ID   GPH_PSEPF               Reviewed;         272 AA.
AC   Q3K5U8;
DT   30-MAY-2006, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   16-JUN-2009, entry version 30.
DE   RecName: Full=Phosphoglycolate phosphatase;
DE            Short=PGPase;
DE            Short=PGP;
DE            EC=3.1.3.18;
GN   OrderedLocusNames=Pfl01_5119;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyripides N., Anderson I., Richardson P.;
RT   "Complete sequence of Pseudomonas fluorescens PfO-1.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Specifically catalyzes the dephosphorylation of 2-
CC       phosphoglycolate. Is involved in the dissimilation of the
CC       intracellular 2-phosphoglycolate formed during the DNA repair of
CC       3'-phosphoglycolate ends, a major class of DNA lesions induced by
CC       oxidative stress (By similarity).
CC   -!- CATALYTIC ACTIVITY: 2-phosphoglycolate + H(2)O = glycolate +
CC       phosphate.
CC   -!- PATHWAY: Organic acid metabolism; glycolic acid biosynthesis;
CC       glycolic acid from 2-phosphoglycolic acid: step 1/1.
CC   -!- SIMILARITY: Belongs to the HAD-like hydrolase superfamily.
CC       CbbY/cbbZ/gph/yieH family.
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DR   EMBL; CP000094; ABA76856.1; -; Genomic_DNA.
DR   RefSeq; YP_350847.1; -.
DR   GeneID; 3717037; -.
DR   GenomeReviews; CP000094_GR; Pfl01_5119.
DR   KEGG; pfo:Pfl01_5119; -.
DR   HOGENOM; Q3K5U8; -.
DR   OMA; Q3K5U8; DSSNDAQ.
DR   BioCyc; PFLU205922:PFL_5119-MON; -.
DR   GO; GO:0008967; F:phosphoglycolate phosphatase activity; IEA:HAMAP.
DR   GO; GO:0005975; P:carbohydrate metabolic process; IEA:HAMAP.
DR   HAMAP; MF_00495; -; 1.
DR   InterPro; IPR005834; Dehalogen-like_hydro.
DR   InterPro; IPR006439; HAD-SF_hydro_IA_v1.
DR   InterPro; IPR006402; HAD-SF_hydro_IA_v3.
DR   InterPro; IPR005833; Haloacid_DH/epoxide_hydro.
DR   InterPro; IPR006346; PGP_bact.
DR   Pfam; PF00702; Hydrolase; 1.
DR   PRINTS; PR00413; HADHALOGNASE.
DR   TIGRFAMs; TIGR01549; HAD-SF-IA-v1; 1.
DR   TIGRFAMs; TIGR01509; HAD-SF-IA-v3; 1.
DR   TIGRFAMs; TIGR01449; PGP_bact; 1.
PE   3: Inferred from homology;
KW   Carbohydrate metabolism; Complete proteome; Hydrolase.
FT   CHAIN         1    272       Phosphoglycolate phosphatase.
FT                                /FTId=PRO_0000238167.
FT   ACT_SITE     19     19       Nucleophile (By similarity).
SQ   SEQUENCE   272 AA;  29558 MW;  0E4BC755EE6F830D CRC64;
     MSGFEQLFPG QLPRLVMFDL DGTLIDSVPD LAAAVDNMLL SLGRKPAGIE SVREWVGNGA
     PVLVRRALAG GIDHSSVDDV EAEHALEVFM EAYGASHELT VVYPGVRDTL KWLHKQGVAM
     ALITNKPERF VAPLLDQMKI GRYFKWIIGG DTLPQKKPDP AALFFVMKMS GIPASQSLFV
     GDSRSDVLAA KAAGVKCVGL SYGYNHGRPI AEESPTLVID DLRKLIPGCL DTAAEITLPD
     AAQSPSGNAI VVVTRKLWMK VIKALARWRW RA
//