PSEPF
AccessionPrimary (citable) accession number: Q3KCB9
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: November 8, 2005
Last modified: May 1, 2013
This is version 61 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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