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Q3K889 (Q3K889_PSEPF) Unreviewed, UniProtKB/TrEMBL

Last modified December 14, 2011. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
6,7-dimethyl-8-ribityllumazine synthase 1 HAMAP MF_00178
Short name=DMRL synthase 1 HAMAP MF_00178
Short name=Lumazine synthase 1 HAMAP MF_00178
EC=2.5.1.9 HAMAP MF_00178
Alternative name(s):
Riboflavin synthase beta chain 1 HAMAP MF_00178
Gene names
Name:ribH EMBL ABA76015.1
Synonyms:ribH1 HAMAP MF_00178
Ordered Locus Names:Pfl01_4278
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP] EMBL ABA76015.1
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length169 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2-butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes the condensation of 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate yielding 6,7-dimethyl-8-lumazine By similarity. HAMAP MF_00178

Catalytic activity

2 6,7-dimethyl-8-(1-D-ribityl)lumazine = riboflavin + 4-(1-D-ribitylamino)-5-amino-2,6-dihydroxypyrimidine. HAMAP MF_00178

Pathway

Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 2/2. HAMAP MF_00178

Sequence similarities

Belongs to the DMRL synthase family. HAMAP MF_00178

Ontologies

Keywords
   Biological processRiboflavin biosynthesis HAMAP MF_00178
   Molecular functionTransferase HAMAP MF_00178 EMBL ABA76015.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processriboflavin biosynthetic process

Inferred from electronic annotation. Source: HAMAP

   Cellular componentriboflavin synthase complex

Inferred from electronic annotation. Source: InterPro

   Molecular functionriboflavin synthase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q3K889 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: B859B2B42E9F64FE

FASTA16918,845
        10         20         30         40         50         60 
MQPTAIDSKS KHTHGERVAF IQACWHKEIV DQSRKGFLAE MIAQGYQESD IDFFEVGGAF 

        70         80         90        100        110        120 
EMPLHAKLLA KTGRYAGIVA AALVVDGGIY RHEFVAQSVV SGLMQVQLET EVPVFSVSLT 

       130        140        150        160 
PHHFHAGEEH QKFFFEHFVH KGQEAAKTCA DTLQKVRALR RTEPRAVAV

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000094 Genomic DNA. Translation: ABA76015.1.
RefSeqYP_350006.1. NC_007492.2.

3D structure databases

ProteinModelPortalQ3K889.
SMRQ3K889. Positions 17-146.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3K889.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3712890.
GenomeReviewsGene locus Pfl01_4278 in contig CP000094_GR.
KEGGpfo:Pfl01_4278.
PATRIC19890700. VBIPseFlu44242_4278.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0054.
HOGENOMHBG311126.
OMARRYTAIV.
PhylomeDBQ3K889.
ProtClustDBPRK12419.

Enzyme and pathway databases

BioCycPFLU205922:PFL_4278-MONOMER.

Family and domain databases

HAMAPMF_00178. Lumazine_synth.
[Tree]
InterProIPR002180. DMRL_synthase.
[Graphical view]
Gene3DG3DSA:3.40.50.960. DMRL_synthase. 1 hit.
KOK00794.
PANTHERPTHR21058. DMRL_synthase. 1 hit.
PfamPF00885. DMRL_synthase. 1 hit.
[Graphical view]
SUPFAMSSF52121. DMRL_synthase. 1 hit.
ProtoNetSearch...

Entry information

Entry nameQ3K889_PSEPF
AccessionPrimary (citable) accession number: Q3K889
Entry history
Integrated into UniProtKB/TrEMBL: November 8, 2005
Last sequence update: November 8, 2005
Last modified: December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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