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Q3K9J0 (UPPP2_PSEPF) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 68. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Undecaprenyl-diphosphatase 2

EC=3.6.1.27
Alternative name(s):
Bacitracin resistance protein 2
Undecaprenyl pyrophosphate phosphatase 2
Gene names
Name:uppP2
Ordered Locus Names:Pfl01_3826
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP-Rule MF_01006

Catalytic activity

Ditrans,octacis-undecaprenyl diphosphate + H2O = ditrans,octacis-undecaprenyl phosphate + phosphate. HAMAP-Rule MF_01006

Subcellular location

Cell inner membrane; Multi-pass membrane protein By similarity HAMAP-Rule MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.

Sequence similarities

Belongs to the UppP family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 277277Undecaprenyl-diphosphatase 2 HAMAP-Rule MF_01006
PRO_0000227631

Regions

Transmembrane43 – 6321Helical; Potential
Transmembrane87 – 10721Helical; Potential
Transmembrane109 – 12921Helical; Potential
Transmembrane183 – 20321Helical; Potential
Transmembrane214 – 23421Helical; Potential
Transmembrane254 – 27421Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q3K9J0 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 3454560A3AACE8EF

FASTA27730,394
        10         20         30         40         50         60 
MDLLTLFKVL ILGAVEGLTE FLPISSTGHQ IIVADLLEFG GERAMAFNII IQLGAILAVV 

        70         80         90        100        110        120 
WEFRPKIFEI VKGLPTQSNA QRFTRNLLIA FFPAVILGVL FADTIHEYLF NPITVAVALV 

       130        140        150        160        170        180 
VGGIVMLWAE QRDHVVSVDH VDDMKWADAL KIGCVQCLAM IPGTSRSGST IIGGLLFGLS 

       190        200        210        220        230        240 
RKAATEFSFF LAMPTMVGAA VYSGYKYREL FQSSDLPVFA LGFVVAFIFA MIAVRGLLKF 

       250        260        270 
IANHSYATFA WYRIAFGLLI LATWQFGWVN WTAAAAA 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CP000094 Genomic DNA. Translation: ABA75564.1.
RefSeqYP_349555.1. NC_007492.2.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING205922.Pfl01_3826.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaABA75564; ABA75564; Pfl01_3826.
GeneID3714854.
KEGGpfo:Pfl01_3826.
PATRIC19889751. VBIPseFlu44242_3820.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1968.
HOGENOMHOG000218356.
KOK06153.
OMALMIYMEN.
OrthoDBEOG6QP13M.
ProtClustDBPRK12554.

Enzyme and pathway databases

BioCycPFLU205922:GJBD-3876-MONOMER.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
InterProIPR003824. UppP.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
TIGRFAMsTIGR00753. undec_PP_bacA. 1 hit.
ProtoNetSearch...

Entry information

Entry nameUPPP2_PSEPF
AccessionPrimary (citable) accession number: Q3K9J0
Entry history
Integrated into UniProtKB/Swiss-Prot: March 21, 2006
Last sequence update: November 8, 2005
Last modified: February 19, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families