ID   APAH_PSEPF              Reviewed;         293 AA.
AC   Q3K5T0;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-NOV-2005, sequence version 1.
DT   16-JUN-2009, entry version 28.
DE   RecName: Full=Bis(5'-nucleosyl)-tetraphosphatase, symmetrical;
DE            EC=3.6.1.41;
DE   AltName: Full=Diadenosine tetraphosphatase;
DE   AltName: Full=Ap4A hydrolase;
DE   AltName: Full=Diadenosine 5',5'''-P1,P4-tetraphosphate pyrophosphohydrolase;
GN   Name=apaH; OrderedLocusNames=Pfl01_5137;
OS   Pseudomonas fluorescens (strain Pf0-1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=205922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Saunders E.H., Schmutz J.,
RA   Larimer F., Land M., Kyripides N., Anderson I., Richardson P.;
RT   "Complete sequence of Pseudomonas fluorescens PfO-1.";
RL   Submitted (AUG-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to
CC       yield ADP (By similarity).
CC   -!- CATALYTIC ACTIVITY: P(1),P(4)-bis(5'-adenosyl) tetraphosphate +
CC       H(2)O = 2 ADP.
CC   -!- SIMILARITY: Belongs to the Ap4A hydrolase family.
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DR   EMBL; CP000094; ABA76874.1; -; Genomic_DNA.
DR   RefSeq; YP_350865.1; -.
DR   GeneID; 3717268; -.
DR   GenomeReviews; CP000094_GR; Pfl01_5137.
DR   KEGG; pfo:Pfl01_5137; -.
DR   HOGENOM; Q3K5T0; -.
DR   OMA; Q3K5T0; LVFGHWA.
DR   BioCyc; PFLU205922:PFL_5137-MON; -.
DR   GO; GO:0008803; F:bis(5'-nucleosyl)-tetraphosphatase (symmetr...; IEA:HAMAP.
DR   HAMAP; MF_00199; -; 1.
DR   InterPro; IPR004617; ApaH.
DR   InterPro; IPR004843; M-pesterase.
DR   Pfam; PF00149; Metallophos; 1.
DR   PIRSF; PIRSF000903; B5n-ttraPtase_sm; 1.
DR   TIGRFAMs; TIGR00668; apaH; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Hydrolase.
FT   CHAIN         1    293       Bis(5'-nucleosyl)-tetraphosphatase,
FT                                symmetrical.
FT                                /FTId=PRO_1000012081.
SQ   SEQUENCE   293 AA;  32882 MW;  BE4D21F49B5D116A CRC64;
     MATYAVGDLQ GCLEPLKCLL QQVAFDPALD RLWLVGDLVN RGPQSLETLR FLYGMRESLV
     CVLGNHDLHL LAAAKNIERL KKSDTLREIL EAPDCAELME WLRQQKLMHY DEQREVAMVH
     AGIPPQWSLR KALKYAEEVE TALRDDNLLP PFLDGMYGNE PAKWDSDLKG VTRLRVITNY
     FTRMRFCTAE GKLDLKSKEG LDTAPPGYKP WFQHKERKTR GLRIIFGHWA ALEGNVHEPG
     ICALDTGCVW GGSLTLMNVD SGERLSCKCD EHGAALPTVA PLITESSPVS APR
//