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Protein

Peptide methionine sulfoxide reductase MsrB

Gene

msrB

Organism
Pseudomonas fluorescens (strain Pf0-1)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Peptide-L-methionine + thioredoxin disulfide + H2O = peptide-L-methionine (R)-S-oxide + thioredoxin.UniRule annotation

Cofactori

Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit. The zinc ion is important for the structural integrity of the protein.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi47ZincPROSITE-ProRule annotation1
Metal bindingi50ZincPROSITE-ProRule annotation1
Metal bindingi96ZincPROSITE-ProRule annotation1
Metal bindingi99ZincPROSITE-ProRule annotation1
Active sitei119NucleophilePROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Peptide methionine sulfoxide reductase MsrBUniRule annotation (EC:1.8.4.12UniRule annotation)
Alternative name(s):
Peptide-methionine (R)-S-oxide reductaseUniRule annotation
Gene namesi
Name:msrBUniRule annotation
Ordered Locus Names:Pfl01_3982
OrganismiPseudomonas fluorescens (strain Pf0-1)
Taxonomic identifieri205922 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002704 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000682881 – 131Peptide methionine sulfoxide reductase MsrBAdd BLAST131

Interactioni

Protein-protein interaction databases

STRINGi205922.Pfl01_3982.

Structurei

3D structure databases

ProteinModelPortaliQ3K935.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini8 – 130MsrBPROSITE-ProRule annotationAdd BLAST123

Sequence similaritiesi

Belongs to the MsrB Met sulfoxide reductase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105E0X. Bacteria.
COG0229. LUCA.
HOGENOMiHOG000243424.
KOiK07305.
OMAiYKASHKF.
OrthoDBiPOG091H064P.

Family and domain databases

HAMAPiMF_01400. MsrB. 1 hit.
InterProiView protein in InterPro
IPR028427. Met_Sox_Rdtase.
IPR002579. Met_Sox_Rdtase_MsrB.
IPR011057. Mss4-like.
PANTHERiPTHR10173. PTHR10173. 1 hit.
PfamiView protein in Pfam
PF01641. SelR. 1 hit.
SUPFAMiSSF51316. SSF51316. 1 hit.
TIGRFAMsiTIGR00357. TIGR00357. 1 hit.
PROSITEiView protein in PROSITE
PS51790. MSRB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q3K935-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEKIEKTLEE WRAMLDPEQF NVCRLSATER PFSGKYNATK TDGVYHCICC
60 70 80 90 100
NEPLFDSKTK FDSGCGWPSF YAPIGDNAMT EIRDTSHGMI RTEVKCAKCD
110 120 130
AHLGHVFPDG PPPTGLRYCI NSVCLDLVPR E
Length:131
Mass (Da):14,753
Last modified:November 8, 2005 - v1
Checksum:i211A36D8A5C64B38
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000094 Genomic DNA. Translation: ABA75719.1.
RefSeqiWP_011335291.1. NC_007492.2.

Genome annotation databases

EnsemblBacteriaiABA75719; ABA75719; Pfl01_3982.
KEGGipfo:Pfl01_3982.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiMSRB_PSEPF
AccessioniPrimary (citable) accession number: Q3K935
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 5, 2008
Last sequence update: November 8, 2005
Last modified: June 7, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families