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Q3K886 (ASTB_PSEPF) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
N-succinylarginine dihydrolase
EC=3.5.3.23
Gene names
Name:astB
Ordered Locus Names:Pfl01_4281
OrganismPseudomonas fluorescens (strain Pf0-1) [Complete proteome] [HAMAP]
Taxonomic identifier205922 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Pseudomonadales › Pseudomonadaceae › Pseudomonas

Protein attributes

Sequence length448 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the hydrolysis of N(2)-succinylarginine into N(2)-succinylornithine, ammonia and CO2 By similarity. HAMAP MF_01172

Catalytic activity

N(2)-succinyl-L-arginine + 2 H2O = N(2)-succinyl-L-ornithine + 2 NH3 + CO2. HAMAP MF_01172

Pathway

Amino-acid degradation; L-arginine degradation via AST pathway; L-glutamate and succinate from L-arginine: step 2/5. HAMAP MF_01172

Subunit structure

Homodimer By similarity. HAMAP MF_01172

Sequence similarities

Belongs to the succinylarginine dihydrolase family.

Ontologies

Keywords
   Biological processArginine metabolism
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processarginine metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionN-succinylarginine dihydrolase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 448448N-succinylarginine dihydrolase HAMAP MF_01172
PRO_0000262366

Regions

Region19 – 2810Substrate binding By similarity
Region137 – 1382Substrate binding By similarity

Sites

Active site1741 By similarity
Active site2501 By similarity
Active site3711Nucleophile By similarity
Binding site1101Substrate By similarity
Binding site2141Substrate By similarity
Binding site2521Substrate By similarity
Binding site3651Substrate By similarity

Sequences

Sequence LengthMass (Da)Tools
Q3K886 [UniParc].

Last modified November 8, 2005. Version 1.
Checksum: 66F70560E487848A

FASTA44848,728
        10         20         30         40         50         60 
MKSYEVNFDG LVGPTHNYGG LSYGNVASQS NSQQSSNPKE AALQGLAKMK ALMEMGFQQG 

        70         80         90        100        110        120 
VLAPQERPDV AALRRLGFSG TDAQVIERAA KEAMPLLVAS CSASSMWVAN AATVSPSADT 

       130        140        150        160        170        180 
ADGRVHFTAA NLNCKYHRSI EHPTTSRVLG AMFANQQHFA HHAALPAVAQ FGDEGAANHT 

       190        200        210        220        230        240 
RFCREYGDAG VEFFVFGRSA FDTRYPAPQK YPARQTLEAS QAVARLHGLR DDGVVYAQQN 

       250        260        270        280        290        300 
PAVIDQGVFH NDVIAVGNGE VLFYHEDAFL DTDQMLAELQ AKLAKVGGKF QSVCVPRSAV 

       310        320        330        340        350        360 
TVDDAVRSYL FNSQLLSRPD GSMLLIVPEE CRGNERVWNY LQGLTSSGGL IREVKVFDLK 

       370        380        390        400        410        420 
QSMQNGGGPA CLRLRVALNE TELAAVNPGV IMTAPLYGSL TAWVEKHYRD RLTESDLADP 

       430        440 
QLLLECRTAL DELTQILKLG AVYPFQIN

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000094 Genomic DNA. Translation: ABA76018.1.
RefSeqYP_350009.1. NC_007492.2.

3D structure databases

HSSPHSSP built from PDB template 1YNF based on UniProtKB P76216.
ProteinModelPortalQ3K886.
SMRQ3K886. Positions 3-447.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ3K886.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3712893.
GenomeReviewsGene locus Pfl01_4281 in contig CP000094_GR.
KEGGpfo:Pfl01_4281.
PATRIC19890706. VBIPseFlu44242_4281.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG3724.
HOGENOMHBG289862.
OMAVIAVGNK.
ProtClustDBPRK13281.

Enzyme and pathway databases

BioCycPFLU205922:PFL_4281-MONOMER.

Family and domain databases

HAMAPMF_01172. AstB.
[Tree]
InterProIPR007079. SuccinylArg_d-Hdrlase_AstB.
[Graphical view]
Gene3DG3DSA:3.75.10.20. SuccinylArg_di_hydro. 1 hit.
KOK01484.
PfamPF04996. AstB. 1 hit.
[Graphical view]
TIGRFAMsTIGR03241. Arg_catab_astB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameASTB_PSEPF
AccessionPrimary (citable) accession number: Q3K886
Entry history
Integrated into UniProtKB/Swiss-Prot: November 28, 2006
Last sequence update: November 8, 2005
Last modified: January 25, 2012
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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