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Reviewed, UniProtKB/Swiss-Prot Q3K886 (ASTB_PSEPF)

Last modified June 16, 2009. Version 33. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    N-succinylarginine dihydrolase
    EC=3.5.3.23
Gene names
Name: astB
Ordered Locus Names: Pfl01_4281
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

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Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity.

Catalytic activity

N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the succinylarginine dihydrolase family.

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Ontologies

Keywords
   Biological processArginine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine catabolic process to glutamate

Inferred from electronic annotation. Source: HAMAP

   Molecular functionN-succinylarginine dihydrolase activity

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448N-succinylarginine dihydrolase HAMAP MF_01172
PRO_0000262366

Regions

Region19 – 2810Substrate binding By similarity
Region137 – 1382Substrate binding By similarity

Sites

Active site1741 By similarity
Active site2501 By similarity
Active site3711Nucleophile By similarity
Binding site1101Substrate By similarity
Binding site2141Substrate By similarity
Binding site2521Substrate By similarity
Binding site3651Substrate By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q3K886-1 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 66F70560E487848A

FASTA44848,728
        10         20         30         40         50         60 
MKSYEVNFDG LVGPTHNYGG LSYGNVASQS NSQQSSNPKE AALQGLAKMK ALMEMGFQQG 

        70         80         90        100        110        120 
VLAPQERPDV AALRRLGFSG TDAQVIERAA KEAMPLLVAS CSASSMWVAN AATVSPSADT 

       130        140        150        160        170        180 
ADGRVHFTAA NLNCKYHRSI EHPTTSRVLG AMFANQQHFA HHAALPAVAQ FGDEGAANHT 

       190        200        210        220        230        240 
RFCREYGDAG VEFFVFGRSA FDTRYPAPQK YPARQTLEAS QAVARLHGLR DDGVVYAQQN 

       250        260        270        280        290        300 
PAVIDQGVFH NDVIAVGNGE VLFYHEDAFL DTDQMLAELQ AKLAKVGGKF QSVCVPRSAV 

       310        320        330        340        350        360 
TVDDAVRSYL FNSQLLSRPD GSMLLIVPEE CRGNERVWNY LQGLTSSGGL IREVKVFDLK 

       370        380        390        400        410        420 
QSMQNGGGPA CLRLRVALNE TELAAVNPGV IMTAPLYGSL TAWVEKHYRD RLTESDLADP 

       430        440 
QLLLECRTAL DELTQILKLG AVYPFQIN

« Hide

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References

[1]"Complete sequence of Pseudomonas fluorescens PfO-1."
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J., Larimer F., Land M., Kyripides N., Anderson I., Richardson P.
Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

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Cross-references

Sequence databases

CP000094 Genomic DNA. Translation: ABA76018.1.
RefSeqYP_350009.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID3712893.
GenomeReviewsGene locus Pfl01_4281 in contig CP000094_GR.
KEGGpfo:Pfl01_4281.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ3K886.
OMAQ3K886. KMKALME.

Enzyme and pathway databases

BioCycPFLU205922:PFL_4281-MON.

Family and domain databases

HAMAPMF_01172.
[Tree]
InterProIPR007079. SuccinylArg_d-Hdrlase_AstB.
[Graphical view]
Gene3DG3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit.
PfamPF04996. AstB. 1 hit.
[Graphical view]
TIGRFAMsTIGR03241. arg_catab_astB. 1 hit.
ProtoNetSearch...

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Entry information

Entry nameASTB_PSEPF
AccessionPrimary (citable) accession number: Q3K886
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 8, 2005
Last modified: June 16, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents